Relationships between population size and loss of genetic diversity: Comparisons of experimental results with theoretical predictions

Conservation Genetics

Volumn 1, Issue 1, 2000, Pages 33-43

  Montgomery, Margaret E ^a   Woodworth, Lynn M ^a   Nurthen, Roderick K ^a   Gilligan, Dean M ^a   Briscoe, David A ^a   Frankham, Richard ^a  

^a MACQUARIE UNIVERSITY   (Australia)

Author keywords

Allozymes; Drosophila melanogaster; Effective population size; Genetic diversity; Inversions

Indexed keywords

EID: 0003005696     PISSN: 15660621     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010173401557     Document Type: Article

References (57)

1. Ayala FJ, Campbell CA (1974) Frequency-dependent selection. Annu. Rev. Ecol. Syst., 5, 115-138
2. Ballou JD, Foose TJ (1996) Demographic and genetic management of captive populations. In: Wild Animals in Captivity: Principles and Techniques (eds. Kleiman DG, Allen ME, Thompson KV, Lumpkin S), pp. 263-283. University of Chicago Press, Chicago
3. Ballou J, Lacy RC (1995) Identifying genetically important individuals for management of genetic diversity in pedigreed populations. In: Population Management for Survival and Recovery: Analytical Methods and Strategies in Small Population Conservation (eds. Ballou J, Gilpin M, Foose T), pp. 76-111. Columbia University Press, New York
4. Begun DJ, Aquadro CF (1992) Levels of naturally occurring DNA polymorphism correlate with recombination rates in D. melanogaster. Nature 356, 519-520
5. Borlase SC, Loebel DA, Frankham R, Nurthen RK, Briscoe DA, Daggard GE (1993) Modeling problems in conservation genetics using captive Drosophila populations: consequences of equalization of family sizes. Conserv. Biol., 7, 122-131
6. Briscoe DA, Malpica JM, Robertson A, Smith GJ, Frankham R, Banks RG, and Barker JSF (1992) Rapid loss of genetic variation in large captive populations of Drosophila flies: Implications for the genetic management of captive populations. Conserv. Biol., 6, 416-425
7. Briton J, Nurthen RK, Briscoe DA, Frankham R (1994) Modelling problems in conservation genetics using captive Drosophila populations: Consequences of harems. Biol. Conserv., 69, 267-275
8. Brookfield JFY, Sharp PM (1994) Neutralism and selectionism face up to DNA data. Trend. Genet., 10, 109-111
9. Brown A, Young A, Burdon J, Cristidis L, Clarke G, Coates D, Sherwin W (1997) Genetic Indicators for State of the Environment Reporting. Australia: State of the Environment Technical Paper Series (Environmental Indicators). Department of Environment, Sport and Territories, Canberra, Australia
10. Crow JF, Kimura M (1970) An Introduction to Population Genetics Theory. Harper & Row, New York
11. Cruden D (1949) The computation of inbreeding coefficients in closed populations. J. Hered., 40, 248-251
12. Dobzhansky T, Pavlovsky O (1957) An experimental study of the interaction between genetic drift and natural selection. Evolution, 11, 311-319
13. Dobzhansky T, Ayala FJ, Stebbins GL, and Valentine JW (1977) Evolution. W.H. Freeman, San Francisco
14. Ellstrand NC, Elam DR (1993) Population genetic consequences of small population size: Implications for plant conservation. Annu. Rev. Ecol. Syst., 24, 217-242
15. Eriksson K, Halkka O, Lokki J, Saura A (1976) Enzyme polymorphism in feral, outbred and inbred rats (Rattus norvegicus). Heredity, 37, 341-349
16. Falconer DS, Mackay TFC (1996) Introduction to Quantitative Genetics, 4th edn. Longman, Harlow, England
17. Fitch WM, Atchley WR (1985) Evolution in inbred strains of mice appears rapid. Science, 228, 1169-1175
18. Frankel OH, Soulé ME (1981) Conservation and Evolution. Cambridge University Press, Cambridge
19. Frankham R (1995a) Conservation genetics. Annu. Rev. Genet., 29, 305-327
20. Frankham R (1995b) Effective population size / adult population size ratios in wildlife: a review. Genet. Res., 66, 95-107
21. Frankham R (1996) Relationship of genetic variation to populations size in wildlife. Conserv. Biol., 10, 1500-1508
22. Frankham R (2000) Modeling problems in conservation genetics using laboratory animals. In: Quantitative Methods in Conservation Biology (eds. Person S, Burgman M), pp. 259-273. Springer-Verlag, New York
23. Frankham R, Manning H, Margan SH, David A. Briscoe DA (2000) Does equalisation of family sizes reduce genetic adaptation to captivity? Animal Conservation (in press)
24. Franklin IR (1980) Evolutionary change in small populations. In: Conservation Biology: An Evolutionary Ecological Perspective (eds. Soulé, ME, Wilcox BA), pp. 135-149. Sinauer, Sunderland, MA
25. Gillespie JH (1991) The Causes of Molecular Evolution. Oxford University Press, New York
26. Hey J (1999) The neutralist, the fly and the selectionist. Trends Ecol. Evol., 14, 35-38
27. Hoffmann AA, Parsons PA (1991) Evolutionary Genetics and Environmental Stress. Oxford University Press, Oxford
28. Karl SA, Avise JC (1992) Balancing selection at allozyme loci in oysters: Implications from nuclear RFLPs. Science 256, 100-102
29. Kimura M (1983) The Neutral Theory of Molecular Evolution. Cambridge University Press, Cambridge
30. Kreitman M (1996) The neutral theory is dead. Long live the neutral theory. BioEssays, 18, 678-683
31. Kreitman M, Akashi H (1995) Molecular evidence for natural selection. Annu. Rev. Ecol. Syst., 26, 403-422
32. Latter BDH. (1998) Mutant alleles of small effect are primarily responsible for the loss of fitness with slow inbreeding in Drosophila melanogaster. Genetics 148, 1143-1158
33. Latter BDH, Mulley JC, Reid D, Pascoe L (1995) Reduced genetic load revealed by slow inbreeding in Drosophila melanogaster. Genetics 139, 287-297
34. Leberg PL (1992) Effects of population bottlenecks on genetic diversity as measured by allozyme electrophoresis. Evolution 46, 477-494
35. Lewontin RC (1974) The Genetic Basis of Evolutionary Change. Columbia University Press, New York
36. Lindsley DL, Zimm GG (1992) The Genome of Drosophila melanogaster. Academic Press, San Diego
37. McNeely JA, Miller KR, Reid WV, Mittermeier RA, Werner TB (1990) Conserving the World's Biological Diversity. IUCN, World Resources Institute, Conservation International, WWF-US and the World Bank, Washington, DC
38. Mina, NS, Sheldon, BL, Yoo BH, Frankham R (1991) Heterozygosity at protein loci in inbred and outbred lines of chickens. Poult. Sci., 70, 1864-1872
39. Nei M, Graur D (1984) Extent of protein polymorphism and the neutral mutation theory. Evol. Biol., 17, 73-118
40. Nevo E, Bieles A, Ben-Shlomo R (1984) The evolutionary significance of genetic diversity: ecological, demographic and life history correlates. In: Evolutionary Dynamics of Genetic Diversity (ed. Mani GS), pp. 13-213. Springer-Verlag, Berlin
41. Ohta T (1992) The near neutral theory of molecular evolution. Annu. Rev. Ecol. Syst., 23, 263-286
42. Ohta T (1996) The current significance and standing of neutral and near neutral theories. BioEssays, 18, 673-677
43. Pogson GH, Zouros E (1994) Allozyme and RFLP heterozygosities as correlates of growth rate in the scallop Placopecten magellanicus: a test of the associative overdominance hypothesis. Genetics 137, 221-231
44. Raybould AF, Mogg RJ, CLarke RT (1996) The genetic structure of Beta vulgaris ssp. maritime (sea beet) populations: RFLPs and isozymes show different patterns of gene flow. Heredity, 77, 245-250
45. Richardson BJ, Baverstock PR, Adams M (1986) Allozyme Electrophoresis: A Handbook for Animal Systematics and Population Studies. Academic Press, Sydney, Australia
46. Robertson A (1962) Selection for heterozygotes in small populations. Genetics, 47, 1291-1300
47. Rumball W, Franklin IR, Frankham R, Sheldon BL (1994) Decline in heterozygosity under full-sib and double first-cousin inbreeding in Drosophila melanogaster. Genetics, 136, 1039-1049
48. Ryan BF, Joiner BL (1994) MINITAB Handbook, 3rd edn. Duxbury Press, Belmont, California
49. Satta Y, O'Huigin C, Takahata N, Klein J. (1994) Intensity of natural selection at the major histocompatibility complex loci. Proc. Natl. Acad. Sci. USA, 91, 7184-7188
50. Sing CF, Brewer GJ, Thirtle B (1973) Inherited biochemical variation in Drosophila melanogaster: Noise or signal? I. Single-locus analyses. Genetics, 75, 381-404
51. Soulé ME (1976) Allozyme variation, its determinants in space and time. In: Molecular Evolution (ed. Ayala FJ), pp. 60-77. Sinauer, Sunderland, MA
52. Soulé ME, Gilpin M, Conway W, Foose T (1986) The millenium ark: how long a voyage, how many staterooms, how many passengers? Zoo Biol., 5, 101-113
53. Strauss SH (1986) Heterosis at allozyme loci under inbreeding and crossbreeding in Pinus attenuata. Genetics, 113, 115-134
54. Woodworth LM (1996) Population Size in Captive Breeding Programs. PhD thesis, Macquarie University, Sydney, Australia
55. Woodworth LM, Montgomery ME, Nurthen RK, Briscoe DA, Frankham R (1994) Modelling problems in conservation genetics using Drosophila: consequences of fluctuating population sizes. Mol. Ecol., 3, 393-399
56. Wright S (1931) Evolution in Mendelian populations. Genetics, 16, 97-159
57. Yeh FC, Scheinberg E (1972) Inbreeding as a control of biochemical polymorphism in populations of Tribolium castaneum. Can. J. Genet. Cytol., 14, 741