Liposomal DNA vectors for cystic fibrosis gene therapy. Current applications, limitations, and future directions

Advanced Drug Delivery Reviews

Volumn 19, Issue 1, 1996, Pages 73-87

  Schreier, Hans ^a   Sawyer, Susan M ^b,c  

^a Advanced Therapies Inc   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

Cationic liposome; Clinical trial; Cystic fibrosis; Gene therapy; Plasmid

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; DNA; DRUG PRODUCTS; ENZYMES; GENES; METABOLISM; PHARMACOKINETICS; TOXICITY;

CYSTIC FIBROSIS; GENE THERAPY; IBUPROFEN; LIPOSOMES; PLASMID; TRANSFECTION; URIDINE TRIPHOSPHATE;

DRUG THERAPY;

2,3 DIOLEOYLOXY N [2 (SPERMINECARBOXAMIDE)ETHYL] N,N DIMETHYL 1 PROPANAMMONIUM TRIFLUOROACETATE; AMILORIDE; CATION; COMPLEMENTARY DNA; DIOLEOYLPHOSPHATIDYLCHOLINE; DORNASE ALFA; IBUPROFEN; LIPOFECTAMINE; LIPOFECTIN; LIPOSOME; NONSTEROID ANTIINFLAMMATORY AGENT; NOSE SPRAY; PLASMID DNA; TRANSMEMBRANE CONDUCTANCE REGULATOR; TRIMETHYLAMMONIUM SALT DERIVATIVE; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE;

AEROSOL; CHLORIDE TRANSPORT; CLINICAL PROTOCOL; CLINICAL TRIAL; CYSTIC FIBROSIS; DNA DRUG COMPLEX; DRUG DELIVERY SYSTEM; DRUG MIXTURE; DRUG SAFETY; EXPRESSION VECTOR; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; INHALATIONAL DRUG ADMINISTRATION; INTRANASAL DRUG ADMINISTRATION; INTRATRACHEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LUNG TOXICITY; NEBULIZATION; NONHUMAN; PRIORITY JOURNAL; RECOMBINANT PLASMID; REVIEW;

EID: 0343930665     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-409X(95)00100-L     Document Type: Review

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