Basolateral Cl- transport is stimulated by terbutaline in adult rat alveolar epithelial cells

Journal of Membrane Biology

Volumn 191, Issue 2, 2003, Pages 133-139

  Lee, S Y ^c   Maniak, P J ^a   Rhodes, R ^b   Ingbar, D H ^b   O'Grady, S M ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c NONE

Author keywords

Alveolar fluid clearance; CFTR; Cl channels; Cystic fibrosis; KCC; KCl cotransport

Indexed keywords

CARRIER PROTEIN; CHLORIDE ION; MESSENGER RNA; POTASSIUM CHLORIDE; TERBUTALINE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; BASOLATERAL MEMBRANE; CHLORIDE TRANSPORT; LUNG ALVEOLUS EPITHELIUM; MEMBRANE POTENTIAL; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM TRANSPORT; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CELL MEMBRANE; CELLS, CULTURED; CHLORINE; ION TRANSPORT; MALE; PROTEIN ISOFORMS; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY MUCOSA; SYMPORTERS; TERBUTALINE;

ANIMALIA;

EID: 0013155593     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-002-1049-x     Document Type: Article

References (26)

1. Borok, Z., Hami, A., Danto, S.I., Lubman, R.L., Kim, K.J., Crandall E.D. 1996. Effects of EGF on alveolar epithelial junctional permeability and active sodium transport. Am. J. Physiol. 270:L559-L565
2. Cheek, J.M., Kim, K.J., Crandall, E.D. 1989. Tight monolayers of rat alveolar epithelial cells: bioelectric properties and active sodium transport. Am. J. Physiol. 251:C688-C693
3. Crandall, E.D., Heming, T.A., Palombo, R.L., Goodman, B.E. 1986. Effects of terbutaline on sodium transport in isolated perfused rat lung. J. Appl. Physiol. 66:289-294
4. Fang, X., Fukuda, N., Barbry, P., Sartori, C., Verkman, A.S. Matthay, M.A. 2002. Novel role for CFTR in fluid absorption from the distal airspaces of the lung. J. Gen. Physiol. 119:199-207
5. Fiedler, M.A., Nemecz, Z.K., Shull, G.E. 1992. Cloning and sequence analysis of rat cystic fibrosis transmembrane conductance regulator. Am. J. Physiol. 262:L779-784
6. Gillen, C.M., Brill, S., Payne, J.A., Forbush, B. 1996. Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family. J. Biol. Chem. 271:16237-16244
7. Jiang, X., Ingbar, D.H., O'Grady, S.M. 1998. Adrenergic stimulation of Na transport across alveolar epithelial cells involves activation of apical Cl channels. Am. J. Physiol. 275:C1610-1620
8. Jiang, X., Ingbar, D.H., O'Grady, S.M. 2001. Adrenergic regulation of ion transport across adult alveolar epithelial cells: Effects on Cl channel activation and transport function in cultures with an apical air interface. J. Membrane Biol. 181:195-204
9. - fluxes to net ion transport by alveolar epithelium. Respir. Physiol. 85:245-256
10. Lauf, P.K., Adragna, N.C. 2000. K-Cl cotransport: properties and molecular mechanism. Cell Physiol. Biochem. 10:341-354
11. + transport in ATII cells by cAMP: we agree to disagree and do more experiments. Am. J. Physiol. 278:L233-L238
12. Matalon, S., O'Brodovich, H. 1999. Sodium channels in alveolar epithelial cells: molecular characterization, biophysical properties, and physiological significance. Annu. Rev. Physiol. 61:627-661
13. McCray, P.B., Bettencourt, J.D., Bastacky, J., Denning, G.M., Welsh, M.J. 1993. Expression of CFTR and a cAMP-stimulated chloride secretory current in cultured human fetal alveolar epithelial cells. Am. J. Respir. Cell. Mol. Biol. 9:578-585
14. - cotransporters KCC1 and KCC4. J. Biol. Chem. 275:30326-30334
15. Mount, D.B., Mercado, A., Song, L., Xu J., George, A.L. Jr., Delpire, E., Gamba, G. 1999. Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family. J. Biol. Chem. 274:16355-16362
16. O'Brodovich, H., Rafii, B., Post, M. 1990. Bioelectric properties of fetal alveolar epithelial monolayers. Am. J. Physiol. 258:L201-206
17. O'Brodovich, H. 1996. Epithelial ion transport in fetal and perinatal lung. Am. J. Physiol. 261:C555-564
18. + transport in adult alveolar epithelial cells. Am. J. Physiol. 278:L239-L244
19. Payne, J.A., Stevenson, T.J., Donaldson, L.F. 1996. Molecular characterization of a putative K-Cl cotransporter in rat brain. A neuronal-specific isoform. J. Biol. Chem. 271:16245-16252
20. Race, J.E., Makhlouf, F.N., Logue, P.J., Wilson, F.H., Dunham, P.B., Holtzman, E.J. 1999. Molecular cloning and functional characterization of KCC3, a new K-Cl cotransporter. Am. J. Physiol. 277:C1210-1219
21. Reuss, L. 1983. Basolateral KCl co-transport in a NaCl-absorbing epithelium. Nature 305:723-726
22. Saldias, F., Lecuona, E., Friedman, E., Barnard, M.L., Ridge, K.M., Sznajder, J.I. 1998. Modulation of lung liquid clearance by isoproterenol in rat lungs. Am. J. Physiol. 274:L694-L701
23. Sangan, P., Brill, S.R., Sangan, S., Forbush, B., Binder, H.J. 2000. Basolateral K-Cl cotransporter regulates colonic potassium absorption in potassium depletion. J. Biol. Chem. 275:30813-30816
24. Saumon, G., Basset, G., Bouchonnet, F., Crone, C., 1987. cAMP and β-adrenergic stimulation of rat alveolar epithelium: Effects on fluid absorption and paracellular permeability. Pfluegers Arch. 410:464-470
25. Warnock, D.G., Eveloff, J., 1989. K-Cl cotransport systems. Kidney Int. 412-417
26. Widdcombe, J.H. 2000. How does cAMP increase active Na absorption across alveolar epithelium? Am. J. Physiol. 278:L231-L232