Deletions at the carboxyl terminus of vaccinia DNA topoisomerase affect DNA binding and enhance distributivity in DNA relaxation

Biochemistry

Volumn 36, Issue 13, 1997, Pages 3909-3916

  Wang, Li Kai ^a   Shuman, Stewart ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; MAGNESIUM; SODIUM CHLORIDE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DELETION MUTANT; DNA BINDING; DNA CLEAVAGE; DNA DENATURATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ESCHERICHIA COLI; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; VACCINIA VIRUS;

AMINO ACID SEQUENCE; BINDING SITES; DNA; DNA TOPOISOMERASES, TYPE I; DNA-BINDING PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; KINETICS; MAGNESIUM; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEIC ACID CONFORMATION; SEQUENCE DELETION; SODIUM CHLORIDE; SUBSTRATE SPECIFICITY; VACCINIA VIRUS;

EID: 0010264286     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi962754p     Document Type: Article

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