Structure-activity relationship analysis of 4'-bromo-[1,1'-biphenyl]-4- yl 4-X-phenyl methanone derivatives and activity against mycobacterium tuberculosis

Arzneimittel-Forschung/Drug Research

Volumn 49, Issue 12, 1999, Pages 1025-1029

  De Souza, Ana O ^a   Alderete, Joel B ^b   Schimidt, Fernando ^a   Sato, Daisy N ^c   Durán, Nelson ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b UNIVERSITY OF CONCEPCIÓN   (Chile)

^c INSTITUTO ADOLFO LUTZ   (Brazil)

Author keywords

Antituberculosis drugs; Biphenyl methanone derivatives, antimycobacterial activity, principal component analysis, synthesis

Indexed keywords

4' BROMO [1,1' BIPHENYL] 4 YL 4 PHENYLMETHANONE; METHANOL DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; ARTIFICIAL NEURAL NETWORK; DERIVATIZATION; DRUG EFFECT; DRUG SYNTHESIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATION REDUCTION REACTION; PRINCIPAL COMPONENT ANALYSIS; STRAIN DIFFERENCE; STRUCTURE ACTIVITY RELATION; TUBERCULOSIS;

EID: 0006724765     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1300545     Document Type: Article

References (25)

1. The World Health Report, World Health Organization, Geneva, Switzerland (1998)
2. Rastogi, N., Labrousse, V., Seng Goh, K., Curr. Microbiol. 33, 167 (1996)
3. De Conti, R., Gimenez, S. M. N., Haun, M. et al., Eur. J. Med. Chem. 31, 1 (1996)
4. Collins, L. A., Franzblau, S. G., Antimicrob. Agents Chemother. 41, 1004 (1997)
5. Wold, S., Esbensen, K., Geladi, P., Chem. Intelligent Lab. Sys. 2, 37 (1987)
6. De Souza, A. D., Alderete, J. B., Sato, D. N. et al., Proc. 14th Int. Conference Phys. Org. Chem., Florianopolis, S.C., Brazil 14, 184 (1998)
7. Costa, M. C. A., Gaudio, A. C., Takahata, Y., J. Mol. Struct. (Theochem) 394, 291 (1997)
8. Hansch, C., Leo, A., Hoeckman, D., in: Exploring QSAR, pp. 217-304, ACS Professional Reference Book, Washington, DC (1995)
9. Karelson, K., Lobanov, V. S., Katritzky, A. R., Chem. Ber. 96, 1027 (1996)
10. Dewar, M. J. S., Zoebisch, E. G., Healy, E. F. et al., J. Am. Chem. Soc. 107, 3902 (1985)
11. Gough, K. M., Belohorcova, K., Kaiser, K. L. E., Sci. Total. Environm. 142, 179 (1994)
12. Schalkoff, R. in: Pattern Recognition statistical, structural and neural approaches. John Wiley & Sons, New York (1992)
13. Oinuma, H., Miyake, K., Yamanaka, M. et al., J. Med. Chem. 33, 905 (1988)
14. Isu, Y., Nagashima, U., Aoyama, T. et al., J. Chem. Inform. Comp. Sci. 36, 286 (1996)
15. Parr, R. G., Pearson, R. G., J. Am. Chem. Soc. 105, 7512 (1983)
16. Brown, R. E., Simas, A. M., Theor. Chim. Acta 62, 1 (1982)
17. Abraham, M. H., Mc Gowan, J. C., Chromatografia, 23, 243 (1987)
18. Cartier, A., Rivail, J. L., Chem. Intelligent Lab. Sys. 1, 335 (1987)
19. Stewart, J. J. P., MOPAC 6.0 manual. Frank J. Seiler Research Laboratory, United States Air Force Academy, Colorado Springs, CO
20. Danon, Y., WinNN 0.97 program, copyright 1993-1995
21. Yajko, D. M., Madej, J. J., Lancaster, M. V. et al., J. Clin. Microbiol. 33, 2324 (1995)
22. Aoyama, T., Suzuki, Y., Ichikawa, H., J. Med. Chem. 33, 2583 (1990)
23. Ahmed, S. A., Gogal, R. M., Walsh, J. E., J. Immunol.. Meth. 170, 211 (1994)
24. Klopman, G., Fercu, D., Jacob, J., J. Chem. Phys. 204, 181 (1996)
25. Karash, N., Terzioglu, N., Gürsoy, A., Arzneim.-Forsch./Drug Res. 48(II), 758 (1998)