Nebulisation of surfactants in an animal model of neonatal respiratory distress

Archives of Disease in Childhood: Fetal and Neonatal Edition

Volumn 78, Issue 1, 1998, Pages

  Fok, Tai Fai ^a   Al Essa, Mazen ^a   Dolovich, Myrna ^a   Rasid, Farid ^a   Kirpalani, Haresh ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Nebuliser; Rabbits; Respiratory distress syndrome; Surfactant

Indexed keywords

CARBON DIOXIDE; LUNG SURFACTANT; OXYGEN; TECHNETIUM 99M;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL CARBON DIOXIDE TENSION; ARTERIAL OXYGEN TENSION; ARTICLE; CONTROLLED STUDY; GAS EXCHANGE; INHALATIONAL DRUG ADMINISTRATION; LUNG DEPOSIT; LUNG LAVAGE; MEDICAL NEBULIZER; NEBULIZATION; NEONATAL RESPIRATORY DISTRESS SYNDROME; NONHUMAN; PRIORITY JOURNAL; RABBIT;

EID: 0002719728     PISSN: 13592998     EISSN: 14682052     Source Type: Journal    
DOI: 10.1136/fn.78.1.F3     Document Type: Article

References (38)

1. Soll RF, Sinclair JC, Bracken MB. Meta-analysis of surfactant trials: the effect of prophylactic surfactant vs surfactant treatment of established RDS. Pediatr Res 1993;33:276A.
2. Khammash H, Perlman M, Wojtulewicz J, Dunn M. Surfactant therapy in full term neonates with severe respiratory failure. Pediatrics 1993;92:135-9.
3. Auten RL, Notter RH, Kendig JW, Davis JM, Shapiro DL. Surfactant treatment of full-term newborns with respiratory failure. Pediatrics 1991;87:101-7.
4. Findlay RD, Taeusch HW, Walther FJ. Surfactant therapy for meconium aspiration syndrome. Pediatrics 1996;97:48-52.
5. Shindler M, Bohn D, Bryan C, Barker G. The effect of surfactant in pediatric patients with respiratory failure. Clin Invest Med 1992;15:108A.
6. Richman PS, Spragg RG, Robertson B, Merritt TA, Curstedt T. The adult respiratory distress syndrome: first trials with surfactant replacement. Eur Respir J 1989;3(Suppl):109-11.
7. Weg JG, Balk RA, Tharratt RS, et al. Safety and potential efficacy of an aerosolized surfactant in human sepsis-induced adult respiratory distress syndrome. JAMA 1994;272:1433-8.
8. Lachmann B. Animal models and clinical pilot studies of surfactant replacement in adult respiratory distress syndrome. Eur Respir J 1989;3 (Suppl):98-103.
9. Van Der Bleek J, Plotz FB, Van Overbeek FM, et al. Distribution of exogenous surfactant in rabbits with severe respiratory failure: the effect of volume. Pediatr Res 1993;34:154-8.
10. Segerer H, Van Gelder W, Angenent FW, et al. Pulmonary distribution and efficacy of exogenous surfactant in lung-lavaged rabbits are influenced by the instillation technique. Pediatr Res 1993;34:490-4.
11. Cowan F, Whitelaw A, Wertheim D, Silverman M. Cerebral blood flow velocity changes after rapid administration of surfactant. Arch Dis Child 1991;66:1105-9.
12. Gunkel JH, Banks PL. Surfactant therapy and intracranial hemorrhage: review of the literature and results of new analyses. Pediatrics 1993;92:775-86.
13. Marks LB, Notter RH, Oberdorster G, McBridge JT. Ultrasonic and jet aerosolization of phospholipids and the effects on surface activity. Pediatr Res 1993;17:742-7.
14. Lewis JF, Ikegami M, Jobe AH, Absolom D. Physiologic responses and distribution of aerosolized surfactant (Survanta) in a nonuniform pattern of lung injury. Am Rev Respir Dis 1993;147:1364-70.
15. Lewis JF, McCaig L. Aerosolized versus instilled exogenous surfactant in a nonuniform pattern of lung injury. Am Rev Respir Dis 1993;148:1187-93.
16. Lewis JF, Tabor B, Ikegami M, Jobe AH, Joseph M, Absolom D. Lung function and surfactant distribution in saline-lavaged sheep given instilled vs. nebulised surfactant. J Appl Physiol 1993;74:1256-64.
17. Lewis JF, Ikegami M, Jobe AH, Tabor B. Aerosolized surfactant treatment of preterm lambs. J Appl Physiol 1991;70:869-76.
18. Lewis J, Ikegami M, Higuchi R, Jobe A, Absolom D. Nebulised vs. instilled exogenous surfactant in an adult lung injury model. J Appl Physiol 1991;71:1270-6.
19. Anzueto A, Baughman RP, Guntupalli KK, et al. Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome. N Engl J Med 1996;334:1417-21.
20. Thomas SH, O'Doherty MJ, Fidler HM, Page CJ, Treacher DF, Nunan TO. Pulmonary deposition of a nebulised aerosol during mechanical ventilation. Thorax 193;48:154-9.
21. Fuller HD, Dolovich MB, Posmituck G, Wong Pack W, Newhouse MT. Pressurized aerosol versus jet aerosol delivery to mechanically ventilated patients. Comparison of dose to the lungs. Am Rev Respir Dis 1990;141:440-4.
22. MacIntyre NR, Silver RM, Miller CW, Schuler F, Coleman E. Aerosol delivery in intubated, mechanically ventilated patients. Crit Care Med 1985;13:81-4.
23. Cameron D, Arnot R, Clay M, Silverman M. Aerosol delivery in neonatal ventilator circuits: a rabbit lung model. Pediatr Pulmonol 1991;10:208-13.
24. Arnon S, Grigg J, Nikander K, Silverman M. Delivery of micronized budesonide suspension by metered dose inhaler and jet nebuliser into neonatal ventilator circuit. Pediatr Pulmonol 1992;13:172-5.
25. Grigg J, Arnon S, Jones T, Clarke A, Silverman M. Delivery of therapeutic aerosols to intubated infants. Arch Dis Child 1992;67:25-30.
26. Watterberg KL, Clark AR, Kelly HW, Murphy S. Delivery of aerosolized medication to intubated babies. Pediatr Pulmonol 1991;10:136-41.
27. Cameron D, Clay M, Silverman M. Evaluation of nebulizers for use in neonatal ventilator circuits. Crit Care Med 1990;18:866-70.
28. Flavin M, MacDonald M, Dolovich M, Coates G, O'Brodovich H. Aerosol delivery to the rabbit lung with an infant ventilator. Pediatr Pulmonol 1986;2:35-9.
29. Fok TF, Monkman S, Dolovich M, et al. Efficiency of aerosol medication delivery from a metered dose inhaler versus jet nebuliser in infants with bronchopulmonary dysplasia. Pediatr Pulmonol 1996; 21:301-9.
30. Thomas SHL, O'Doherty MJ, Page CJ, Treacher DF, Nunan TO. Delivery of ultrasonic nebulised aerosols to a lung model during mechanical ventilation. Am Rev Respir Dis 1993;148:872-7.
31. O'Doherty MJ, Thomas SH, Page CJ, Treacher DF, Nunan TO. Delivery of a nebulised aerosol to a lung model during mechanical ventilation. Effect of ventilator settings and nebuliser type, position, and volume of fill. Am Rev Respir Dis 1992;146:383-8.
32. Thomas SH, O'Doherty MJ, Page CJ, Treacher DF, Nunan TO. Delivery of ultrasonic nebulised aerosols to a lung model during mechanical ventilation. Am Rev Respir Dis 1993;148:872-7.
33. Davis JM, Russ GA, Dickerson B, Greenspan BS. Short term distribution kinetics of intratracheally administered exogenous lung surfactant. Pediatr Res 1992;31:445-50.
34. Li WZ, Chen WM, Kobayashi T. Aerosolized surfactant reverses respiratory failure in lung-lavaged rats. Acta Anaesthesiol Scand 1994;38:82-8.
35. Niven RW, Ip AY, Mittelman S, Prestrelski SJ, Arakawa T. Some factors associated with the ultrasonic nebulization of protein. Pharm Res 1995;12:53-9.
36. Boucher RMG, Kreuter J. The fundamentals of the ultrasonic atomization of medical solutions. Ann Allergy 1968;26:591-600.
37. Spragg RG, Gilliard N, Richman P, et al. Acute effects of a single dose of porcine surfactant on patients with adult respiratory distress syndrome. Chest 1994;105:195-202.
38. Gregory TJ, Steinberg KP, Spragg R, et al. Bovine surfacant therapy for patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 1997;155:1309-15.