Improvement of thermal stability of a diagnostic enzyme, Streptomyces cholesterol oxidase, by random and site-directed mutageneses and a structural interpretation

Progress in Biotechnology

Volumn 15, Issue C, 1998, Pages 295-302

  Murooka, Y ^a   Nishiya, Y ^b   Toyama, M ^a   Aoike, M ^a   Yamashita, M ^a   Hirayama, N ^c  

^a OSAKA UNIVERSITY   (Japan)

^b TOYOBO CO LTD   (Japan)

^c TOKAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0009711712     PISSN: 09210423     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0921-0423(98)80044-0     Document Type: Chapter

References (11)

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4. Nomura N., Choi K.-P., Yamashita M., Yamamoto H., and Murooka Y. J. Ferment. Bioeng. 79 (1995) 410-416
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6. Li J., Vrielink A., Brick P., and Blow D.M. Biochemistry 32 (1993) 11507-11515
7. Nishiya Y., Harada N., Teshima S.-I., Yamashita M., Fujii I., Hirayama N., and Murooka Y. Protein Eng. 10 (1997) 231-235
8. Allain C.C., Poon L.S., Chan C.G.S., Richmond W., and Fu P.C. Clin. Chem. 20 (1974) 470-475
9. Needleman S.B., and Wunsch C.D. J. Mol. Biol. 48 (1970) 443-453
10. Bernstein F.C., Koetzle T.F., Williams G.J.B., Meyer E.F., Brice M.D., Rodgers J.R., Kennard O., Shimanouchi T., and Tasumi Y. J. Mol. Biol. 112 (1977) 535-542
11. Fujii I., Hirayama N., Yamashita M., and Murooka Y. Abstract Book of Annual Meeting of Nippon Seibutsu Kougaku (1994), Society for Fermentation and Bioengineering, Japan 106