A comparison of mutational specificity of mutations induced by S9-activated B[a]P and benzo[a]pyrene-7,8-diol-9,10-epoxide at the endogenous aprt gene in CHO cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 423, Issue 1-2, 1999, Pages 23-32

  Yang, Haiyan ^a   Mazur Melnyk, Mary ^b   De Boer, Johan G ^a   Glickman, Barry W ^a  

^a UNIVERSITY OF VICTORIA   (Canada)

^b Connaught Laboratories ^*  (Canada)

Author keywords

aprt; Benzo a pyrene; Benzo a pyrene diol epoxide; Mutation spectrum

Indexed keywords

7,8 DIHYDROXYBENZO[A]PYRENE 9,10 OXIDE; ADENINE; BENZO[A]PYRENE; GUANINE; POLYCYCLIC AROMATIC HYDROCARBON;

ANIMAL CELL; ARTICLE; CHO CELL; CODON; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENE MUTATION; METABOLITE; NONHUMAN; ONCOGENE C H RAS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ADENINE PHOSPHORIBOSYLTRANSFERASE; ANIMALS; BENZO(A)PYRENE; CARCINOGENS; CELLS, CULTURED; CHO CELLS; CRICETINAE; DNA MUTATIONAL ANALYSIS; HUMANS; LIVER EXTRACTS; MUTAGENESIS, SITE-DIRECTED; MUTAGENS; RATS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0002955611     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(98)00221-8     Document Type: Article

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