Seropositivity to Helicobacter pylori and CagA protein in schoolchildren of different ages living in urban and rural areas in southern Estonia

European Journal of Gastroenterology and Hepatology

Volumn 12, Issue 1, 2000, Pages 97-101

  Vorobjova, Tamara ^b   Grünberg, Heli ^c   Oona, Marje ^c   Maaroos, Heidi Ingrid ^c   Nilsson, Ingrid ^c   Wadström, Torkel ^c   Covacci, Antonello ^a   Uibo, Raivo ^c  

^a CHIRON VACCINES   (Italy)

^b UNIVERSITY OF TARTU   (Estonia)

^c NONE

Author keywords

CagA antibodies; Enzyme linked immunosorbent assay; Helicobacter pylori; Schoolchildren

Indexed keywords

BACTERIAL PROTEIN; IMMUNOGLOBULIN G ANTIBODY;

ADOLESCENT; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDEMIOLOGICAL DATA; ESTONIA; FEMALE; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; HUMAN; MALE; NORMAL HUMAN; POPULATION RESEARCH; PRIORITY JOURNAL; RURAL AREA; SCHOOL CHILD; URBAN AREA;

EID: 0010389840     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-200012010-00018     Document Type: Article

References (46)

1. 1 Sipponen P, Kekki M, Siurala M. The Sydney System: epidemiology and natural history of chronic gastritis. J Gastroenterol Hepatol 1991; 6:244-251.
2. 2 Parsonnet J, Friedman GD, Vandersteen DP, Chang Y, Vogelman JH, Orentreich N, et al. Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 1991; 325:1127-1131.
3. 3 Sipponen P. Gastric cancer - a long-term consequence of Helicobacter pylori infection? Scand J Gastroenterol 1994; 29(suppl 201):24-27.
4. 4 Rugge M, Cassaro M, Leandro G, Baffa R, Avellini C, Bufo P, et al. Helicobacter pylori in promotion of gastric carcinogenesis. Dig Dis Sci 1996; 41:950-955.
5. 5 Crabtree JE, Taylor JD, Wyatt JI, Heatley RV, Shallcross TH, Tompkins DS, et al. Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration and gastric pathology. Lancet 1991; 338:332-335.
6. 6 Forman D. Helicobacter pylori and gastric cancer. Scand J Gastroenterol 1996; 31(suppl 214):31-33.
7. 7 Kuipers EJ, Pérez-Pérez GI, Meuwissen SGM, Blaser MJ. Helicobacter pylori and atrophic gastritis: importance of the CagA status. J Natl Cancer Inst 1995; 87:1777-1780.
8. 8 Parsonnet J, Friedman GD, Orentreich N, Vogelman H. Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection. Gut 1997; 40:297-301.
9. 9 Graham DY, Klein PD, Evans DG, Fiedorek C, Evans DJ, Adam E, Malaty HM. Helicobacter pylori: epidemiology, relationship to gastric cancer and the role of infants in transmission. Eur J Gastroenterol Hepatol 1992; 4(suppl 1):S1-S6.
10. 10 Blaser MJ, Chyou PH, Nomura A. Age at establishment of Helicobacter pylori infection and gastric carcinoma, gastric ulcer and duodenal ulcer risk. Cancer Res 1995; 55:562-565.
11. 11 Li YY, Hu PJ, Liu DQ, Lin HL, Chen MH, Hazell SL, et l. Helicobacter pylori and gastric cancer: an endoscopic survey of healthy children in high and low risk areas for gastric cancer in China [Abstract]. Gut 1995; 37(suppl 1):A38.
12. 12 Sherman PM, Hunt RH. Why guidelines are required for the treatment of Helicobacter pylori infection in children. Clin Invest Med 1996; 19:362-367.
13. 13 Vorobjova T, Kisand K, Haukanomm A, Maaroos H-I, Wadström T, Uibo R. The prevalence of Helicobacter pylori antibodies in a population from Southern Estonia. Eur J Gastroenterol Hepatol 1994; 6:529-533.
14. 14 Vorobjova T, Nilsson I, Kull K, Maaroos H-I, Covacci A, Wadström T, Uibo R. CagA protein seropositivity in a random sample of adult population and gastic cancer patients in Estonia. Eur J Gastroenterol Hepatol 1998; 10:41-46.
15. 15 Lelwala-Guruge J, Schalén C, Nilsson I, Ljungh Å, Tyszkiewicz T, Wikander M, Wadström T. Defection of antibodies to Helicobacter pylori cell surface antigens. Scand J Infect Dis 1990; 22:457-465.
16. 16 Xiang Z, Bugnoli M, Ponzetto A, Morgando A, Figura N, Covacci A, et al. Detection in an enzyme immunoassay of an immune response to a recombinant fragment of the 128 kilodalton protein (CagA) of Helicobacter pylori. Eur J Clin Microbiol Infect Dis 1993; 12:739-745.
17. 17 Brown RA, Swanson Beck J. Statistics on microcomputers: a non-algebraic guide to the appropriate use of statistical packages in biomedical research and pathology laboratory practice. 6. Statistical methods for diagnostic tests. J Clin Pathol 1989; 42:225-230.
18. 18 Maaroos H-I, Rägo T, Sipponen P, Siurala M. Helicobacter pylori and gastritis in children with abdominal complaints. Scand J Gastroenterol 1991; 26(suppl 186):95-99.
19. 19 Granstrom M, Tindberg Y, Blennow M. Seroepidemiology of Helicobacter pylori infection in a cohort of children monitored from 6 months to 11 years of age. J Clin Microbiol 1997; 35:468-470.
20. 20 Hornemann F, Nilius M, Malfertheiner P, Bartmann P. Seroprevalence of Helicobacter pylori in German infants and children. Helicobacter 1997; 2:176-179.
21. 21 Roosendaal R, Kuipers EJ, Buitenwerf J, Van Uffelen C, Meuwissen SG, Van Kamp GJ, Vandenbroucke-Grauls CM. Helicobacter pylori and the birth cohort effect: evidence of a continuous decrease of infection rates in childhood. Am J Gastroenterol 1997; 92:1480-1482.
22. 22 O'Donohoe JM, Sullivan PB, Scott R, Rogers T, Brueton MJ, Barltrop D. Recurrent abdominal pain and Helicobacter pylori in a community-based sample of London children. Acta Paediatr 1996; 85:961-964.
23. 23 Okuda M, Tanaka T, Nakamoto H, Katai A, Nakata H, Koike M, Miyamoto H. Helicobacter pylori infection in childhood: H. pylori isolation rate in gastric juice in relation to positive serum antibody rates. J Gastroenterol 1996; 31(suppl 9):6-8.
24. 24 Gurakan F, Kocak N, Yuce A. Helicobacter pylori serology in childhood. Turk J Pediatr 1996; 38:329-334.
25. 25 Figura N. Helicobacter pylori exotoxins and gastroduodenal diseases associated with cytotoxic strain infection. Aliment Pharmacol Ther 1996; 10(suppl 1):79-96.
26. 26 Oderda G, Figura N, Bayeli PF, Basagni C, Bugnoli M, Armellini D, et al. Serologic IgG recognition of Helicobacter pylori cytotoxin-associated protein, peptic ulcer and gastroduodenal pathology in childhood. Eur J Gastroenterol Hepatol 1993; 5:695-699.
27. 27 Doermann HP, Birac C, Lamireau T, Mégraud F. Distribution of the cagA gene in Helicobacter pylori strains isolated from children [Abstract]. Gut 1995;37(supp 1):A25.
28. 28 Vandenborre C, Cadranel S, Butzler J-P, Glupczynski Y. Serum reactivity to Helicobacter pylori antigens assessed by Helico Blot 2.0 in H. pylori-positive children from different ethnic groups [Abstract]. Gut 1995; 37(suppl 1):A79.
29. 29 Rautelin H, Karhukorpi J, Lindahal H, Kolho KL, Kartunen R. Prevalence of CagA-positive H. pylori strains in children [Abstract]. Gut 1996; 39(suppl 2):A51.
30. 30 Czkwianianc E, Chmiela M, Lawnik M, Planeta-Malecka I, Rudnicka W. Serodiagnosis of Helicobacter pylori in children with gastroduodenitis. Cent Eur J Immunol 1997; 22:240-247.
31. 31 Gzyl A, Berg DE, Dzierzanowska D. Epidemiology of cagA/vacA genes in H. pylori isolated from children and adults in Poland. J Physiol Pharmacol 1997; 48:333-343.
32. 32 Elitsur Y, Neace C. The prevalence of Cag-A/VacA H. pylori strains in asymptomatic children of West Virginia [Abstract]. Gut 1997; 41(suppl 1):A67.
33. 33 Karczewska E, Kacka K, Bielanski W, Plonka M, Zarzycki D, Konturek SJ, Kleanthous H. The seroprevalence of IgG antibodies to H. pylori CagA protein in asymptomatic children assessed by Helico Blot 2.0 and ELISA method [Abstract]. Gut 1997; 41(suppl 1):A70.
34. 34 Lopez-Brea M, Alarcon T, Martinez MJ, Sánchez I, Domingo D, Sanz JC. Cag-A gene, age and serological findings in H. pylori infected Spanish children (Abstract). Gut 1997; 41(suppl 1):A69.
35. 35 Mitchell HM, Li YY, Hu PJ, Liu Q, Chen M, Du GG, et al. Epidemiology of Helicobacter pylori in southern China: identification of early childhood as the critical period for acquisition. J Infect Dis 1992; 166:149-153.
36. 36 Klein PD, Graham DY, Gaillour A, Opekun AR, Smith EO. Water source as risk factor for Helicobacter pylori infection in Peruvian children. Gastrointestinal Physiology Working Group. Lancet 1991; 337:1503-1506.
37. 37 Mendall MA, Goggin PM, Molineaux N, Levy J, Toosy T, Strachan D, Northfield TC. Childhood living conditions and Helicobacter pylori seropositivity in adult life. Lancet 1992; 339:896-897.
38. 38 Neale KR, Logan RP. The epidemiology and transmission of Helicobacter pylori infection in children. Aliment Pharmacol Ther 1995; 9(suppl 2):77-84.
39. 39 Ashorn M, Miettien A, Ruuska T, Laippala P, Mäki M. Seroepidemiological study of Helicobacter pylori infection in infancy. Arch Dis Child 1996; 74:F141-F142.
40. 40 Rowland M, Drumm B. Clinical significance of Helicobacter infection in children. Br Med Bull 1998; 54:95-103.
41. 41 Lindkvist P, Tammur R, Nilsson I, Wrtline B, Giesecke J. Helicobacter pylori infection in Estonia - a three-year follow-up of children from birth [Abstract]. Gut 1999; 45(suppl 3):A45.
42. 42 Lindkvist P, Asrat D, Nilsson I, Tsega E, Olsson GL, Wretlind B, Giesecke J. Age at acquisition of Helicobacter pylori infection: comparison of a high and a low prevalence country. Scand J Infect Dis 1996; 28:181-184.
43. 43 Sipponen P, Kosunen TU, Samloff IM, Heinonen OP, Siurala M. Rate of Helicobacter pylori acquisition among Finnish adults. A 15-year follow-up. Scand J Gastroenterol 1996; 31:229-232.
44. 44 Sipponen P. Helicobacter pylori gastritis - epidemiology. J Gastroenterol 1997; 32:273-277.
45. 45 Maaroos H-I, Villako K, Sipponen P, Kekki M, Siurala M, Tammur R, et al. Helicobacter pylori and chronic gastritis in random population sample of Estonia. Arch Pathol 1990; 10:9-11.
46. 46 Mégraud F, Brassens-Rabbé M-P, Denis F, Belbouri A, Hoa DQ. Seroepidemiology of Campylobacter infection in various populations. J Clin Microbiol 1989; 27:1870-1873.