The potential of proton and light ion beams in radiotherapy

Acta Oncologica

Volumn 42, Issue 2, 2003, Pages 107-114

  Turesson, Ingela ^a   Johansson, Karl Axel ^b   Mattsson, Sören ^c  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ION BEAMS; ONCOLOGY; PROTONS;

LIGHT ION BEAMS;

RADIOTHERAPY;

ION;

CANCER RADIOTHERAPY; CANCER RESEARCH; LIGHT; MEDICAL SOCIETY; PRIORITY JOURNAL; PROTON RADIATION; RADIATION DOSE; REVIEW; SWEDEN;

HUMANS; IONS; NEOPLASMS; PROTONS; RADIATION ONCOLOGY; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; SWEDEN;

EID: 0012709616     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/12841860310004968     Document Type: Review

References (49)

1. Intensity Modulated Radiation Therapy Collaborative Working Group. Intensity-modulated radiotherapy: current status and issues of interest. Int J Radiat Oncol Biol Phys 2001; 51: 880-914.
2. Tubiana M, Eschwege F. Conformal radiotherapy and intensity-modulated radiotherapy - clinical data. Acta Oncol 2000; 39: 555-67.
3. Bonnett DE. Current developments in proton therapy: a review. Phys Med Biol 1993; 38: 1371-92.
4. Levy RP, Schulte RW, Slater JD, et al. Stereotactic radiosurgery - the role of charged particles. Acta Oncol 1999; 38: 165-9.
5. Fuss M, Loredo LN, Blacharski PA, et al. Proton radiation therapy for medium and large choroidal melanoma: preservation of the eye and its functionality. Int J Radiat Oncol Biol Phys 2001; 49: 1053-9.
6. Munzenrider JE, Liebsch N. Proton therapy for tumors of the skull base. Strahlenther Onkol 1999; 175(Suppl): 257-63.
7. The Proton Therapy Working Party. Proton therapy for base of skull chordoma: a report for the Royal College of Radiologists. Clin Oncol 2000; 12: 75-9.
8. Shipley WU, Verhey LJ, Munzenrider JE, et al. Advanced prostate cancer: the results of a randomized comparative trial of high dose irradiation boosting with conformal protons compared with conventional dose irradiation using photons alone. Int J Radiat Oncol Biol Phys 1995; 32: 3-12.
9. Isacsson U, Lennernäs B, Grusell E, et al. Comparative treatment planning between proton and X-ray therapy in esophageal cancer. Int J Radiat Oncol Biol Phys 1998; 41: 441-50.
10. Isacsson U, Hagberg H, Johansson KA, et al. Potential advantages of protons over conventional radiation beams for paraspinal tumours. Radiother Oncol 1997; 45: 63-70.
11. Isacsson U, Montelius A, Jung B, et al. Comparative treatment planning between proton and x-ray therapy in locally advanced rectal cancer. Radiother Oncol 1996; 41: 263-72.
12. Baumert BG, Lomax AJ, Miltchev V, et al. A comparison of dose distributions of proton and photon beams in stereotactic conformal radiotherapy of brain lesions. Int J Radiat Oncol Biol Phys 2001; 49: 1439-49.
13. Cella L, Lomax A, Miralbell R. Potential role of intensity modulated proton beams in prostate cancer radiotherapy. Int J Radiat Oncol Biol Phys 2001; 49: 217-23.
14. Fuss M, Hug EB, Schaefer RA, et al. Proton radiation therapy (PRT) for pediatric optic pathway gliomas: comparison with 3D planned conventional photons and a standard photon technique. Int J Radiat Oncol Biol Phys 1999; 45: 1117-26.
15. Miralbell R, Crowell C, Suit H. Potential improvement of three dimensional treatment planning and proton therapy in the outcome of maxillary sinus cancer. Int J Radiat Oncol Biol Phys 1997; 22: 305-10.
16. Miralbell R, Lomax A, Bortfeld T, et al. Potential role of proton therapy in the treatment of pediatric medulloblastoma/primitive neuroectodermal tumors: reduction of the supratentorial target volume. Int J Radiat Oncol Biol Phys 1997; 38: 477-84.
17. Miralbell R, Lomax A, Russo M. Potential role of proton therapy in the treatment of pediatric medulloblastoma/primitive neuro-ectodermal tumors: spinal theca irradiation. Int J Radiat Oncol Biol Phys 1997; 38: 805-11.
18. Oelfke U, Bortfeld T. Intensity modulated radiotherapy with charged particle beams: studies of inverse treatment planning for rotation therapy. Med Phys 2000; 27: 1246-57.
19. Zurlo A, Lomax A, Hoess A, et al. The role of proton therapy in the treatment of large irradiation volumes: a comparative planning study of pancreatic and biliary tumors. Int J Radiat Oncol Biol Phys 2000; 48: 277-88.
20. Cozzi L, Fogliata A, Lomax A, et al. A treatment planning comparison of 3D conformal therapy, intensity modulated photon therapy and proton therapy for treatment of advanced head and neck tumours. Radiother Oncol 2001; 61: 287-927.
21. Lee C, Tait D, Nahum A, et al. Comparison of proton therapy and conformal X-ray therapy in non-small cell lung cancer (NSCLC). Br J Radiat 1999; 72: 1078-84.
22. Lin R, Hug EB, Schaefer RA, et al. Conformal proton radiation therapy of the posterior fossa: a study comparing protons with three-dimensional planned photons in limiting dose to auditory structures. Int J Radiat Oncol Biol Phys 2000; 48: 1219-26.
23. Johansson J, Isacsson U, Lindman H, et al. Node-positive left-sided breast cancer patients after breast-conserving surgery: potential outcomes of radiotherapy modalities and techniques. Radiother Oncol 2002; 65: 89-98.
24. Fogliata A, Bolsi A, Cozzi L. Critical appraisal of treatment techniques based on conventional photon beams, intensity modulated photon beams and proton beams for therapy of intact breast. Radiother Oncol 2002; 62: 137-45.
25. Paganetti H, Niemierko A, Ancukiewicz M, et al. Relative biological effectiveness (RBE) values for proton beam therapy. Int J Radiat Oncol Biol Phys 2002; 53: 407-21.
26. Tilly N. Radiobiological investigations of proton and light ion therapy. Stockholm. Thesis: Stockholm University; 2002.
27. Brahme A. Development of radiation therapy optimization. Acta Oncol 2000; 39: 579-95.
28. Brahme A, Nilsson J, Belkic D. Biologically optimized radiation therapy. Acta Oncol 2001; 40: 725-34.
29. Tilikidis A, Brahme A. Microdosimetric description of beam quality and biological effectiveness in radiation therapy. Acta Oncol 1994; 33: 457-69.
30. Stenerlöw B, Pettersson OA, Essand M, et al. Irregular variations in radiation sensitivity when the linear energy transfer is increased. Radiother Oncol 1995; 36: 133-42.
31. Peters LJ. Targeting hypoxia in head and neck cancer. Acta Oncol 2001; 40: 937-40.
32. Zackrisson B, Kjellén E, Glimelius B, et al. and the Swedish Cancer Society Investigation Group. Sensitizing and protective substances in radiotherapy and predictive assays. Acta Oncol 2002; 41: 615-22.
33. Steel GG. Basic clinical radiology. 3rd ed. London: Edward Arnold; 2002.
34. Kraft G. Tumor therapy with ion beams. Nucl Instr Meth Phys Res A 2000; 454: 1-10.
35. Brahme A, Lewensohn R, Ringborg U, et al. Design of a centre for biologically optimised light ion therapy in Stockholm. Nucl Inst Meth B 2001; 184: 569-88.
36. Koike S, Ando K, Uzawa A, et al. Significance of fractionated irradiation for the biological therapeutic gain of carbon ions. Radiat Prot Dosimetry 2002; 99: 405-8.
37. Mizoe J, Tsujii H, Kamada T, et al. Preliminary results of carbon-ion radiotherapy for advanced head and neck cancer. Int J Radiat Oncol Biol Phys 2000; 46: 691.
38. Schulz-Ertner D, Haberer T, Jäkel O, et al. Radiotherapy for chordomas and low-grade chondrosarcomas of the skull base with carbon ions. Int J Radiat Oncol Biol Phys 2002; 53: 36-42.
39. Russel KJ, Caplan RJ, Laramore GE, et al. Photon versus fast neutron external beam radiotherapy in the treatment of locally advanced prostate cancer: results of a randomized prospective trial. Int J Radiat Oncol Biol Phys 1993; 28: 47-54.
40. Griffin TW, Laramore GE. Neutron radiation and prostate cancer. Int J Radiat Oncol Biol Phys 1995; 33: 231-2.
41. Pickles T, Goodman GB, Fryer CJ, et al. Pion conformal radiation of prostate cancer: results of a randomized study. Int J Radiat Oncol Biol Phys 1998; 43: 47-55.
42. Haraf DJ, Rubin SJ, Sweeney P, et al. Photon neutron mixed-beam radiotherapy of locally advanced prostate cancer. Int J Radiat Oncol Biol Phys 1995; 33: 3-14.
43. Joiner MC, Marples B, Lambin P, et al. Low-dose hypersensitivity: current status and possible mechanisms. Int J Radiat Oncol Biol Phys 2001; 49: 379-89.
44. Skarsgard LD, Hill AA, Acheson DK. Evidence for two forms of substructure in the cell survival curve - mechanisms and clinical consequences. Acta Oncol 1999; 38: 895-902.
45. Turesson I, Bernefors R, Book M, et al. Normal tissue response to low doses of radiotherapy assessed by molecular markers. A study of skin in patients treated for prostate cancer. Acta Oncol 2001; 40: 941-51.
46. Turesson I, Carlsson J, Brahme A, Glimelius B, Zackrisson B, Stenerlöw B and the Swedish Cancer Society Investigation Group. Biological response to radiation therapy. Acta Oncol 2003; 42: 92-106.
47. Suit H. The Gray Lecture 2001: coming technical advances in radiation oncology. Int J Radiat Oncol Biol Phys 2002; 53: 798-809.
48. Swedish Cancer Society. Investigation concerning clinical treatment studies. Cancerfonden, 1999.
49. Mattsson S, Brahme A, Carlsson J, et al. Swedish Cancer Society radiation therapy research investigation. Acta Oncol 2002; 41: 596-603.