Comparison of Mycobacterium tuberculosis genomes reveals frequent deletions in a 20 kb variable region in clinical isolates

Yeast

Volumn 17, Issue 4, 2000, Pages 272-282

  Ho, Timothy B L ^a   Robertson, Brian D ^a   Michael Taylor, G ^a   Shaw, Roryj ^a   Young, Douglas B ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Gene deletions; Insertion sequences; Mycobactcria; Strain variation; Tuberculosis

Indexed keywords

EID: 0005188295     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0061(200012)17:4<272::aid-yea48>3.0.co;2-2     Document Type: Article

References (25)

1. Behr MA, Wilson MA, Gill WP, et al. 1999. Comparative genomics of BCG vaccines by whole-genome DNA microarray. Science 284: 1520-1523.
2. Brosch R, Gordon SV, Eiglmeier K, el al. 2000. Genomics, biology, and evolution of the Mycobacterhun tuberculosis complex. In Molecular Genetics of Mycobacleria, Hatfull GF, Jacobs WRJ (eds). ASM Press: Washington, DC; 19-36.
3. Brosch R, Philipp WJ, Stavropoulos E, Colston MJ, Cole ST, Gordon SV. 1999. Genomic analysis reveals variation between Pifycobacterium tuberculosis H37Rv and the attenuated M. tuberculosis H37Ra strain. Infect Immun 67: 5768-5774.
4. Chaves F, Yang Z, el Hajj H, et al 1996. Usefulness of the secondary probe pTBN12 in DNA fingerprinting of Mycobacterhun tuberculosis. J Clin Microbiol 34: 1118-1123.
5. Cole ST, Brosch R, Parkhill J, et al. 1998. Deciphering the biology of Mycobactcrium tuberculosis from the complete genome sequence. Nature 393: 537-544.
6. Dye C, Scheele S, Dolin P, Pathania V, Raviglione MC. 1999. Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project. J Am Mcd Assoc 282: 677-686.
7. Fang Z, Doig C, Kenna DT, et al. 1999. IS6110-mediated deletions of wild-type chromosomes of Mycobacterium tuberculosis. J Bacterial 181: 1014-1020.
8. Fang Z, Forbes KJ. 1997. A Mycobacterium tuberculosis IS611O preferential locus (ipl) for insertion into the genome. J Clin Microbiol 35: 479-481.
9. Fomukong N, Beggs M, el Hajj H, Templeton G, Eisenach K, Cave MD. 1997. Differences in the prevalence of IS6110 insertion sites in Mycobacterium tuberculosis strains: low and high copy number of IS67110. Tubcrc Lung Dis 78: 109-116.
10. Gordon SV, Brosch R, Billault A, Garnier T, Eiglmeier K, Cole ST. 1999. Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays. Mol Microbiol 32: 643-655.
11. Goyal M, Saunders NA, van Embden JD, Young DB, Shaw RJ. 1997. Differentiation of Mycobacteriwn tuberculosis isolates by spoligotyping and IS6I10 restriction fragment length polymorphism. J Clin Microbiol 35: 647-651.
12. Kamerbeek J, Schouls L, Kolk A, et al. 1997. Simultaneous detection and strain differentiation of Mycobacteriwn tuberculosis for diagnosis and epidemiology. J Clin Microbiol 35: 907-914.
13. Kurepina NE, Sreevatsan S, Plikaytis BB, et al. 1998. Characterization of the phylogenetic distribution and chromosomal insertion sites of five IS61170 elements in Mycobacteriwn tuberculosis', non-random integration in the dnaA-dnaN region. Tuberc Lung Dis 79: 31-42.
14. Mitchison DA, Selkon JB, Lloyd J. 1963. Virulence in the guinea pig, susceptibility to hydrogen peroxide, and the catalase activity of isoniazid-sensitive tubercle bacilli from South Indian and British patients. J Palhol Bacterial 86: 377-386.
15. Ordway DJ, Sonnenberg MO, Donahue SA, Belisle JT, Orme IM. 1995. Drug-resistant strains of Mycobactcrium tuberculosis exhibit a range of virulence for mice. Infect Immun 63: 741-743.
16. Rhee JT, Piatek AS, Small PM, et al. 1999. Molecular epidemiologic evaluation of transmissibility and virulence of Mycobactcrium tuberculosis. J Clin Microbiol 37: 1764-1770.
17. Sampson SL, Warren RM, Richardson M, van der Spuy GD, van Helden PD. 1999. Disruption of coding regions by IS6110 insertion in Mycobacteriwn tuberculosis. Tuberc Lung Dis 79: 349-359.
18. Schafer W. 1993. The role of cutinase in fungal pathogenicity. Trends Microbiol I: 69-71.
19. Small PM, Hopewell PC, Singh SP, et al. 1994. The epidemiology of tuberculosis in San Francisco. A population-based study using conventional and molecular methods. N EnglJ A fed 330: 1703-1709.
20. Sreevatsan S, Pan X, Stockbauer KE, et al. 1997. Restricted structural gene polymorphism in the Mycobactcrium tuberculosis complex indicates evolutionarily recent global dissemination. Proc Natl Acad Sei USA 94: 9869-9874.
21. Titball RW. 1993. Bacterial phospholipases C. Microbiol Rev 57: 347-366.
22. Vahvay SE, Sanchez MP, Shinnick TF, et al. 1998. An outbreak involving extensive transmission of a virulent strain of Mycobacteriwn tuberculosis. N Engl J Mcd 338: 633-639.
23. van Embden JD, Cave MD, Crawford JT, et al. 1993. Strain identification of Mycobacteriwn tuberculosis by DNA fingerprinting: recommendations for a standardized methodology. J Clin Microbiol 31: 406-409.
24. Vera-Cabrera L, Howard ST, Laszlo A, Johnson WM. 1997. Analysis of genetic polymorphism in the phospholipase region of Mycobacteriwn tuberculosis. J Clin Microbiol 35: 1190-1195.
25. Zhang Y, Mazurek GH, Cave MD, et al. 1992. DNA polymorphisms in strains of Mycobacteriwn tuberculosis analyzed by pulsed-field gel electrophoresis: a tool for epidemiology. J Clin Microbiol 30: 1551-1556.