-
1
-
-
0023949179
-
Combinatorial cassette mutagenesis as a probe of the informational content of protein sequences
-
Reidhaar-Olson, J.F. & Sauer, R.T. (1988). Combinatorial cassette mutagenesis as a probe of the informational content of protein sequences. Science 241, 53-57.
-
(1988)
Science
, vol.241
, pp. 53-57
-
-
Reidhaar-Olson, J.F.1
Sauer, R.T.2
-
2
-
-
0001586362
-
Identifying determinants of folding and activity for a protein of unknown structure
-
Bowie, J.U. & Sauer, R.T. (1989). Identifying determinants of folding and activity for a protein of unknown structure. Proc. Natl. Acad. Sci. USA 86, 2152-2156.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 2152-2156
-
-
Bowie, J.U.1
Sauer, R.T.2
-
3
-
-
0024507791
-
Alternative packing arrangements in the hydrophobic core of λ repressor
-
Lim, W.A. & Sauer, R.T. (1989). Alternative packing arrangements in the hydrophobic core of λ repressor. Nature 339, 31-36.
-
(1989)
Nature
, vol.339
, pp. 31-36
-
-
Lim, W.A.1
Sauer, R.T.2
-
4
-
-
0024307543
-
Mutational analysis of the fine specificity of binding of monoclonal antibody 51F to λ repressor
-
Breyer, R.M. & Sauer, R.T. (1989). Mutational analysis of the fine specificity of binding of monoclonal antibody 51F to λ repressor. J. Biol. Chem. 264, 13355-13360.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 13355-13360
-
-
Breyer, R.M.1
Sauer, R.T.2
-
5
-
-
23444436172
-
Protein design by binary patterning of polar and nonpolar amino acids
-
Kamtekar, S., Schiffer, J.M., Xiong, H., Babik, J.M. & Hecht, M.H. (1993). Protein design by binary patterning of polar and nonpolar amino acids. Science 262, 1680-1685.
-
(1993)
Science
, vol.262
, pp. 1680-1685
-
-
Kamtekar, S.1
Schiffer, J.M.2
Xiong, H.3
Babik, J.M.4
Hecht, M.H.5
-
6
-
-
0027211894
-
Additivity of mutant effects assessed by binomial mutagenesis
-
Gregoret, L. & Sauer, R.T. (1993). Additivity of mutant effects assessed by binomial mutagenesis. Proc. Natl. Acad. Sci. USA 90, 4246-4250.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4246-4250
-
-
Gregoret, L.1
Sauer, R.T.2
-
7
-
-
0027180729
-
Probing the roles of residues at the e and g positions of the GCN4 leucine zipper by combinatorial mutagenesis
-
Hu, J.C., Newell, N.E., Tidor, B. & Sauer, R.T. (1993). Probing the roles of residues at the e and g positions of the GCN4 leucine zipper by combinatorial mutagenesis. Protein Sci. 2,1072-1084.
-
(1993)
Protein Sci.
, vol.2
, pp. 1072-1084
-
-
Hu, J.C.1
Newell, N.E.2
Tidor, B.3
Sauer, R.T.4
-
8
-
-
0025370163
-
Functionally acceptable substitutions in two α-helical regions of λ repressor
-
Reidhaar-Olson, J.F. & Sauer, R.T. (1990). Functionally acceptable substitutions in two α-helical regions of λ repressor. Proteins 7, 306-316.
-
(1990)
Proteins
, vol.7
, pp. 306-316
-
-
Reidhaar-Olson, J.F.1
Sauer, R.T.2
-
9
-
-
0025363984
-
Deciphering the message in protein sequences: Tolerance to amino acid substitutions
-
Bowie, J.U., Reidhaar-Olson, J.F., Lim, W.A. & Sauer, R.T. (1990). Deciphering the message in protein sequences: tolerance to amino acid substitutions. Science 247, 1306-1310.
-
(1990)
Science
, vol.247
, pp. 1306-1310
-
-
Bowie, J.U.1
Reidhaar-Olson, J.F.2
Lim, W.A.3
Sauer, R.T.4
-
10
-
-
0027265713
-
The role of turns in the structure of an alpha-helical protein
-
Brunet, A.P., Huang, E.S., Huffine, M.E., Loeb, J.E., Weltman, R.J. & Hecht, M.H. (1993). The role of turns in the structure of an alpha-helical protein. Nature 364, 355-358.
-
(1993)
Nature
, vol.364
, pp. 355-358
-
-
Brunet, A.P.1
Huang, E.S.2
Huffine, M.E.3
Loeb, J.E.4
Weltman, R.J.5
Hecht, M.H.6
-
11
-
-
0027815614
-
An analysis of packing in the protein folding problem
-
Richards, F.M. & Lim, W. (1993). An analysis of packing in the protein folding problem. Q. Rev. Biophys. 26, 423-498.
-
(1993)
Q. Rev. Biophys.
, vol.26
, pp. 423-498
-
-
Richards, F.M.1
Lim, W.2
-
12
-
-
0025908265
-
The role of internal packing interactions in determining the structure and stability of a protein
-
Lim, W.A. & Sauer, R.T. (1991). The role of internal packing interactions in determining the structure and stability of a protein. J. Mol. Biol. 219, 359-376.
-
(1991)
J. Mol. Biol.
, vol.219
, pp. 359-376
-
-
Lim, W.A.1
Sauer, R.T.2
-
13
-
-
0026766573
-
The structural and energetic consequences of disruptive mutations in a protein core
-
Lim, W.A., Farruggio, D.C. & Sauer, R.T. (1992). The structural and energetic consequences of disruptive mutations in a protein core. Biochemistry 31, 4324-4333.
-
(1992)
Biochemistry
, vol.31
, pp. 4324-4333
-
-
Lim, W.A.1
Farruggio, D.C.2
Sauer, R.T.3
-
15
-
-
0025598302
-
Sequence requirements for coiled-coil interactions: Analysis using X repressor-GCN4 leucine zipper fusions
-
Hu, J.C., O'Shea, E.K., Kim, P.S. & Sauer, R.T. (1990). Sequence requirements for coiled-coil interactions: analysis using X repressor-GCN4 leucine zipper fusions. Science 250, 1400-1403.
-
(1990)
Science
, vol.250
, pp. 1400-1403
-
-
Hu, J.C.1
O'Shea, E.K.2
Kim, P.S.3
Sauer, R.T.4
-
16
-
-
0027450286
-
Exploring the interface between the N- and C-terminal helices of cytochrome c by random mutagenesis within the C-terminal helix
-
Fredericks, Z.L. & Pielak, G.J. (1993). Exploring the interface between the N- and C-terminal helices of cytochrome c by random mutagenesis within the C-terminal helix. Biochemistry 32, 929-936.
-
(1993)
Biochemistry
, vol.32
, pp. 929-936
-
-
Fredericks, Z.L.1
Pielak, G.J.2
-
17
-
-
0027716138
-
The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme
-
Baldwin, E.P., Hajiseyedjavadi, O., Baase, W.A. & Matthews, B.W. (1993). The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science 262, 1715-1718.
-
(1993)
Science
, vol.262
, pp. 1715-1718
-
-
Baldwin, E.P.1
Hajiseyedjavadi, O.2
Baase, W.A.3
Matthews, B.W.4
-
18
-
-
0028608066
-
Redesigning the hydrophobic core of a four-helix-bundle protein
-
Munson, M., O'Brien, R., Sturtevant, J.M. & Regan, L. (1994). Redesigning the hydrophobic core of a four-helix-bundle protein. Protein Sci. 3, 2015-2022.
-
(1994)
Protein Sci.
, vol.3
, pp. 2015-2022
-
-
Munson, M.1
O'Brien, R.2
Sturtevant, J.M.3
Regan, L.4
-
19
-
-
0028858499
-
De novo design of the hydrophobic cores of proteins
-
Desjarlais, J.R. & Handel, T.M. (1995). De novo design of the hydrophobic cores of proteins. Protein Sci. 4, 2006-2018.
-
(1995)
Protein Sci.
, vol.4
, pp. 2006-2018
-
-
Desjarlais, J.R.1
Handel, T.M.2
-
20
-
-
0029980972
-
Active barnase variants with completely random hydrophobic cores
-
in press
-
Axe, D.D., Foster, N.W. & Fersht, A. (1996). Active barnase variants with completely random hydrophobic cores. Proc. Natl. Acad. Sci. USA in press.
-
(1996)
Proc. Natl. Acad. Sci. USA
-
-
Axe, D.D.1
Foster, N.W.2
Fersht, A.3
-
21
-
-
0028940706
-
Critical side-chain interactions at a subunit interface in the Arc represser dimer
-
Milla, M.E. & Sauer, R.T. (1995). Critical side-chain interactions at a subunit interface in the Arc represser dimer. Biochemistry 34, 3344-3351.
-
(1995)
Biochemistry
, vol.34
, pp. 3344-3351
-
-
Milla, M.E.1
Sauer, R.T.2
-
22
-
-
0028147533
-
The crystal structure of a mutant protein with altered but improved hydrophobic core packing
-
Lim, W.A., Hodel, A., Sauer, R.T. & Richards, P.M. (1994). The crystal structure of a mutant protein with altered but improved hydrophobic core packing. Proc. Natl. Acad. Sci. USA 91, 423-427.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 423-427
-
-
Lim, W.A.1
Hodel, A.2
Sauer, R.T.3
Richards, P.M.4
-
23
-
-
0028204490
-
Do salt bridges stabilize proteins? a continuum electrostatic analysis
-
Hendsch, Z.S. & Tidor, B. (1994). Do salt bridges stabilize proteins? A continuum electrostatic analysis. Protein Sci. 3, 211-226.
-
(1994)
Protein Sci.
, vol.3
, pp. 211-226
-
-
Hendsch, Z.S.1
Tidor, B.2
-
24
-
-
0029008590
-
A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil
-
Lumb, K.J. & Kim, P.S. (1995). A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil. Biochemistry 34, 8642-8648.
-
(1995)
Biochemistry
, vol.34
, pp. 8642-8648
-
-
Lumb, K.J.1
Kim, P.S.2
-
25
-
-
0029564595
-
Are buried salt bridges important for protein stability and conformational specificity
-
Waldburger, C.D., Schildbach, J.F. & Sauer, R.T. (1995). Are buried salt bridges important for protein stability and conformational specificity. Nature Struct. Biol. 2, 122-128.
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 122-128
-
-
Waldburger, C.D.1
Schildbach, J.F.2
Sauer, R.T.3
-
26
-
-
0029966342
-
Barriers to protein folding: Formation of buried polar interactions is a slow step in acquisition of structure
-
in press
-
Waldburger, C.D., Jonsson, T. & Sauer, R.T. (1996). Barriers to protein folding: formation of buried polar interactions is a slow step in acquisition of structure. Proc. Natl. Acad. Sci. USA in press.
-
(1996)
Proc. Natl. Acad. Sci. USA
-
-
Waldburger, C.D.1
Jonsson, T.2
Sauer, R.T.3
-
27
-
-
0028882589
-
P22 Arc repressor: Transition state properties inferred from mutational effects on the rates of protein unfolding and refolding
-
Milla, M.E., Brown, B.M., Waldburger, C.D. & Sauer, R.T. (1995). P22 Arc repressor: transition state properties inferred from mutational effects on the rates of protein unfolding and refolding. Biochemistry 34, 13914-13919.
-
(1995)
Biochemistry
, vol.34
, pp. 13914-13919
-
-
Milla, M.E.1
Brown, B.M.2
Waldburger, C.D.3
Sauer, R.T.4
-
28
-
-
0029049321
-
Extremely rapid protein folding in the absence of intermediates
-
Schindler, T., Herrler, M., Marahiel, M.A. & Schmid, F.X. (1995). Extremely rapid protein folding in the absence of intermediates. Nature Struct. Biol. 2, 663-673.
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 663-673
-
-
Schindler, T.1
Herrler, M.2
Marahiel, M.A.3
Schmid, F.X.4
-
29
-
-
0029868589
-
Nonlinear free energy relationships in Arc repressor unfolding imply existence of unstable, native-like folding intermediates
-
in press
-
Jonsson, T., Waldburger, C.D. & Sauer, R.T. (1996). Nonlinear free energy relationships in Arc repressor unfolding imply existence of unstable, native-like folding intermediates. Biochemistry in press.
-
(1996)
Biochemistry
-
-
Jonsson, T.1
Waldburger, C.D.2
Sauer, R.T.3
-
30
-
-
0028218304
-
Folded proteins occur frequently in libraries of random amino acid sequences
-
Davidson, A.R. & Sauer, R.T. (1994). Folded proteins occur frequently in libraries of random amino acid sequences. Proc. Natl. Acad. Sci. USA 91, 2146-2150.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2146-2150
-
-
Davidson, A.R.1
Sauer, R.T.2
-
31
-
-
0029120253
-
Cooperatively folded proteins in random sequence libraries
-
Davidson, A.R., Lumb, K.J. & Sauer, R.T. (1995). Cooperatively folded proteins in random sequence libraries. Nature Struct. Biol. 2, 856-863.
-
(1995)
Nature Struct. Biol.
, vol.2
, pp. 856-863
-
-
Davidson, A.R.1
Lumb, K.J.2
Sauer, R.T.3
|