Chapter 12 Drug Delivery Applications

Current Topics in Membranes and Transport

Volumn 44, Issue C, 1997, Pages 449-475

  Sorgi, Frank L ^a   Huang, Leaf ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0006596120     PISSN: 00702161     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0070-2161(08)60216-6     Document Type: Article

References (90)

1. Arvinte T., Wahl P., and Nicolau C. Low pH fusion of mouse liver nuclei with liposomes bearing covalently bound lysozyme. Biochim. Biophys. Acta 899 (1987) 143-150
2. Bennett C.F., Chiang M.Y., Chan H., Shoemaker J.E., and Mirabelli C.K. Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides. Mol. Pharmacol. 41 (1992) 1023-1033
3. Bennett D.E., Lamparski H., and O'Brien D.F. Photosensitive liposomes. J. Liposome Res. 4 (1994) 331-348
4. Bentz J., Ellens H., Lai M.Z., and Szoka Jr. F.C. On the correlation between phase and contact-induced destabilization of phosphatidyl ethanolamine containing membranes. Proc. Natl. Acad. Sci. U. S. A. 82 (1985) 5742-5745
5. Capecchi M.R. High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell 22 (1980) 479-488
6. Caplen N.J., Alton E.W.F.W., Middleton P.G., Dorin J.R., Stevenson B.J., Gao X., Durham S.R., Jeffery P.K., Hodson M.E., Coutelle C., Huang L., Porteous D.J., Williamson R., and Geddes D.M. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nature Med. 1 (1995) 39-46
7. Cestaro B., Cazzola R., and Viani P. pH-sensitive liposomes: Structural characterization and possible therapeutic applications. J. Liposorne Res. 3 (1993) 563-574
8. Cevc G., and Marsh D. Hydration of noncharged lipid membranes: Theory and experiments with phosphatidylethanolamines. Biophys. J. 47 (1985) 21-31
9. Cheng K.H. Headgroup hydration and motional order of lipids in lamellar liquid crystalline and inverted hexagonal phases of unsaturated phosphatidylethanolamine-a time-resolved fluorescence study. Chem. Phys. Lipids 53 (1990) 191-202
10. Chu C.-J., and Szoka Jr. F.C. pH-sensitive liposomes. J. Liposome Res. 4 (1994) 361-395
11. Collins D., and Huang L. Cytotoxicity of diphtheria toxin A fragment to toxin-resistant murine cells delivery by pH-sensitive immunoliposomes. Cancer Res. 46 (1987) 3431-3435
12. Collins D., Connor J., Ting-Beall H.-P., and Huang L. Proton and divalent cations induce synergistic but mechanistically different destabilizations of pH-sensitive liposomes composed of dioleoyl phosphatidylethanolamine and oleic acid. Chem. Phys. Lipids 55 (1990) 339-349
13. Collins D., Litzinger D., and Huang L. Structural and functional comparisons of pH-sensitive liposomes composed of phosphatidyl ethanolamine and three different diacylsuccinylglycerols. Biochim. Biophys. Acta 1025 (1990) 234-242
14. Connor J., and Huang L. Efficient cytoplasmic delivery of a fluorescent dye by pH-sensitive immunoliposomes. J. Cell Biol. 101 (1985) 582-589
15. Connor J., and Huang L. pH-sensitive immunoliposomes as an efficient and target-specific carrier for antitumor drugs. Cancer Res. 46 (1986) 3431-3435
16. Connor J., Yatvin M.B., and Huang L. pH-sensitive liposomes: Acid-induced liposome fusion. Proc. Natl. Acad. Sci. U. S. A. 81 (1984) 1715-1718
17. Connor J., Norley N., and Huang L. Biodistribution of pH-sensitive liposomes. Biochim. Biophys. Acta 884 (1986) 474-481
18. Cristiano R.J., and Curiel D.T. Strategies to accomplish gene delivery via the receptor-mediated endocytosis pathway. Cancer Gene Ther. 3 (1996) 49-57
19. Crook K., McLachlan G., Stevenson B.J., and Porteous D.J. Plasmid DNA molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolization. Gene Ther. 3 (1996) 834-839
20. Cullis P.R., and de Kruijff B. Lipid polymorphism and the functional roles of lipids in biological membranes. Biochim. Biophys. Acta 559 (1979) 399-420
21. de Kruiff B. Polymorphic regulation of membrane lipid composition. Nature (London) 329 (1987) 587-588
22. Egilmez N.K., Iwanuma Y., and Bankert R.B. Evaluation and optimization of different cationic liposome formulations for in vivo gene transfer. Biochem. Biophys. Res. Commun. 221 (1996) 169-173
23. Eibl H. Phospholipids as functional constituents of biomembranes. Angew. Chem. Int. Ed. Engl. 23 (1984) 257-271
24. Ellens H., Bentz J., and Szoka Jr. F.C. pH-induced destabilization of phosphatidylethanolamine-containing liposomes: Role of bilayer contact. Biochemistry 23 (1985) 1532-1538
25. Farhood H., Gao X., Son K., Yang Y.-Y., Lazo J.S., and Huang L. Cationic liposomes for direct gene transfer in therapy of cancer and other diseases. Ann. N. Y. Acad. Sci. 716 (1994) 23-35
26. Farhood H., Serbina N., and Huang L. The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim. Biophys. Acta 1235 (1995) 289-295
27. Felgner P.L., and Ringold G.M. Cationic-liposome mediated transfection. Nature (London) 337 (1989) 387-388
28. Felgner P.L., Gadek T.R., Holm M., Roman R., Chan H.W., Wenz M., Northrop J.P., Ringold G.M., and Danielsen M. Lipofection: A highly efficient, lipid-mediated DNA transfection procedure. Proc. Natl. Acad. Sci. U. S. A. 84 (1987) 7413-7417
29. Felgner J.H., Kumar R., Sridhar C.N., Wheeler C.J., Tsai Y.J., Border R., Ramsey P., Martin M., and Felgner P.L. Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J. Biol. Chem. 269 (1994) 2550-2561
30. Finkelstein M.C., and Weissmann G. Targetting of liposomes. In: Knight C.G. (Ed). Liposomes: From Physical Structure to Therapeutic Applications (1981), Elsevier/North-Holland Biomedical Press, Amsterdam 443-464
31. Friend D.S., Papahadjopoulos D., and Debs R.J. Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes. Biochim. Biophys. Acta 1278 (1996) 41-50
32. Fritz J.D., Herweijer H., Zhang G., and Wolff J.A. Gene transfer into mammalian cells using histone-condensed plasmid DNA. Human Gene Ther. 7 (1996) 1395-1404
33. Gangé J., Stamatatos L., Diacovo T., Hui S.W., Yeagle P.L., and Silvius J.R. Physical properties and surface interactions of bilayer membranes containing N-methylated phosphatidylethanolamines. Biochemistry 24 (1985) 4400-4408
34. Gao X., and Huang L. Potentiation of cationic liposome-mediated gene delivery by polycations. Biochemistry 35 (1996) 1027-1036
35. Gershon H., Ghirlando R., Guttman S.B., and Minsky A. Mode of formation and structural features of DNA-cationic liposome complexes used for transfection. Biochemistry 32 (1993) 7143-7151
36. Gould-Fogerite S., Mazurkiewicz J.E., Raska K., Voelkerding K., Lehman J.M., and Mannino R.J. Chimerasome-mediated gene transfer in vitro and in vivo. Gene 84 (1989) 429-438
37. Gruner S.M., Cullis P.R., Hope M.J., and Tilcock C.P.S. Lipid polymorphism: The molecular basis of nonbilayer phases. Annu. Rev. Biophys. Chem. 14 (1985) 211-238
38. Gustafsson J., Arvidson G., Karlsson G., and Almgren M. Complexes between cationic liposomes and DNA visualized by cryo-TEM. Biochim. Biophys. Acta 1235 (1995) 305-312
39. Hawley-Nelson P., Ciccarone V., Gebeyehu G., and Jessee J. Lipofectamine reagent: A new, higher efficiency polycationic liposome transfection reagent. Focus 15 (1993) 73-79
40. Ho R.J.Y., Rouse B.T., and Huang L. Target-sensitive immunoliposomes: Preparation and characterization. Biochemistry 25 (1986) 5500-5506
41. Hofland H.E.J., Shephard L., and Sullivan S.M. Formation of stable cationic lipid/DNA complexes for gene transfer. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 7305-7309
42. Huang L. Target-sensitive liposomes. J. Liposome Res. 4 (1994) 397-412
43. Hug P., and Sleight R.G. Liposomes for the transformation of eukaryotic cells. Biochim. Biophys. Acta 1097 (1991) 1-17
44. Jääkeläinen I., Mönkkönen J., and Urtti A. Oligonucleotide-cationic liposome interactions: A physiochemical study. Biochim. Biophys. Acta 1195 (1994) 115-123
45. Jarnagin W.R., Debs R.J., Wang S.-S., and Bissell D.M. Cationic lipid-mediated transfection of liver cells in primary culture. Nucleic Acids Res. 20 (1992) 4205-4211
46. Kao G.Y., Chang L.-J., and Allen T.M. Use of targeted cationic liposomes in enhanced DNA delivery to cancer cells. Cancer Gene Ther. 3 (1996) 250-256
47. Knight C.G. Hydrophobic pro-drugs in liposomes. In: Knight C.G. (Ed). Liposomes: From Physical Structure to Therapeutic Applications (1981), Elsevier/North-Holland Biomedical Press, Amsterdam 381-390
48. Lamparski H., Liman U., Barry J.A., Frankel D.A., Ramaswami V., Brown M.F., and O'Brien D.F. Photoinduced destabilization of liposomes. Biochemistry 31 (1992) 685-694
49. Lee E.R., Marshall J., Siegel C.S., Jiang C., Yew N.S., Nichols M.R., Nietupski J.B., Ziegler R.J., Lane M.B., Wang K.X., Wan N.C., Scheule R.K., Harris D.J., Smith A.E., and Cheng S.H. Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung. Human Gene Ther. 7 (1996) 1701-1717
50. Lee R.J., and Huang L. Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell specific gene transfer. J. Biol. Chem. 271 (1996) 8481-8487
51. Legendre J.Y., and Szoka F.C. Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: Comparison with cationic liposomes. Pharm. Res. 9 (1992) 1235-1242
52. Legendre J.Y., and Szoka F.C. Liposomes for gene therapy. In: Puisieux F., Couvreur P., Delattre J., and Devissaguel J.-P. (Eds). Liposomes: New Systems and New Trends in Their Applications (1995), Editions de Santé, Paris 667-692
53. Leventis R., Diavoco T., and Silvius J. pH-dependent stability and fusion of liposomes combining protonable double chain amphiphiles with phosphatidyl ethanolamine. Biochemistry 26 (1987) 3267-3276
54. Litzinger D.C., and Huang L. Phosphatidylethanolamine liposomes: Drug delivery, gene transfer and immunodiagnostic applications. Biochim. Biophys. Acta 1113 (1992) 201-227
55. Litzinger D.C., Brown J.M., Wala I., Kaufman S.A., Van G.Y., Farrell C.L., and Collins D. Fate of cationic liposomes and their complex with oligonucleotide in vivo. Biochim. Biophys. Acta 1281 (1996) 139-149
56. Liu D., and Huang L. Role of cholesterol in the stability of pH-sensitive, large unilamellar liposomes prepared by the detergent-dialysis method. Biochim. Biophys. Acta 981 (1989) 254-260
57. Liu D., and Huang L. pH-sensitive, plasma-stable liposomes with relatively prolonged residence in circulation. Biochim. Biophys. Acta 1022 (1990) 348-354
58. Liu D., and Huang L. Interaction of pH-sensitive liposomes with blood components. J. Liposome Res 4 (1994) 121-141
59. Liu D., Huang L., Moore M.A., Amantharamaiah G.M., and Segrest J.P. Interactions of serum proteins with dioleoylphosphatidylethanolamine and oleic acid: High-density lipoprotein, apolipoprotein A1, and amphipathic peptides stabilize liposomes. Biochemistry 29 (1990) 3637-3643
60. Machy P., and Leserman L.D. Small liposomes are better than large liposomes for specific drug delivery in vitro. Biochim. Biophys. Acta 730 (1983) 313-320
61. Malone R.W., Felgner P.L., and Verma I.M. Cationic liposome-mediated RNA transfection. Proc. Natl. Acad. Sci. U. S. A. 86 (1989) 6077-6081
62. Miller C.R., Bennett D.E., Chang D.Y., and O'Brien D.F. Effect of liposomal composition on photoactivated liposome fusion. Biochemistry 35 (1996) 11782-11790
63. Minsky A., Ghiriando R., and Gershon H. Structural features of DNA-cationic liposome complexes and their implications for transfection. In: Lasic D.D., and Barenholz Y. (Eds). Nonmedical Applications of Liposomes: From Gene Delivery and Diagnostics to Ecology (1996), CRC Press, Boca Raton, FL. 7-30
64. Pinnaduwage P., and Huang L. Stable target-sensitive immunoliposomes. Biochemistry 31 (1992) 2850-2855
65. Reimer D.L., Zhang Y., Kong S., Wheeler J.J., Graham R.W., and Bally M.B. Formation of novel hydrophobic complexes between cationic lipids and plasmid DNA. Biochemistry 34 (1995) 12877-12883
66. Rose J.K., Buonocore L., and Whitt M.A. A new cationic liposome reagent mediating nearly quantitative transfection of animal cells. Biotechniques 10 (1991) 520-525
67. Schneider M. Liposomes as drug carriers: 10 years of research. In: Buri P., and Gumma A. (Eds). Drug Targeting (1985), Elsevier Biomedical Division, Amsterdam 119-134
68. Schreier H., and Sawyer S.M. Liposomal DNA vectors for cystic fibrosis gene therapy: Current applications, limitations, and future directions. Adv. Drug Delivery Rev. 19 (1996) 73-87
69. Sells M.A., Li J., and Chernoff J. Delivery of protein into cells using polycationic liposomes. Biotechniques 19 (1995) 72-78
70. Smith J.G., Walzem R.L., and German J.B. Liposomes as agents of DNA transfer. Biochim. Biophys. Acta 1154 (1993) 327-340
71. Sorgi F.L., and Huang L. Large scale production of DC-Chol liposomes by microfluidization. Int. J. Pharm. 144 (1996) 131-139
72. Sternberg B. Liposome Technology. 2nd ed. I (1992), CRC Press, Boca Raton, FL. 363-383
73. Sternberg B., Sorgi F.L., and Huang L. New structures in complex formation between DNA and cationic liposomes visualized by freeze-fracture electron microscopy. FEBS Lett. 356 (1994) 361-366
74. Steward M.J., Plautz G.E., Buono L.D., Yang Z.Y., Xu L., Gao X., Huang L., Nabel E.G., and Nabel G.J. Gene transfer in vivo with DNA-liposome complexes: Safety and acute toxicity in mice. Human Gene Ther. 3 (1992) 267-275
75. Straubinger R.M., Duzgunes N., and Papahadjopolos D. pH-sensitive liposomes mediate cytoplasmic delivery of encapsulated macromolecules. FEBS Lett. 179 (1985) 148-154
76. Tate M.W., Eikenberry E.F., Turner D.C., Shyamsunder E., and Gruner S.M. Nonbilayer phases in membrane lipids. Chem. Phys. Lipids 57 (1991) 147-164
77. Torchilin V.P. Liposomes as targetable drug carriers. CRC Crit. Rev. Ther. Drug Carrier Systems 2 (1986) 65-115
78. Torchilin V.P., Omelyanenko V.G., and Lukanov A.N. Temperature-dependent aggregation of pH sensitive phosphatidyl ethanolamine-oleic acid-cholesterol liposomes as measured by fluorescent spectroscopy. Anal. Biochem. 207 (1992) 109-113
79. Torchilin V.P., Zhou F., and Huang L. pH-sensitive liposomes. J. Liposome Res. 3 (1993) 201-255
80. Tycko B., and Maxfield F.R. Rapid acidification of endocytic vesicles containing α2-macroglobulin. Cell 28 (1982) 643-651
81. Vigneron J.-P., Oudrhiri N., Fauquet M., Vergely L., Bradley J.-C., Basseville M., Lehn P., and Lehn J.-M. Guanidium-cholesterol cationic lipids: Efficient vectors for the transfection of eukaryotic cells. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 9682-9686
82. Vitiello L., Chonn A., Wasserman J.D., Duff C., and Worton R.G. Condensation of plasmid DNA with polylysine improves liposome-mediated gene transfer into established and primary muscle cells. Gene Ther. 3 (1996) 396-404
83. Wang C.-Y., and Huang L. pH-sensitive immunoliposomes mediate target-cell-specific delivery and controlled expression of a foreign gene in mouse. Proc. Natl. Acad. Sci. U. S. A. 84 (1987) 7851-7855
84. Wang C.-Y., and Huang L. Plasmid DNA adsorbed to pH-sensitive liposomes efficiently transforms the target cells. Biochem. Biophys. Res. Commun. 147 (1987) 980-985
85. Wang C.-Y., and Huang L. Highly efficient DNA delivery mediated by pH-sensitive immunoliposomes. Biochemistry 28 (1989) 9508-9514
86. Wong F.M.P., Reimer D.L., and Bally M.B. Cationic lipid binding to DNA: Characterization of complex formation. Biochemistry 35 (1996) 5756-5763
87. Wrobel I., and Collins D. Fusion of cationic liposomes with mammalian cells occurs after endocytosis. Biochim. Biophys. Acta 1235 (1996) 296-304
88. Xu Y., and Szoka F.C. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 35 (1996) 5616-5623
89. Zabner J., Fasbender A.J., Moninger T., Poellinger K.A., and Welsh M.J. Cellular and molecular barriers to gene transfer by a cationic lipid. J. Biol. Chem. 270 (1995) 18997-19007
90. Zhou X., and Huang L. DNA transfection mediated by cationic liposomes containing lipopolylysine: Characterization and mechanism of action. Biochim. Biophys. Acta 1189 (1994) 195-203