Neuroimaging in OCD: Clinical Implications

CNS Spectrums

Volumn 3, Issue S1, 1998, Pages 26-29

  Rauch, Scott L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0003849646     PISSN: 10928529     EISSN: 21656509     Source Type: Journal    
DOI: 10.1017/S1092852900007185     Document Type: Article

References (41)

1. Rauch, SL, Renshaw, PF. Clinical neuroimaging in psychiatry. Harvard Rev Psychiatry. 1995; 2: 297–312.
2. Baxter, LR, Schwartz, JM, Guze, BH, et al. Neuroimaging in obsessive-compulsive disorder: seeking the mediating neuroanatomy. In: Jenike, MA, Baer, L, Minichiello, WE, eds. Obsessive Compulsive Disorder: Theory and Management. 2nd ed. Chicago: Year Book Medical Publishers; 1990: 167–188.
3. Rauch, SL, Jenike, MA. Neural mechanisms of obsessive-compulsive disorder. Curr Rev Mood Anxiety Disord. 1997; 1: 84–94.
4. Behar, K, Rapoport, JL, Berg, CJ, et al. Computerized tomography and neuropsychological test measures in adolescents with obsessive-compulsive disorder. Am J Psychiatry. 1984; 141: 363–368.
5. Insel, TR, Donnely, EF, Lalakea, ML, et al. Neurological and neuropsychological studies of patients with obsessive-compulsive disorder. Biol Psychiatry. 1983; 18: 741–751.
6. Kellner, CH, Jolley, RR, Holgate, RC, et al. Brain MRI in obsessive-compulsive disorder. Psychiatry Res. 1991; 36: 45–49.
7. Luxenberg, JS, Swedo, SE, Flament, MF, et al. Neuroanatomical abnormalities in obsessive-compulsive disorder detected with quantitative X-ray computed tomography. Am J Psychiatry. 1988; 145: 1089–1093.
8. Aylward, EH, Harris, GJ, Hoehn-Saric, R, et al. Normal caudate nucleus in obsessive-compulsive disorder assessed by quantitative neuroimaging. Arch Gen Psychiatry. 1996; 53: 577–584.
9. Jenike, MA, Breiter, HC, Baer, L, et al. Cerebral structural abnormalities in obsessive-compulsive disorder: a quantitative morphometric magnetic resonance imaging study. Arch Gen Psychiatry. 1996; 53: 625–632.
10. Robinson, D, Wu, H, Munne, RA, et al. Reduced caudate nucleus volume in obsessive-compulsive disorder. Arch Gen Psychiatry. 1995; 52: 393–398.
11. Scarone, S, Colombo, C, Livian, S, et al: Increased right caudate nucleus size in obsessive compulsive disorder: detection with magnetic resonance imaging. Psychiatry Res Neuroimaging. 1992; 45: 115–121.
12. O'Sullivan, R, Rauch, SL, Breiter, HC, et al. Reduced basal ganglia volumes in trichotillomania by morphometric MRI. Biol Psychiatry. 1997; 42: 39–45.
13. Peterson, B, Riddle, MA, Cohen, DJ, et al. Reduced basal ganglia volumes in Tourette's syndrome using threedimensional reconstruction techniques from magnetic resonance images. Neurology. 1993; 43: 941–949.
14. Singer, HS, Reiss, AL, Brown, JE, et al. Volumetric MRI changes in basal ganglia of children with Tourette's syndrome. Neurology. 1993; 43: 950–956.
15. Rosenberg, DR, Keshavan, MS, O'Hearn, KM, et al. Frontostriatal measurement in treatment-naive children with obsessive-compulsive disorder. Arch Gen Psychiatry. 1997; 54: 824–830.
16. Hyde, TM, Stacey, ME, Coppola, R, et al. Cerebral morphometric abnormalities in Tourette's syndrome: a quantitative MRI study of monozygotic twins. Neurology. 1995; 45: 1176–1182.
17. Hoehn-Saric, R, Benkelfat, C. Structural and functional brain imaging in obsessive compulsive disorder. In: Hollander, E, Zohar, J, Marazziti, D, et al, eds. Current Insights in Obsessive Compulsive Disorder. New York: John Wiley; 1994: 183–214.
18. Baxter, LR Jr, Schwartz, JM, Bergman, KS, et al. Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder. Arch Gen Psychiatry. 1992; 49: 681–689.
19. Benkelfat, C, Nordahl, TE, Semple, WE, et al. Local cerebral glucose metabolic rates in obsessive-compulsive disorder: patients treated with clomipramine. Arch Gen Psychiatry. 1990; 47: 840–848.
20. Perani, D, Colombo, C, Bressi, S, et al. FDG PET study in obsessive-compulsive disorder: a clinical metabolic correlation study after treatment. Br J Psychiatry. 1995; 166: 244–250.
21. Schwartz, JM, Stoessel, PW, Baxter, LR, et al. Systematic changes in cerebral glucose metabolic rate after successful behavior modification. Arch Gen Psychiatry. 1996; 53: 109–113.
22. Swedo, SE, Pietrini, P, Leonard, HL, et al. Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder: revisualization during pharmacotherapy. Arch Gen Psychiatry. 1992; 49: 690–694.
23. Breiter, HC, Rauch, SL, Kwong, KK, et al. Functional magnetic resonance imaging of symptom provocation in obsessive compulsive disorder. Arch Gen Psychiatry. 1996; 53: 595–606.
24. McGuire, PK, Bench, CJ, Frith, CD, et al. Functional anatomy of obsessive-compulsive phenomena. Br J Psychiatry. 1994; 164: 459–468.
25. 2 and positron emission tomography. Arch Gen Psychiatry. 1994; 51: 62–70.
26. Zohar, J, Insel, T, Berman, K, et al. Anxiety and cerebral blood flow during behavioral challenge: dissociation of central from peripheral and subjective measures. Arch Gen Psychiatry. 1989; 46: 505–510.
27. Rauch, SL, Savage, CR, Alpert, NM, et al. A positron emission tomographic study of simple phobic symptom provocation. Arch Gen Psychiatry. 1995; 52: 20–28.
28. Rauch, SL, van der Kolk, BA, Fisler, RE, et al: A symptom provocation study of posttraumatic stress disorder using positron emission tomography and script-driven imagery. Arch Gen Psychiatry. 1997; 53: 380–387.
29. Benkelfat, C, Bradwejn, J, Meyer, E, et al. Functional neuroanatomy of CCK4-induced anxiety in normal healthy volunteers. Am J Psychiatry. 1995; 152: 1180–1184.
30. Rauch, SL, Savage, CR, Brown, HD, et al: A PET investigation of implicit and explicit sequence learning. Hum Brain Mapping. 1995; 3: 271–286.
31. Rauch, SL, Whalen, PJ, Savage, CR, et al. Striatal recruitment during an implicit sequence learning task as measured by functional magnetic resonance imaging. Hum Brain Mapping. 1997; 5: 124–132.
32. Rauch, SL, Savage, CR, Alpert, NM, et al. Probing striatal function in obsessive compulsive disorder: a PET study of implicit sequence learning. J Neuropsychiatry. 1997; 9: 568–573.
33. Rauch, SL, Whalen, PJ, Curran, T, et al. Thalamic deactivation during early implicit sequence learning: a functional MRI study. NeuroReport. 1998; 9: 865–870.
34. Whalen, PJ, Bush, G, McNally, R, et al. The Digital Emotional Stroop activates anterior cingulate cortex: an fMRI study. Neuroimage. 1997; 5: S121. Abstract.
35. Whalen, PJ, Rauch, SL, Etcoff, NL, et al. Masked presentations of emotional facial expressions modulate amygdala activity without explicit knowledge. J Neurosci. 1998; 18: 411–418.
36. Rauch, SL, Dougherty, DD, Shin, LM, et al. Neural correlates of factor-analyzed OCD symptom dimensions: a PET stucy. CNS Spectrums. In press.
37. Grachev, ID, Brieter, HC, Rauch, SL, et al. Structural abnormalities of frontal neocortex in obsessive-compulsive disorder. Arch Gen Psychiatry. 1998; 55: 181–182.
38. Ebert, D, Speck, O, Konig, A, et al. 1H magnetic resonance spectroscopy in obsessive compulsive disorder: evidence for neuronal loss in the cingulate gyrus and right striatum. Psychiatric Res: Neuroimaging. 1997; 74: 173–176.
39. Hollander, E, Prohovnik, I, Stein, DJ. Effects of m-CPP induced obsessions on cortical blood flow. J Neuropsychiatry. 1995; 7: 485–490.
40. George, MS, ed. Transcranial magnetic stimulation: mapping and modifying brain-behavior relationships. CNS Spectrums. 1997; 2.
41. Dager, SR, Steen, RG. Applications of magnetic resonance spectroscopy to the investigation of neuropsychiatric disorders. Neuropsychopharmacology. 1992; 6: 249–266.