A general mathematical modelling technique for bioprocesses in engineering applications

Systems Analysis Modelling Simulation

Volumn 35, Issue , 1999, Pages 87-113

  Bogaerts, Philippe ^a   Castillo, Jose ^a   Hanus, Raymond ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Bioprocesses; Identification; Mathematical modelling; Simulation

Indexed keywords

MODEL STRUCTURES;

BACTERIAL CULTURES; ENGINEERING APPLICATIONS; KINETIC MODELING; MACROSCOPIC LEVELS; MODEL PARAMETERS; REACTION SCHEMES; SIMULATION EXAMPLE; SPECIFIC GROWTH RATE;

REACTION KINETICS;

EID: 0004512719     PISSN: 02329298     EISSN: 10294902     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Tziampazis, E. and Sambanis, A. (1994). Modelling of cell culture processes, Cytotechnology, 14, 191-204.
2. Bailey, J. E. and Ollis, D. F. (1986). Biochemical Engineering Fundamentals, McGraw-Hill Chemical Engineering Series, 2nd edition.
3. Romero, G., Flaus, J. M. and Cheruy, A. (1997). Semiqualitative Modelling of Bioprocesses, Mathematical Modelling of Systems, 3(3), 246-264.
4. Corrieu, G., Latrille, E., Picque, D. and Perret, B. (1994). Recent developments of indirect measurements and software sensors for bioprocess control, Aut. Control of Food and Biolog. Processes (Devel. in Food Science), 36, 27-34, Elsevier.
5. Montague, G. and Morris, J. (1994). Neural network contributions in biotechnology, Tibtech August 1994, 12, 312.
6. Thibault, J., Van Breusegem, V. and Cheruy, A. (1990). On-line prediction of fermentation variables using neural networks, Biotechnology and Bioengineering, 36, 1041-1048.
7. Yager, R. R. and Filev, D. P. (1994). Essentials of Fuzzy Modeling and Control, J. Wiley & Sons.
8. Bastin, G. and Van Impe, J. F. (1995). Nonlinear and adaptive control in biotechnology: A tutorial, European Journal of Control, 1, 37-53.
9. Ryckaert, V. G. and Van Impe, J. F. (1996). Design methodologies for nonlinear observers - Application to biological models. Proceedings of the CESA '96 IMACS Mutticonference, Symposium on Modelling, Analysis and Simulation, 2, 1052-1057, Lille (France).
10. Chotteau, V. (1995). A general modelling methodology for animal cell cultures, Ph.D. Thesis, Universite Catholique de Louvain (Belgium).
11. Barford, J. P., Phillips, P. J. and Harbour, C. (1992). Simulation of animal cell metabolism, Cytotechnology, 10, 63-74.
12. Bonarius, H. P. J., Hatzimanikatis, V., Meesters, K. P. H., de Gooijer, C. D., Schmid, G. and Tramper, J. (1996). Metabolic Flux Analysis of Hybridoma Cells in Different Culture Media Using Mass Balances, Biotechnology and Bioengineering, 50, 299-318.
13. Xie, L. and Wang, D. I. C. (1996). Material Balance Studies on Animal Cell Metabolism Using a Stoichiometrically Based Reaction Network, Biotechnology and Bioengineering, 52, 579-590.
14. Bastin, G. and Dochain, D. (1990). Online Estimation and Adaptive Control of Bioreactors, Elsevier.
15. Goergen, J. L., Marc, A. and Engasser, J. M. (1994). Biochemistry of cells in culture: modelling, In: "Cell and Tissue Culture: Laboratory Procedures Dovle, A., Griffiths, J. B. and Newell, D. G. (Eds.), John Wiley and Sons, 8B, 2.1-2.19, Chichester.
16. Bajpai, R. K. and Reuß, M. (1980). A Mechanistic Model for Penicillin Production, J. Chem. Tech. Bioteclmol., 30, 332-344.
17. Van Impe, J. F. and Bastin, G. (1995). Optimal adaptive control of fed-batch fermentation processes. Control Eng. Practice, 3, 939-954.
18. Chen, L. and Bastin, G. (1996). Structural Identifiability of the Yield Coefficients in Bioprocess Models When the Reaction Rates Are Unknown, Mathematical Biosciences, 132, 35-67.
19. Holmberg, A. (1983). On the accuracy of estimating the parameters of models containing Michaelis-Menten type nonlinearities. In: "Modelling and Data Analysis in Biotechnology and Medical Engineering", Vansteenkiste, G. C. and Young, P. C. (Eds.), North-Holland, Amsterdam, p. 202.