메뉴 건너뛰기




Volumn 83, Issue 12, 1998, Pages 4207-4211

Adrenocorticotropin and cortisol hyperresponsiveness to hexarelin in patients with Cushing's disease bearing a pituitary microadenoma, but not in those with macroadenoma

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CORTICOTROPIN; DEXAMETHASONE; GROWTH HORMONE RECEPTOR; HEXARELIN; HYDROCORTISONE; NALOXONE; VASOPRESSIN;

EID: 0005557586     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.12.4207     Document Type: Article
Times cited : (31)

References (36)
  • 3
    • 9844230970 scopus 로고    scopus 로고
    • Peptidomimetic regulation of growth hormone secretion
    • 3. Smith RG, Van der Ploeg LXT, Howard AD, et al. 1997 Peptidomimetic regulation of growth hormone secretion. Endocr Rev. 18:621-645.
    • (1997) Endocr Rev , vol.18 , pp. 621-645
    • Smith, R.G.1    Van Der Ploeg, L.X.T.2    Howard, A.D.3
  • 5
    • 0028903627 scopus 로고
    • Growth hormone-releasing peptide and its analogues. Novel stimuli to growth hormone release
    • 5. Korbonits M, Grossman AB. 1995 Growth hormone-releasing peptide and its analogues. Novel stimuli to growth hormone release. Trends Endocrinol Metab. 6:43-49.
    • (1995) Trends Endocrinol Metab , vol.6 , pp. 43-49
    • Korbonits, M.1    Grossman, A.B.2
  • 6
    • 0024396484 scopus 로고
    • Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites
    • 6. Codd EE, Shu AYL, Walker RF. 1989 Binding of a growth hormone releasing hexapeptide to specific hypothalamic and pituitary binding sites. Neuropharmacology. 28:1139-1144.
    • (1989) Neuropharmacology , vol.28 , pp. 1139-1144
    • Codd, E.E.1    Shu, A.Y.L.2    Walker, R.F.3
  • 8
    • 85011457887 scopus 로고    scopus 로고
    • 125I]p-benzoyl-phenylalanine hexarelin derivative
    • 125I]p-benzoyl-phenylalanine Hexarelin derivative. Endocrinology. 139:432-435.
    • (1998) Endocrinology , vol.139 , pp. 432-435
    • Ong, H.1    McNicoll, N.2    Escher, E.3
  • 9
    • 17644439585 scopus 로고    scopus 로고
    • Specific receptors for synthetic GH secretagogues in the human brain and pituitary gland
    • 9. Muccioli G, Ghè C, Ghigo MC, et al. 1998 Specific receptors for synthetic GH secretagogues in the human brain and pituitary gland. J Endocrínol. 157:99-106.
    • (1998) J Endocrinol , vol.157 , pp. 99-106
    • Muccioli, G.1    Ghè, C.2    Ghigo, M.C.3
  • 10
    • 9444246501 scopus 로고    scopus 로고
    • A receptor in pituitary and hypothalamus that functions in growth hormone release
    • 10. Howard AD, Feighner SD, Cully DF, et al. 1996 A receptor in pituitary and hypothalamus that functions in growth hormone release. Science. 273:974-977.
    • (1996) Science , vol.273 , pp. 974-977
    • Howard, A.D.1    Feighner, S.D.2    Cully, D.F.3
  • 11
    • 0030771596 scopus 로고    scopus 로고
    • Hexarelin, a synthetic growth-hormone releasing peptide, shows no interaction with corticotropin-releasing hormone and vasopressin on adrenocorticotropin and cortisol secretion in humans
    • 11. Arvat E, Maccagno B, Ramunni J, et al. 1997 Hexarelin, a synthetic growth-hormone releasing peptide, shows no interaction with corticotropin-releasing hormone and vasopressin on adrenocorticotropin and cortisol secretion in humans. Neuroendocrinology. 66:432-438.
    • (1997) Neuroendocrinology , vol.66 , pp. 432-438
    • Arvat, E.1    Maccagno, B.2    Ramunni, J.3
  • 12
    • 0029097574 scopus 로고
    • The effect of an opiate antagonist on the hormonal changes induced by hexarelin
    • 12. Korbonits M, Trainer PJ, Besser GM. 1995 The effect of an opiate antagonist on the hormonal changes induced by hexarelin. Clin Endocrinol (Oxf). 43:365-371.
    • (1995) Clin Endocrinol (Oxf) , vol.43 , pp. 365-371
    • Korbonits, M.1    Trainer, P.J.2    Besser, G.M.3
  • 13
    • 0030743911 scopus 로고    scopus 로고
    • Adrenocorticotropin-and cortisol-releasing effect of hexarelin, a synthetic growth hormone-releasing peptide, in normal subjects and patients with Cushing's syndrome
    • 13. Ghigo E, Arvat E, Ramunni J, et al. 1997 Adrenocorticotropin-and cortisol-releasing effect of hexarelin, a synthetic growth hormone-releasing peptide, in normal subjects and patients with Cushing's syndrome. J Clin Endocrinol Metab. 82:2439-2444.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2439-2444
    • Ghigo, E.1    Arvat, E.2    Ramunni, J.3
  • 14
    • 0030852329 scopus 로고    scopus 로고
    • Effects of GHRP-2 and hexarelin, two synthetic GH-releasing peptides, on GH, PRL, ACTH and cortisol level in man. Comparison with the effects of GHRH, TRH and hCRH
    • 14. Arvat E, Di Vito L, Maccagno B, et al. 1997 Effects of GHRP-2 and Hexarelin, two synthetic GH-releasing peptides, on GH, PRL, ACTH and cortisol level in man. Comparison with the effects of GHRH, TRH and hCRH. Peptides. 18:885-891.
    • (1997) Peptides , vol.18 , pp. 885-891
    • Arvat, E.1    Di Vito, L.2    Maccagno, B.3
  • 15
    • 9044228028 scopus 로고    scopus 로고
    • Mediation by the central nervous system is critical to the in vivo activity of the GH secretagogue L-692,585
    • 15. Hickey GJ, Drisko J, Faidley T, et al. 1996 Mediation by the central nervous system is critical to the in vivo activity of the GH secretagogue L-692,585. J Endocrinol. 148:371-380.
    • (1996) J Endocrinol , vol.148 , pp. 371-380
    • Hickey, G.J.1    Drisko, J.2    Faidley, T.3
  • 16
    • 0027248530 scopus 로고
    • A non-peptidyl growth hormone secretagogue
    • 16. Smith RG, Cheng K, Pong SS, et al. 1993 A non-peptidyl growth hormone secretagogue. Science. 260:1640-1643.
    • (1993) Science , vol.260 , pp. 1640-1643
    • Smith, R.G.1    Cheng, K.2    Pong, S.S.3
  • 17
    • 0028868979 scopus 로고
    • In vitro characterization of four novel classes of growth hormone-releasing peptide
    • 17. Elias KA, Ingle GS, Burnier JP, et al. 1995 In vitro characterization of four novel classes of growth hormone-releasing peptide. Endocrinology. 136:5694-5699.
    • (1995) Endocrinology , vol.136 , pp. 5694-5699
    • Elias, K.A.1    Ingle, G.S.2    Burnier, J.P.3
  • 18
    • 0031439845 scopus 로고    scopus 로고
    • Widespread transcription of the growth hormone-releasing peptide receptor gene in neuroendocrine human tumors
    • 18. De Keyzer Y, Lenne F, Bertagna X. 1997 Widespread transcription of the growth hormone-releasing peptide receptor gene in neuroendocrine human tumors. Eur J Endocrinol. 137:715-718.
    • (1997) Eur J Endocrinol , vol.137 , pp. 715-718
    • De Keyzer, Y.1    Lenne, F.2    Bertagna, X.3
  • 19
    • 0030909925 scopus 로고    scopus 로고
    • Activation of the hypothalamo-pituitary-adrenal axis by the growth hormone (GH) secretagogue, GH-releasing peptide-6, in rats
    • 19. Thomas GB, Fairhall KM, Robinson ICAF. 1997 Activation of the hypothalamo-pituitary-adrenal axis by the growth hormone (GH) secretagogue, GH-releasing peptide-6, in rats. Endocrinology. 138:1585-1591.
    • (1997) Endocrinology , vol.138 , pp. 1585-1591
    • Thomas, G.B.1    Fairhall, K.M.2    Robinson, I.C.A.F.3
  • 20
    • 0031961561 scopus 로고    scopus 로고
    • Effects of dexamethasone and alprazolam, a benzodiazepine, on the stimulatory effect of hexarelin, a synthetic GHRP, on ACTH, cortisol and GH secretion in humans
    • 20. Arvat E, Maccagno B, Ramunni J, et al. 1998 Effects of dexamethasone and alprazolam, a benzodiazepine, on the stimulatory effect of hexarelin, a synthetic GHRP, on ACTH, cortisol and GH secretion in humans. Neuroendocrinology. 67:310-316.
    • (1998) Neuroendocrinology , vol.67 , pp. 310-316
    • Arvat, E.1    Maccagno, B.2    Ramunni, J.3
  • 21
    • 0026693320 scopus 로고
    • Corticotropin-releasing hormone in humans
    • 21. Orth DN. 1992 Corticotropin-releasing hormone in humans. Endocr Rev. 13:164-191.
    • (1992) Endocr Rev , vol.13 , pp. 164-191
    • Orth, D.N.1
  • 22
    • 0031057817 scopus 로고    scopus 로고
    • Induction of c-fos messenger ribonucleic acid in neuropeptide Y and growth hormone (GH)-releasing factor neurones in the rat arcuate nucleus following systemic injection of the GH segretagogue, GH-releasing peptide-6
    • 22. Dickson SL, Luckman SM. 1997 Induction of c-fos messenger ribonucleic acid in neuropeptide Y and growth hormone (GH)-releasing factor neurones in the rat arcuate nucleus following systemic injection of the GH segretagogue, GH-releasing peptide-6. Endocrinology. 138:771-777.
    • (1997) Endocrinology , vol.138 , pp. 771-777
    • Dickson, S.L.1    Luckman, S.M.2
  • 23
    • 0031936860 scopus 로고    scopus 로고
    • Acromegaly and Cushing's sindrome due to ectopic production of GHRH and ACTH by a thymic carcinoid tumour: In vitro responses to GHRH and GHRP-6
    • 23. Jansson JO, Svensson J, Bengtsson BA, et al. 1998 Acromegaly and Cushing's sindrome due to ectopic production of GHRH and ACTH by a thymic carcinoid tumour: in vitro responses to GHRH and GHRP-6. Clin Endocrinol (Oxf). 48:243-250.
    • (1998) Clin Endocrinol (Oxf) , vol.48 , pp. 243-250
    • Jansson, J.O.1    Svensson, J.2    Bengtsson, B.A.3
  • 24
    • 0031912713 scopus 로고    scopus 로고
    • Cushing's disease: A comparison of pituitary corticotroph microadenomas and macroadenomas
    • 24. Selvais P, Donckier J, Buysschaert M, Maiter D. 1998 Cushing's disease: a comparison of pituitary corticotroph microadenomas and macroadenomas. Eur J Endocrinol. 138:153-159.
    • (1998) Eur J Endocrinol , vol.138 , pp. 153-159
    • Selvais, P.1    Donckier, J.2    Buysschaert, M.3    Maiter, D.4
  • 25
    • 0030837358 scopus 로고    scopus 로고
    • Clinicopathological study of Cushing's disease with large pituitary adenoma
    • 25. Ikeda H, Yoshimoto T, Ogawa Y, Mizoi K, Murakami O. 1997 Clinicopathological study of Cushing's disease with large pituitary adenoma. Clin Endocrinol (Oxf). 46:669-679.
    • (1997) Clin Endocrinol (Oxf) , vol.46 , pp. 669-679
    • Ikeda, H.1    Yoshimoto, T.2    Ogawa, Y.3    Mizoi, K.4    Murakami, O.5
  • 26
    • 7844222086 scopus 로고    scopus 로고
    • Biochemical assesment of Cushing's disease in patients with corticotroph macroadenomas
    • 26. Katznelson L, Bogan JS, Trob JR, et al. 1998 Biochemical assesment of Cushing's disease in patients with corticotroph macroadenomas. J Clin Endocrinol Metab. 83:1619-1623.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1619-1623
    • Katznelson, L.1    Bogan, J.S.2    Trob, J.R.3
  • 27
    • 0030788223 scopus 로고    scopus 로고
    • Effect of desmopressin on ACTH and cortisol secretion in states of ACTH excess
    • 27. Colombo P, Passini E, Re T, Faglia G, Ambrosi B. 1997 Effect of desmopressin on ACTH and cortisol secretion in states of ACTH excess. Clin Endocrinol (Oxf). 46:661-668.
    • (1997) Clin Endocrinol (Oxf) , vol.46 , pp. 661-668
    • Colombo, P.1    Passini, E.2    Re, T.3    Faglia, G.4    Ambrosi, B.5
  • 28
    • 0030752999 scopus 로고    scopus 로고
    • Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome
    • 28. Cuneo RC, Lee W, Harper J, et al. 1997 Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome. Clin Endocrinol (Oxf). 46:607-618.
    • (1997) Clin Endocrinol (Oxf) , vol.46 , pp. 607-618
    • Cuneo, R.C.1    Lee, W.2    Harper, J.3
  • 29
    • 0027988189 scopus 로고
    • Inhibition of growth hormone release after the combined administration of GHRH and GHRP-6 in patients with Cushing's syndrome
    • 29. Leal Cerro A, Pumar A, Garcia-Garcia E, Dieguez C, Casanueva FF. 1994 Inhibition of growth hormone release after the combined administration of GHRH and GHRP-6 in patients with Cushing's syndrome. Clin Endocrinol (Oxf). 41:649-654.
    • (1994) Clin Endocrinol (Oxf) , vol.41 , pp. 649-654
    • Leal Cerro, A.1    Pumar, A.2    Garcia-Garcia, E.3    Dieguez, C.4    Casanueva, F.F.5
  • 30
    • 0028940628 scopus 로고
    • Effect of arginine and pyridostigmine on the GHRH-induced GH rise in obesity and Cushing's syndrome
    • 30. Procopio M, Invitti C, Maccarìo M, et al. 1995 Effect of arginine and pyridostigmine on the GHRH-induced GH rise in obesity and Cushing's syndrome. Int J Obes. 19:108-112.
    • (1995) Int J Obes , vol.19 , pp. 108-112
    • Procopio, M.1    Invitti, C.2    Maccarìo, M.3
  • 31
    • 84995856149 scopus 로고
    • Suppressed spontaneus and stimulated growth hormone secretion in Cushing's disease before and after surgical care
    • 31. Magiakou MA, Mastorakos G, Gomez MT, Rose SR, Chrousos GP. 1994 Suppressed spontaneus and stimulated growth hormone secretion in Cushing's disease before and after surgical care. J Clin Endocrinol Metab. 78:131-137.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 131-137
    • Magiakou, M.A.1    Mastorakos, G.2    Gomez, M.T.3    Rose, S.R.4    Chrousos, G.P.5
  • 32
    • 0029739705 scopus 로고    scopus 로고
    • Role of glucocorticoids in the neuroregulation of growth hormone secretion
    • 32. Dieguez C, Mallo F, Senaris R, et al. 1996 Role of glucocorticoids in the neuroregulation of growth hormone secretion. J Pediatr Endocrinol Metab. 9:255-260.
    • (1996) J Pediatr Endocrinol Metab , vol.9 , pp. 255-260
    • Dieguez, C.1    Mallo, F.2    Senaris, R.3
  • 33
    • 0029935185 scopus 로고    scopus 로고
    • Impaired growth hormone secretion in obese subjects is partially reversed by acipimox-mediated plasma free fatty acid depression
    • 33 Cordido F, Peino R, Penalva A, Alvarez CV, Casanueva FF, Dieguez C. 1996 Impaired growth hormone secretion in obese subjects is partially reversed by acipimox-mediated plasma free fatty acid depression. J Clin Endocrinol Metab. 81:914-918.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 914-918
    • Cordido, F.1    Peino, R.2    Penalva, A.3    Alvarez, C.V.4    Casanueva, F.F.5    Dieguez, C.6
  • 34
    • 0028966013 scopus 로고
    • Metabolic modulation of the growth-hormone-releasing activity of hexarelin in man
    • 34. Maccario M, Arvat E, Procopio M, et al. 1995 Metabolic modulation of the growth-hormone-releasing activity of hexarelin in man. Metabolism. 44:134-138.
    • (1995) Metabolism , vol.44 , pp. 134-138
    • Maccario, M.1    Arvat, E.2    Procopio, M.3
  • 35
    • 0028968462 scopus 로고
    • Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: Evidence that GHRP-6 main action is exerted at the hypothalamic level
    • 35. Popovic V, Damjanovic S, Micic D, Djurovic M, Dieguez C, Casanueva FF. 1995 Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: evidence that GHRP-6 main action is exerted at the hypothalamic level. J Clin Endocrinol Metab. 80:942-947.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 942-947
    • Popovic, V.1    Damjanovic, S.2    Micic, D.3    Djurovic, M.4    Dieguez, C.5    Casanueva, F.F.6
  • 36
    • 0028807113 scopus 로고
    • Absence of growth hormone (GH) secretion after the administration of either GH releasing hormone (GHRH), GH-releasing peptide (GHRP-6), or GHRH plus GHRP-6 in children with neonatal pituitary stalk transection
    • 36. Pombo M, Barreiro J, Penalva A, Peino R, Dieguez C, Casanueva FF. 1995 Absence of growth hormone (GH) secretion after the administration of either GH releasing hormone (GHRH), GH-releasing peptide (GHRP-6), or GHRH plus GHRP-6 in children with neonatal pituitary stalk transection. J Clin Endocrinol Metab. 80:3180-3184.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3180-3184
    • Pombo, M.1    Barreiro, J.2    Penalva, A.3    Peino, R.4    Dieguez, C.5    Casanueva, F.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.