Simulation of Single-Molecule Photocount Statistics in Microdroplets

Analytical Chemistry

Volumn 70, Issue 14, 1998, Pages 2964-2971

  Hill, Steven C ^a   Barnes, Michael D ^b   Lermer, Noah ^b   Whitten, William B ^b   Ramsey, J Michael ^b  

^a U S ARMY RESEARCH LABORATORY   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0005708762     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac971319d     Document Type: Article

References (46)

1. Barnes, M. D.; Whitten, W. B.; Ramsey, J. M. Anal. Chem. 1995, 67, 418A-423A.
2. Li, L.-Q.; Davis, L. M. Appl. Opt. 1995, 34, 3208-3217.
3. Soper, S. A.; Shera, E. B.; Martin, J. C.; Jett, J. H.; Hahn, J. H.; Nutter, H. L.; Keller, R. A. Anal. Chem. 1991, 63, 432-437.
4. Nie, S.; Chiu, D. T.; Zare, R. N. Anal. Chem. 1995, 67, 2849-2857.
5. Soper, S. A.; Mattingly, Q. L.; Vegunta, P. Anal. Chem. 1993, 65, 740-747.
6. Castro, A.; Shera, E. B. Appl. Opt. 1995, 34, 3218-3222.
7. Enderlein, J.; Robbins, D. L.; Ambrose, W. P.; Goodwin, P. M.; Keller, R. A. J. Phys. Chem. B 1997, 101, 3626-3632.
8. Keller, R. A.; Ambrose, W. P.; Goodwin, P. M.; Jett, J. H.; Martin, J. C.; Wu, M. Appl. Spectrosc. 1996, 50, A12-A32, and references therein.
9. Wilkerson, C. W.; Goodwin, P. M.; Ambrose, W. P.; Martin, J. C.; Keller, R. A. Appl. Phys. Lett. 1993, 62, 2030-2032.
10. Soper, S. A.; Nutter, H. L.; Keller, R. A.; Davis, L. M.; Shera, E. B. Photochem. Photobiol. 1993, 57, 972-977.
11. Nie, S.; Chiu, D. T.; Zare, R. N. Science 1994, 266, 1018-1021.
12. Chiu, D. T.; Zare, R. N. J. Am. Chem. Soc. 1996, 118, 6512-6513.
13. Ambrose, W. P.; Goodwin, P. M.; Enderlein, J.; Semin, D. J.; Martin, J. C.; Keller, R. A. Chem. Phys. Lett. 1997, 269, 365-370.
14. Moerner, W. E. Science 1994, 265, 46-53, and references therein.
15. Dickson, R. M.; Norris, D. J.; Tzeng, Y.-L.; Moerner, W. E. Science 1996, 274, 966-969.
16. Eigen, M.; Rigler, R. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 5740-5747; Rigler, R. J. Biotechnol. 1995, 41, 177-186.
17. Eigen, M.; Rigler, R. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 5740-5747; Rigler, R. J. Biotechnol. 1995, 41, 177-186.
18. Chen, D.-Y.; Dovichi, N. J. Anal. Chem. 1996, 68, 690-696.
19. Mathies, R. A.; Peck, K.; Stryer, L. Anal. Chem. 1990, 62, 1786-1791.
20. Xu, X.; Yeung, E. S. Science 1997, 275, 1106.
21. Schmidt, Th.; Schultz, G. J.; Baumgartner, W.; Gruber, H. T.; Schindler, H. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 2926-2929.
22. Kung, C.-Y.; Barnes, M. D.; Lermer, N.; Whitten, W. B.; Ramsey, J. M. Anal. Chem. 1998, 658-661.
23. Whitten, W. B.; Ramsey, J. M. Anal. Chem. 1991, 63, 1027-1031.
24. Whitten, W. B.; Ramsey, J. M. Appl. Spectrosc. 1992, 46, 1587-1589.
25. Ng, K. C.; Whitten, W. B.; Arnold, S.; Ramsey, J. M. Anal. Chem. 1992, 64, 2914-2919.
26. Barnes, M. D.; Whitten, W. B.; Ramsey, J. M. Anal. Chem. 1993, 65, 2360-2365.
27. Barnes, M. D.; Kung, C.-Y.; Whitten, W. B.; Ramsey, J. M.; Arnold, S. In Optical Processes in Microcavities; Chang, R. K., Campillo, A. J., Eds.; World Scientific: Singapore, 1996; 135-165.
28. Chew, H.; McNulty, P. J.; Kerker, M. Phys. Rev. A. 1976, 13, 396-404.
29. Hill, S. C.; Saleheen, H. I.; Barnes, M. D.; Whitten, W. B.; Ramsey, J. M. Appl. Opt. 1996, 35, 6278-6288.
30. Hill, S. C.; Barnes, M. D.; Whitten, W. B.; Ramsey, J. M. Appl. Opt. 1997, 36, 4425-4437.
31. Lock, J. A.; Hovenac, E. A. J. Opt. Soc. Am. A 1991, 8, 1541-1549.
32. Chowdhury, D. Q.; Barber, P. W.; Hill, S. C. Appl. Opt. 1992, 31, 3518-3523.
33. Basche, T. H.; Moerner, W. E.; Orrit, M.; Talon, H. Phys. Rev. Lett. 1992, 61, 1516.
34. Lermer, N.; Barnes, M. D.; Kung, C.-Y.; Whitten, W. B.; Ramsey, J. M. Anal. Chem. 1997, 69, 2115-2121.
35. Barnes, M. D.; Lermer, N.; Kung, C.-Y.; Whitten, W. B.; Ramsey, J. M.; Hill, S. C. Opt. Lett. 1997, 22, 1265-1267.
36. Chew, H. J. Chem. Phys. 1987, 87, 1355-1360.
37. Barnes, M. D.; Lermer, N.; Kung, C.-Y.; Whitten, W. B.; Ramsey, J. M.; Hill, S. C. Opt. Lett., in press.
38. Arnold, S.; Folan, L. M.; Korn, A. J. Appl. Phys. 1993, 74, 4291-4297.
39. The F(r) used here differs from that of refs 28 and 29 only in that the normalization is by the total fluorescence power from a dipole at r inside the sphere instead of by the fluorescence collected from a dipole in a homogeneous medium. For this paper the difference is more conceptual than practical. Note also that eq 3 assumes that the integration over dipole orientation can be brought inside the integral over frequency; although this is a reasonable approximation for the droplet sizes and lens numerical apertures used here (and essential for computational efficiency), it may not be adequate for smaller NA collection optics.
40. Moore, W. J. Physical Chemistry, 3rd ed.; Prentice-Hall: Englewood Cliffs, NJ, 1962; pp 234 and 343.
41. Press, W. H.; Teukolsky, S. A.; Vetterling, W. T.; Flannery, B. P. Numerical Recipes in Fortran, The Art of Scientific Computing, 2nd ed.; Cambridge: Cambridge, 1992. Uniform deviates for random positions, directions, etc., are obtained using ran2 (pp 277-280). Exponential, Gaussian, and Poisson deviates are obtained using expdev (p 278), gasdev (pp 279-280), and poidev (pp 283-285), respectively, along with ran2.
42. Fuchs, N. A. The Mechanics of Aerosols; Pergamon: Oxford, 1964; p. 245. See also: Tanford, C. Physical Chemistry of Macromolecules; Wiley: New York, 1963; pp 432-437, and compare that analysis with Moore (39).
43. Fuchs, N. A. The Mechanics of Aerosols; Pergamon: Oxford, 1964; p. 245. See also: Tanford, C. Physical Chemistry of Macromolecules; Wiley: New York, 1963; pp 432-437, and compare that analysis with Moore (39).
44. Lawrie, J. W. Glycerol and the Glycols; Chemical Catalogue Co.: New York, 1928; pp 204-205.
45. Snavely, B. B. In Dye Lasers; Schafer, F. P., Ed.; Springer-Verlag: New York, 1990; pp 93-95.
46. Barnes, M. D.; Whitten, W. B.; Ramsey, J. M. J. Opt. Soc. Am. B 1994, 1297-1304.