Effects of a novel zinc-magnesium formulation on hormones and strength

Journal of Exercise Physiology Online

Volumn 3, Issue 4, 2000, Pages 26-36

  Brilla, L R ^a   Conte, Victor ^b  

^a WESTERN WASHINGTON UNIVERSITY   (United States)

^b BALCO Laboratories   (United States)

Author keywords

Anabolic hormones; IGF I; Muscle; Testosterone; Vitamin B6

Indexed keywords

HORMONE; MAGNESIUM ASPARTATE; PLACEBO; PYRIDOXINE; SOMATOMEDIN C; TESTOSTERONE; UNCLASSIFIED DRUG; ZINC DERIVATIVE; ZINC MONOMETHIONINE ASPARTATE;

ARTICLE; ATHLETE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DYNAMOMETRY; FOOTBALL; HORMONE ACTION; HUMAN; HUMAN EXPERIMENT; MUSCLE FUNCTION; MUSCLE STRENGTH; MUSCLE TRAINING; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; SUPPLEMENTATION; TORQUE;

EID: 0010971605     PISSN: 10979751     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Dorup I, Flyvbjerg A, Everts ME, Clausen T. Role of insulin-like growth factor-1 and growth hormone in growth inhibition induced by magnesium and zinc deficiencies. Br J Nutr 1991:66:505-21.
2. Prasad AS, Mantzoros CS, Beck FW, Hess JW, Brewer GJ. Zinc status and serum testosterone levels of healthy adults. Nutr 1996:12:344-8.
3. Guezennec Y, Leger L, Lhoste F, Aymonod M, Pesquies PC. Hormone and metabolite response to weight-lifting training sessions. Int J Sports Med 1986:7:100-5.
4. Nicklas BJ, Ryan AJ, Treuth MM, Harman SM, Blackman MR, Hurley BF et al. Testosterone, growth hormone and IGF-I responses to acute and chronic resistive exercise in men ages 55-70 years. J Sports Med 1995:16:445-50.
5. Thompson JL, Butterfield GE, Gylfadottir UK, Yesavage J, Marcus R, Hintz RL et al. Effects of human growth hormone, insulin-like growth factor I, diet and exercise on body composition of obese postmenopausal women. J Clin Endocrinol Metab 1998:83:1477-84.
6. Konig D, Weinstock C, Keul J, Northoff H, Berg A. Zinc, iron, and magnesium status in athletes-influence on the regulation of exercise-induced stress and immune function. Exerc Immunol Rev 1998:4:2-21.
7. Cordova A, Navas FJ. Effect of training on zinc metabolism - changes in serum and sweat zinc concentrations in sportsmen. Ann Nutr Metab 1998:42:274-82.
8. Hawley JA, Dennis SC, Lindsay FH, Noakes TD. Nutritional practices of athletes - are they sub-optimal? J Sports Sci 1995:13:S75-81.
9. Carpino A, Sisci D, Aquila S, Beraldi E, Sessa MT, Siciliano L et al. Effects of short-term high-dose testosterone propionate administration on medium molecular-weight proteins of human seminal plasma. Andrologia 1994:29:241-5.
10. Brilla LR, Lombardi VP. Magnesium in sports physiology and performance. In: Kies CV, Driskell JA, editors. Sports Nutrition: Minerals and Electrolytes, An American Chemical Society Monograph. Boca Raton, FL: CRC Press, 1995:139-77.
11. Buchmann AL, Keen C, Commisso J, Killip D, Ou DN, Rognerud CL et al. The effect of a marathon run on plasma and urine mineral and metal concentrations. J Am Coll Nutr 1998:17:124-7.
12. Evans GW, Johnson EC. Effect of iron, vitamin B-6 and picolinic acid on zinc absorption in the rat. J Nutr 1981:111:68-75.
13. Wichnik A, Schroll A, Kollmer WE, Berg D, Wischnik B, Wieshammer E et al. Magnesium aspartate as a cardioprotective agent and adjuvant in tocolysis with betamimetics. Animal experiments on the kinetics and calcium antagonist action of orally administered magnesium aspartate with special reference simultaneous vitamin B administration. Z Geburtshilfe Perinatol, 1982;186:326-34.
14. Clarkson PM, Haymes EM. Exercise and mineral status of athletes - calcium, magnesium, phosphorus, and iron. Med Sci Sports Exerc 1995:27:831-43.
15. Erfurth EM, Hagmar LE, Saaf M, Hall K. Serum levels of insulin-like growth factor I and insulin-like growth factor-binding protein 1 correlate with serum free testosterone and sex hormone binding globulin levels in healthy young and middle-aged men. Clin Endocrinol 1996:44:659-64.
16. Grinspoon S, Corcoran C, Lee K, Burrows B, Hubbard J, Katznelson L et al. Loss of lean body and muscle mass correlates with androgen levels in hypogonadal men with acquired immunodeficiency syndrome and wasting. J Clin Endocrinol Metab 1996:81:4051-8.
17. Hakkinen K, Keskinen KL, Alen M, Komi PV, Kauhanen H. Serum hormone concentrations during prolonged training in elite endurance-trained and strength-trained athletes. Eur J Appl Physiol 1989:59:233-8.
18. McCall GE, Allen DL, Linderman JK, Grindeland RE, Roy RR, Mukku VR et al. Maintenance of myonuclear domain size in rat soleus after overload and growth hormone/IGF-I treatment. J Appl Physiol 1998:84:1407-12.
19. Om A, Chung K. Dietary zinc deficiency alters 5α-reduction and aromatization of testosterone and androgen and estrogen receptors in rat liver. J Nutr 1996:126:842-8.
20. VanLoan MD, Sutherland, B., Lowe NM, Turnland JR, King JC. The effects of zinc depletion on peak force and total work of knee and shoulder extensor and flexor muscles. Int J Sport Nutr 1999:9:125-135.
21. Thissen JP, Ketelslegers JM, Underwood LE. Nutritional regulation of the insulin-like growth factors. Endocr Rev 1994:15:80-101.
22. Corpas E, Blackman MR, Roberson R, Scholfield D, Harman SM. Oral arginine-lysine does not increase growth hormone or insulin-like growth factor-I in old men. J Gerontol 1993:48:M128-33.
23. Ninh NX, Thissen JP, Collette L, Gerard G, Khoi HH, Ketelsleger JM. Zinc supplementation increases growth and circulating insulin-like growth fact I (IGF-I) in growth-retarded Vietnamese children. Am J Clin Nutr 1996:63:514-9.
24. Golf SW, Bender S, Gruttner J. On the significance of magnesium in extreme physical stress. Cardiovasc Drugs Ther 1998:12:197-202.
25. Adams GR, Haddad F. The relationships among IGF-1, DNA content, and protein accumulation during skeletal muscle hypertrophy. J Appl Physiol 1996:81:2509-16.
26. Kraemer WJ, Volek JS, Bush JA, Putukian, Sebastianelli WJ. Hormonal responses to consecutive days of heavy-resistance exercise with or without nutritional supplementation. J Appl Physiol 1998:85:1544-55.