메뉴 건너뛰기




Volumn 4, Issue SUPPL. 1, 1999, Pages 2-13

The pharmacological profile of dienogest

Author keywords

Antiandrogenic activity; Dienogest; Mode of action Antiproliferative activity; Pharmacokinetics; Toxicity

Indexed keywords


EID: 0003258758     PISSN: 13625187     EISSN: 14730782     Source Type: Journal    
DOI: 10.3109/13625189909085259     Document Type: Article
Times cited : (58)

References (27)
  • 1
    • 0025184340 scopus 로고
    • Mechanism based inactivation of human liver microsomal cytochrome P450 IIIA4 by gestodene
    • Guengerich FP. Mechanism based inactivation of human liver microsomal cytochrome P450 IIIA4 by gestodene. Chem Res Toxicol 1990; 3: 363-5
    • (1990) Chem Res Toxicol , vol.3 , pp. 363-365
    • Guengerich, F.P.1
  • 2
    • 0038812328 scopus 로고
    • Der Einfluß von Dienogest auf das humane Cytochrom P-450 Enzymsystem in vitro
    • Teichmann AT ed. 2nd edn. Berlin: Walter de Gruyter
    • Böcker R, Kleingeist B. Der Einfluß von Dienogest auf das humane Cytochrom P-450 Enzymsystem in vitro. In Teichmann AT, ed. Dienogest - Präklinik und Klitiik cities neuen Gestagens. 2nd edn. Berlin: Walter de Gruyter, 1995: 141-7
    • (1995) Dienogest - Präklinik und Klitiik Cities Neuen Gestagens , pp. 141-147
    • Böcker, R.1    Kleingeist, B.2
  • 10
    • 0344414990 scopus 로고
    • Prüfung der initiierenden Wirksamkeit von Dienogest und Chlormadinonacetat im 'Rat Liver Foci Bioassay'
    • Teichmann AT, ed. 2nd edn. Berlin: Walter de Gruyter
    • Oesterle D, Demi E. Prüfung der initiierenden Wirksamkeit von Dienogest und Chlormadinonacetat im 'Rat Liver Foci Bioassay'. In Teichmann AT, ed. Dienogest - Praklinik und Klinik eines neuen Gestagens. 2nd edn. Berlin: Walter de Gruyter, 1995: 73-8
    • (1995) Dienogest - Praklinik und Klinik Eines Neuen Gestagens , pp. 73-78
    • Oesterle, D.1    Demi, E.2
  • 11
    • 0018973348 scopus 로고
    • Effect of STS 557 on semen composition, fertility and sexual behaviour of male rabbits
    • DOI 10.1016/0010-7824(80)90036-0
    • Freund H, Hesse G, Oettel M. Effect of STS 557 on semen composition, fertility and sexual behavior of male rabbits. Contraception 1980; 21: 641-50 (Pubitemid 10046291)
    • (1980) Contraception , vol.21 , Issue.6 , pp. 641-650
    • Freund, H.1    Hesse, G.2    Oettel, M.3
  • 12
    • 0025364516 scopus 로고
    • Contraceptive potentiality of STS-557 - A feasibility study in male bonnet monkey (Macaca radiata)
    • Majumdar SS, Chaudhary J, Sharma RK, Das RP. Contraceptive potentiality of STS 557 - a feasibility study in male bonnet monkey (Macaca radiata). Contraception 1990; 41: 641-53 (Pubitemid 20195403)
    • (1990) Contraception , vol.41 , Issue.6 , pp. 641-653
    • Majumdar, S.S.1    Chaudhary, J.2    Sharma, R.K.3    Das, R.P.4
  • 13
    • 80052099725 scopus 로고    scopus 로고
    • Chronische Toxizitätsprufung der Substanz STS 557 am Beagle-Hund - Supplementary Report
    • Dettmann R, Kramp B. Chronische Toxizitätsprufung der Substanz STS 557 am Beagle-Hund - Supplementary Report. WPU Rostock 13.09.1979
    • WPU Rostock 13.09.1979
    • Dettmann, R.1    Kramp, B.2
  • 15
    • 0030273673 scopus 로고    scopus 로고
    • The novel progestin drospirenone and its natural counterpart progesterone: Biochemical profile and antiandrogenic potential
    • DOI 10.1016/S0010-7824(96)00195-3
    • Fuhrmann U, Krattenmacher R, Slater EP, Fritzemeier, KH. The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and antiandrogenic potential. Contraception 1996; 54: 243-51 (Pubitemid 26398621)
    • (1996) Contraception , vol.54 , Issue.4 , pp. 243-251
    • Fuhrmann, U.1    Krattenmacher, R.2    Slater, E.P.3    Fritzemeier, K.-H.4
  • 17
    • 80052093415 scopus 로고    scopus 로고
    • Determination of the novel progestin dienogest in different tissues
    • Presented at the, Seville, Spain, May
    • Kaufmann G, Hübler D, Oettel M. Determination of the novel progestin dienogest in different tissues. Presented at the IV European Congress of Endocrinology, Seville, Spain, May 1998, P3-286
    • (1998) IV European Congress of Endocrinology
    • Kaufmann, G.1    Hübler, D.2    Oettel, M.3
  • 18
    • 0022319170 scopus 로고
    • Effects of the new progestagen STS 557 on the biosynthesis of steroids in tissue slices of the human ovary
    • Schürenkamper P, Lisse K. Effects of the new progestagen STS 557 on the biosynthesis of steroids in tissue slices of the human ovary. Exp Clin Endocrinol 1985; 86: 185-9 (Pubitemid 17204397)
    • (1985) Experimental and Clinical Endocrinology , vol.86 , Issue.2 , pp. 185-189
    • Schurenkamper, P.1    Lisse, K.2
  • 19
    • 0002752278 scopus 로고
    • Die Wirkung von Dienogest auf die hypothalamischhypophysäre Achse: Ergebnisse einer Pilotstudie
    • Teichmann AT ed. 2nd edn. Berlin: Walter de Gruyter
    • Schleußner E, Michels W, Bethge S, Klinger C. Die Wirkung von Dienogest auf die hypothalamischhypophysäre Achse: Ergebnisse einer Pilotstudie. In Teichmann AT, ed. Dienogest - Präklinik und Klinik eines neuen Gestagens. 2nd edn. Berlin: Walter de Gruyter, 1995: 171-9
    • (1995) Dienogest - Präklinik und Klinik Eines Neuen Gestagens , pp. 171-179
    • Schleußner, E.1    Michels, W.2    Bethge, S.3    Klinger, C.4
  • 20
    • 0026327614 scopus 로고
    • In vitro effect of synthetic progestogens on estrone sulfatase activity in human breast carcinoma
    • Prost-Avallet O, Oursin J, Adessi GL. In vitro effect of synthetic progestogens on estrone sulfatase activity in human breast carcinoma. J Steroid Biochem Molec Biol 1991; 39: 967-73
    • (1991) J Steroid Biochem Molec Biol , vol.39 , pp. 967-973
    • Prost-Avallet, O.1    Oursin, J.2    Adessi, G.L.3
  • 21
    • 80052083991 scopus 로고    scopus 로고
    • In vitro effects of dienogest and other synthetic progestins on estrone sulfatase activity in human placental microsomes and MCF-7 cells
    • submitted
    • Römer W, Oettel M. In vitro effects of dienogest and other synthetic progestins on estrone sulfatase activity in human placental microsomes and MCF-7 cells. Die Pharmazie 1998; submitted
    • (1998) Die Pharmazie
    • Römer, W.1    Oettel, M.2
  • 22
    • 0031024376 scopus 로고    scopus 로고
    • Dienogest, a novel synthetic steroid, overcomes hormone-dependent cancer in a different manner than progestins
    • DOI 10.1002/(SICI)1097-0142(19970101)79: 1<169::AID-CNCR24>3.0. CO;2-1
    • KatsukiY, ShibutaniY, Aoki D, Nozawa S. Dienogest, a novel synthetic steroid, overcomes hormone-dependent cancer in a different manner than progestins. Cancer 1997; 79: 169-76 (Pubitemid 26425523)
    • (1997) Cancer , vol.79 , Issue.1 , pp. 169-176
    • Katsuki, Y.1    Shibutani, Y.2    Aoki, D.3    Nozawa, S.4
  • 23
    • 80052103497 scopus 로고    scopus 로고
    • In vivo effects of dienogest alone or in combination with estradiol valerate or ethinylestradiol on ovarian steroid synthesis and circulating levels of inhibin, SHBG, IGF 1 and IGF-BP 3
    • Schleußner E, Weber A, Albrecht S, Distler W. In vivo effects of dienogest alone or in combination with estradiol valerate or ethinylestradiol on ovarian steroid synthesis and circulating levels of inhibin, SHBG, IGF 1 and IGF-BP 3. Acta Obstet Gynecol Scand 1997; 76(Suppl): P72.50
    • (1997) Acta Obstet Gynecol Scand , vol.76 , Issue.SUPPL. , pp. 7250
    • Schleußner, E.1    Weber, A.2    Albrecht, S.3    Distler, W.4
  • 24
    • 0000257829 scopus 로고
    • Endokrinologische Befunde und die Reaktivität der Hypophyse gegenüber GnRH unter Gestagenmonotherapie der Endometriose mit Dienogest
    • Teichmann AT ed. 2nd edn. Berlin: Walter de Gruyter
    • Köhler G.Wodrig W. Endokrinologische Befunde und die Reaktivität der Hypophyse gegenüber GnRH unter Gestagenmonotherapie der Endometriose mit Dienogest. In Teichmann AT, ed. Dienogest - Präklinik und Klinik eines neuen Gestagens. 2nd edn. Berlin: Walter de Gruyter, 1995: 253-60
    • (1995) Dienogest - Präklinik und Klinik Eines Neuen Gestagens , pp. 253-260
    • Köhler, G.1    Wodrig, W.2
  • 25
    • 0003131003 scopus 로고
    • Stölzner W Studie zur Entwicklung eines geeigneten Modells der Endometriosis externa bei Kaninchen und Ratten und die Effekte von Dienogest und Danazol
    • Oettel M, Bocker Th, Güttner J, Horn M, Stölzner W Studie zur Entwicklung eines geeigneten Modells der Endometriosis externa bei Kaninchen und Ratten und die Effekte von Dienogest und Danazol. Fertilität 1992; 8: 131-5
    • (1992) Fertilität , vol.8 , pp. 131-135
    • Oettel, M.1    Th, B.2    Güttner, J.3    Horn, M.4
  • 27
    • 0031911362 scopus 로고    scopus 로고
    • Reappraisal of progestins in endometriosis therapy
    • DOI 10.1530/eje.0.1380134
    • Kauppila A. Reappraisal of progestins in endometriosis therapy. Eur J Endocrinol 1998; 138: 134-6 (Pubitemid 28131088)
    • (1998) European Journal of Endocrinology , vol.138 , Issue.2 , pp. 134-136
    • Kauppila, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.