AT1-receptors in the central nervous system

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 2, Issue SUPPL. 1, 2001, Pages

  Allen, Andrew M ^a   Giles, Michelle E ^a   Lee, JooHyung ^a   Oldfield, Brian J ^a   Mendelsohn, Frederick A O ^a   McKinley, Michael J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Angiotensin; Brain; Receptors

Indexed keywords

EID: 0002379383     PISSN: 14703203     EISSN: None     Source Type: Journal    
DOI: 10.1177/14703203010020011701     Document Type: Review

References (131)

1. Phillips MI. Functions of angiotensin in the central nervous system. Ann Rev Physiol 1987;49:413-35.
2. Fischer-Ferraro C, Nahmod VE, Goldstein DJ, Finkielman S. Angiotensin and renin in rat and dog brain. J Exp Med 1971; 133:353-61.
3. Ganten D, Minnich JL, Granger P et al. Angiotensin-forming enzyme in the brain tissue. Science 1971;173:64-5.
4. Hirose S, Yokosawa H, Inagami T. Immunochemical identification of renin in rat brain and distinction from acid proteases. Nature 1978;274:392-3.
5. Campbell DJ. Angiotensin peptides in the brain. Adv Exp Med Biol 1995;377:349-55.
6. Fuxe K, Ganten D, Hokfelt T, Bolme P. Immunohistochemical evidence for the existence of angiotensin II-containing nerve terminals in the brain and spinal cord of the rat. Neurosci Lett 1976;2:229-34.
7. Lind RW, Swanson LW, Ganten D. Organization of angiotensin II immunoreactive cells and fibres in the rat central nervous system. Neuroendocrinology 1985;40:2-24.
8. Allen AM, Paxinos G, Song KF, Mendelsohn FAO. Localization of angiotensin receptor binding sites in the rat brain. In: Bjorkland A, Hokfelt T, Kuhar MJ (eds). Handbook of Chemical Neuroanatomy: Neuropeptide receptors in the CNS. Amsterdam: Elsevier, 1992;11:1-35.
9. 2) receptor mRNAs in the adult rat brain: a functional anatomical review. Front Neuroendocrinol 1997;18:383-439.
10. Hilgenfeld U. Angiotensinogen in rat cerebrospinal fluid. Clin Exper Hypertens 1984;6:1815-24.
11. Timmermans PBMW, Wong PC, Chiu AT et al. Angiotensin II receptors and angiotensin II receptor antagonists. Pharmacol Rev 1993;45:205-51.
12. Murphy TJ, Alexander RW, Griendling KK, Runge MS, Bernstein KE. Isolation of a cDNA encoding the vascular type-I angiotensin II receptor. Nature 1991;351:233-6.
13. Sasaki K, Yamano Y, Bardhan S et al. Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor. Nature 1991;351:230-3.
14. Kambayashi Y, Bardhan S, Takahashi K et al. Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition. J Biol Chem 1993;268:24543-6.
15. Mukoyama M, Nakajima M, Horiuchi M, Sasamura H, Pratt RE, Dzau VJ. Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors. J Biol Chem 1993;268:24539-42.
16. 2-receptor mediates inhibition of cell proliferation in coronary endothelial cells. J Clin Invest 1995;95:651-7.
17. Yamada T, Horiuchi M, Dzau VJ. Angiotensin II type 2 receptor mediates programmed cell death. Proc Natl Acad Sci USA 1996; 93:156-60.
18. Horiuchi M, Akishita M, Dzau VJ. Recent progress in angiotensin II type 2 receptor research in the cardiovascular system. Hypertension 1999; 33:613-21.
19. Moeller IM, Allen AM, Chai SY, Zhuo J, Mendelsohn FAO. Bioactive angiotensin peptides. J Hum Hypertens 1998;12: 289-93.
20. Rowe BP, Grove KL, Saylor DL, Speth RC. Angiotensin II receptor subtypes in the rat brain. Eur J Pharmacol 1990;186:339-42.
21. Wamsley JK, Herblin WF, Hunt M. Evidence for the presence of angiotensin II type receptors in brain. Brain Res Bull 1990;25:397-400.
22. Song K, Allen AM, Paxinos G, Mendelsohn FAO. Angiotensin II receptor subtypes in rat brain. Clin Exper Pharmacol Physiol 1991;18:93-6.
23. Song K, Allen AM, Paxinos G, Mendelsohn FAO. Mapping of angiotensin II receptor subtype heterogeneity in rat brain. J Comp Neurol 1992;316:467-84.
24. Bunnemann B, Iwai N, Metzger R, Fuxe K, Inagami T, Ganten D. The distribution of angiotensin II AT1 receptor subtype mRNA in the rat brain. Neurosci Lett 1992;142:155-8.
25. Lenkei Z, Corvol P, Llorens-Cortes C. The angiotensin receptor subtype AT1A predominates in rat forebrain areas involved in blood pressure, body fluid homeostasis and neuroendocrine control. Mol Brain Res 1995;30:53-60.
26. Lenkei Z, Palkovits M, Corvol P, Llorens-Cortes C. Distribution of angiotensin II type-2 receptor (AT2) mRNA expression in the adult rat brain. J Comp Neurol 1996;373:322-39.
27. Giles ME, Fernley RT, Nakamura Y et al. Characterization of a specific antibody to the rat AT1 receptor. J Histochem Cytochem 1999;47:507-15.
28. Aldred GP, Chai SY, Song K, Zhuo J, MacGregor DP, Mendelsohn FAO. Distribution of angiotensin II receptor subtypes in the rabbit brain. Regul Pept 1993;44:119-30.
29. MacGregor DP, Murone C, Song K, Allen AM, Paxinos G, Mendelsohn FAO. Angiotensin II receptor subtypes in the human central nervous system. Brain Res 1995;675:231-40.
30. Barnes JM, Steward U, Barber PC, Barnes NM. Identification and characterization of angiotensin II receptor subtypes in human brain. Eur J Pharmacol 1993;231:251-8.
31. Allen AM, Oldfield BJ, Giles ME, Paxinos G, McKinley MJ, Mendelsohn FAO. Localization of angiotensin receptors in the nervous system. In: Quirion R, Bjorklund A, Hokfelt T (eds). Handbook of Chemical Neuroanatomy. Amsterdam: Elsevier, 2000;79-124.
32. Allen AM, MacGregor DP, McKinley MJ, Mendelsohn FAO. Angiotensin II receptors in the human brain. Reg Pept 1999;79:1-7.
33. Hein L, Barch GS, Pratt RE, Dzau VJ, Kobilka BK. Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in mice. Nature 1995;377:744-7.
34. IchikiT, Labosky PA, Shiota C et al. Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor. Nature 1995;377:748-50.
35. Bickerton RK, Buckley JP. Evidence of a central mechanism in angiotensin-induced hypertension. Proc Soc Exper Biol Med 1961;106:834-6.
36. Dickinson CJ, Lawrence JR. A slowly developing pressor response to small concentrations of angiotensin: its bearing on the pathogenesis of chronic renal hypertension. Lancet 1963;1:1354-6.
37. Scroop GC, Lowe RD. Efferent pathways of the cardiovascular response to vertebral artery infusions of angiotensin in the dog. Clin Sci 1969;37:605-19.
38. Ferrario CM, Dickinson CJ, McCubbin JW. Central vasomotor stimulation by angiotensin. Clin Sci 1970;39:239-43.
39. Ferrario CM, Gildenberg PL, McCubbin JW. Cardiovascular effects of angiotensin mediated by the central nervous system. Circ Res 1972;30(3):257-62.
40. Fukiyama K. Central action of angiotensin and hypertension increased vasomotor outflow by angiotensin. Jpn Circ J 1972;36:599-603.
41. Bonjour JP, Malvin RL. Stimulation of ADH release by the renin-angiotensin system. Am J Physiol 1970;218:1555-9.
42. Lumbers ER, McClosky DI, Potter EK. Inhibition by angiotensin II of baroreceptor-evoked activity in cardiac vagal efferent nerves in the dog. J Physiol 1979;294:69-80.
43. Guo GB, Abboud FM. Angiotensin II attenuates baroreflex control of heart rate and sympathetic activity. Am J Physiol 1984;246:H80-H89.
44. Stein RD, Stephenson RB, Weaver LC. Central actions of angiotensin II oppose baroreceptor-induced sympathoinhibition. Am J Physiol 1984;246:R13-R19.
45. Keil LC, Summy-Long J, Severs WB. Release of vasopressin by angiotensin II. Endocrinology 1975;96:1063-8.
46. Brooks VL. Interactions between angiotensin II and the sympathetic nervous system in the long-term control of arterial pressure. Clin Exper Pharmacol Physiol 1997;24:83-90.
47. DiBona GF, Jones SY, Brooks VL. Ang II receptor blockade and arterial baroreflex regulation of renal nerve activity in cardiac failure. Am J Physiol 1995;269:R1189-R1196.
48. Dibner-Dunlap ME, Smith ML, Kinugawa T, Thames MD. Enalaprilat augments arterial and cardiopulmonary baroreflex control of sympathetic nerve activity in patients with heart failure. Am Coll Cardiol 1996;27:358-64.
49. Xu L, Brooks VL. Ang II chronically supports renal and lumbar sympathetic activity in sodium-deprived, conscious rats. Am J Physiol 1996;271:H2951-H2958.
50. Heesch CM, Crandall ME, Turbek JA. Converting enzyme inhibitors cause pressure-independent resetting of baroreflex control of sympathetic outflow. Am J Physiol 1996;270:R728-R737.
51. Mangiapane ML, Simpson JB. Subfornical organ lesions reduce the pressor effects of systemic angiotensin. Neuroendocrinology 1980;31:380-84.
52. Gildenberg PL, Ferrario CM, McCubbin JW. Two sites of cardiovascular actions of angiotensin II in the brain of the dog. Clin Sci 1973;44:417-22.
53. Lewis GP, Reit E. The action of angiotensin and bradykinin on the superior cervical ganglion of the cat. J Physiol 1965;179:538-53.
54. Zimmerman BG. Effect of acute sympathectomy on responses to angiotensin and norepinephrine. Circ Res 1962; 11:78087.
55. Hughes J, Roth RH. Evidence that angiotensin enhances transmitter release during sympathetic nerve stimulation. Br J Pharmacol 1971; 41:239-55.
56. Fitzsimons JT. The role of a renal thirst factor in drinking induced by extracellular stimuli. J Physiol (London) 1969; 201:349-68.
57. Fitzsimons JT, Simons B. The effect on drinking in the rat of intravenous infusion of angiotensin, given alone or in combination with other stimuli of thirst. J Physiol 1969;203:45-57.
58. Simpson JB, Epstein AN, Cammardo JS. Localization of receptors for the dipsogenic action of angiotensin II in the subfornical organ of rat. J Comp Physiol Psychol 1978;92:581-608.
59. Thrasher TN. Circumventricular organs, thirst, and vasopressin secretion. In: Schrier RW (ed). Vasopressin. New York: Raven Press, 1985.
60. McKinley MJ, Badoer E, Oldfield BJ. Intravenous angiotensin II induces Fos-immunoreactivity in circumventricular organs of the lamina terminalis. Brain Res 1992;294:295-300.
61. Cunningham JT, Beltz TG, Johnson RF, Johnson AK. The effects of ibotenate lesions of the median preoptic nucleus on experimentally induced and circadian drinking behaviours in rats. Brain Res 1992;580:325-30.
62. Phillips PA, Rolls BJ, Ledingham JG. Angiotensin II-induced thirst and vasopressin release in man. Clin Sci 1995;68:669-74.
63. Robinson MM, Evered MD. Pressor action of intravenous angiotensin II reduces drinking in rats. Am J Physiol 1987;252:R754-R759.
64. Rogers PW, Kurzman NA. Renal failure, uncontrollable thirst and hyper-reninaemia. Cessation of thirst with bilateral nephtrectomy. JAMA 1973;225:1236-8.
65. Yamamoto T, Shimuzu M, Morioka M. Role of angiotensin II in the pathogenesis of hyperdipsia in chronic renal failure. JAMA 1986;25:604-8.
66. Reid IA. Actions of angiotensin II on the brain: mechanisms and physiologic role. Am J Physiol 1984;246:F533-F543.
67. Miselis RR. The efferent projections of the subfornical organ of the rat: A circumventricular organ with a neural network subserving water balance. Brain Res 1981;230:1-23.
68. Lind RW, van Hoesen GW, Johnson AK. An HRP study of the connections of the subfornical organ of the rat. J Comp Neurol 1982;210:265-77.
69. Mangiapane ML, Thrasher TN, Keil LC, Simpson JG, Ganong WF. Role for the subfornical organ in vasopressin release. Brain Res Bull 1984;13:43-7.
70. Reid IA, Brooks VL, Rudolph CD, Keil LC. Analysis of the action of angiotensin on the central nervous system of conscious dogs. Am J Physiol 1982;243:R82-R91.
71. Ganong WF, Murakami K. The role of angiotensin II in the regulation of ACTH release. Ann NY Acad Sci 1987;512:176-86.
72. Findlay ALR, Epstein AN. Increased sodium intake is somehow induced in rats by intravenous angiotensin II. Horm Behav 1980; 14(1):86-92.
73. Moe KE, Weiss ML, Epstein AN. Sodium appetite during captopril blockade of endogenous angiotensin II formation. Am J Physiol 1984;247:R356-R365.
74. Weisinger RS, Denton DA, Di Nicolantonio R, McKinley MJ. The effect of captopril or enalaprilic on the Na appetite of Na-deplete rats. Clin Exp Pharmacol Physiol 1988;15:55-65.
75. Thunhorst RL, Fitts DA. Peripheral angiotensin causes salt appetite in rats. Am J Physiol 1994;2267:R171-R177.
76. Falcon JE, Phillips MI, Hoffman WE, Brody MJ. Effects of intraventricular angiotensin II mediated by the sympathetic nervous system. Am J Physiol 1978;235:H392-H397.
77. Severs WB, Daniels-Severs A. Effects of angiotensin on the central nervous system. Pharmacol Rev 1973;25:415-63.
78. Unger T, Becker H, Petty M et al. Differential effects of central angiotensin II and substance P on sympathetic nerve activity in conscious rats. Circ Res 1985;56:563-75.
79. May CN, McAllen RM. Baroreceptor-independent renal nerve inhibition by ICV angiotensin II in conscious sheep. Am J Physiol 1997;273:R560-R567.
80. Bains JS, Ferguson AV. Paraventricular nucleus neurons projecting to the spinal cord receive excitatory input from the subfornical organ. Am J Physiol 1995;268:R625-R633.
81. Bains JS, Potyok A, Ferguson AV. Angiotensin II actions in paraventricular nucleus: functional evidence for a neurotransmitter role in efferents originating in subfornical organ. Brain Res 1992;599:223-9.
82. Casto R, Philips MI. Cardiovascular actions of microinjections of angiotensin II on the brain stem of rats. Am J Physiol 1984;246:R811-R816.
83. Rettig R, Healy DP, Printz MP. Cardiovascular effects of microinjections of angiotensin II into the nucleus tractus solitarii. Brain Res 1986; 364:233-40.
84. Dampney RAL. Functional organisation of central pathways regulating the cardiovascular system. Physiol Rev 1994;74:323-64.
85. Allen AM, Dampney RAL, Mendelsohn FAO. Angiotensin receptor binding and pressor effects in the cat subretrofacial nucleus. Am J Physiol 1988;255:H1011-H1017.
86. Andreatta SH, Averill DB, Santos RAS, Ferrario CM. The ventrolateral medulla: A new site of action of the renin-angiotensin system. Hypertension 1988;11[Suppl I]:I-163-I-166.
87. Sasaki S, Dampney RAL. Tonic cardiovascular effects of angiotensin II in the ventrolateral medulla. Hypertension 1990;15:274-83.
88. Lewis DI, Coote JH. Angiotensin II in the spinal cord of the rat and its sympatho-excitatory effects. Brain Res 1993;614:1-9.
89. Gardner J, Coote JH. Cluster analysis of the effects on renal and adrenal nerve activity of stimulation of the paraventricular nucleus in the rabbit. J Physiol 1996;497:17(Abstract).
90. Allen AM, Mendelsohn FAO, Gieroba ZJ, Blessing WW. Vasopressin release following microinjection of angiotensin II into the caudal ventrolateral medulla in the anaesthetized rabbit. J Neuroendocrinol 1990;2:867-74.
91. Diz DI, Barnes KL, Ferrario CM. Hypotensive actions of microinjections of angiotensin II into the dorsal motor nucleus of the vagus. J Hypertens 1984;2[Suppl 3]:53-6.
92. Casto R, Phillips MI. Angiotensin II attenuates baroreflexes at nucleus tractus solitarius of rats. Am J Physiol 1986;250:R193-R198.
93. Campagnole-Santos MJ, Diz DI, Ferrario CM. Baroreceptor reflex modulation by angiotensin II at the nucleus tractus solitarii. Hypertension 1988; 11 [Suppl I]:I-67-I-171.
94. Paton JFR, Kasparov S. Sensory channel specific modulation in the nucleus of the solitary tract. J Auton Nerv Syst 2000; 80:117-29.
95. Lewis SJ, Allen AM, Verberne AJM, Figdor R, Jarrott B, Mendelsohn FAO. Angiotensin II receptor binding in the rat nucleus tractus solitarii is reduced after unilateral nodose ganglionectomy or vagotomy. Eur J Pharmacol 1986;125:305-7.
96. Diz DI, Barnes KL, Ferrario CM. Contribution of the vagus nerve to angiotensin II binding sites in the canine medulla. Brain Res Bull 1986;17:497-506.
97. Qu L, McQueeney AJ, Barnes KL. Presynaptic or postsynaptic location of receptors for angiotensin II and substance P in the medial solitary tract nucleus. J Neurophysiol 1996;75:2220-8.
98. Fitzsimons JT. Angiotensin stimulation of the central nervous system. Rev Physiol Biochem Pharmacol 1980;87:117-67.
99. O'Neill TP, Brody MJ. Role for the median preoptic nucleus in centrally evoked pressor responses. Am J Physiol 1987;252:R1165-R1172.
100. Buggy J, Fisher AE. Anteroventral third ventricle site of action of angiotensin induced thirst. Pharmacol Biochem Behav 1976;4:651-60.
101. Fregly MJ, Rowland NE. Effect of DuP 753, a non-peptide angiotensin II receptor antagonist, on the drinking responses to acutely administered dipsogenic agents in rats. Proc Soc Exp Biol Med 1992;199:158-64.
102. Rowland NE, Rozelle A, Riley PJ, Fregly MJ. Effect of non-peptide angiotensin receptor antagonists on water and salt intake in rats. Brain Res Bull 1992;29:389-93.
103. Blair-West JR, Denton DA, McKinley MJ, Weisinger RS. Thirst and brain angiotensin in cattle. Am J Physiol 1992;262:R204-R210.
104. Mathai M, Evered MD, McKinley MJ. Intracerebroventricular losartan inhibits post-prandial drinking in sheep. Am J Physiol 1997;272:R1055-R1059.
105. Andersson B, Eriksson L, Fernandez O, Kolmodin C-G, Oltner R. Centrally mediated effects of sodium and angiotensin II on arterial pressure and fluid balance. Acta Physiol Scand 1972;85:398-407.
106. Wilkin LD, Mitchell LD, Ganten D, Johnson AK. The supraoptic nucleus: afferents from areas involved in control of body fluid homeostasis. Neuroscience 1989;28:573-83.
107. Bealer S, Phillips MI, Johnson AK, Schmid PG. Anteroventral third ventricle lesions reduce antiduiretic responses to angiotensin II. Am J Physiol 1979;236:E610-E615.
108. Scholkens BA, Jung W, Rasher W, Dietz R, Ganten D. Intracerebroventricular angiotensin II increases arterial blood pressure in Rhesus Monkeys by stimulation of pituitary hormones and the sympathetic nervous system. Experientia 1982;38:469-73.
109. Sumitomo T, Suda T, Nakano Y, Tozawa F, Yamada M, Demura H. Angiotensin II increases the corticotropin releasing factor messenger ribonucleic acid level in the rat hypothalamus. Endocrinology 1991;128:2248-52.
110. Aguilera G, Young WS, Kiss A, Bathia A. Direct regulation of hypothalmic corticotropin releasing hormone neurons by angiotensin II. Neuroendocrinology 1995;61:437-44.
111. 1) expressing neurons in the hypothalamic paraventricular nucleus. J Neuroendocrinology 2001;13:139-46.
112. Fitzsimons JT. Angiotensin, thirst and sodium appetite. Physiol Rev 1998;78:583-682.
113. Coghlan JP, Considine PJ, Denton DA et al. Sodium appetite in sheep induced by cerebral ventricular infusion of angiotensin: Comparison with sodium deficiency. Science 1981;214:195-7.
114. Galaverna O, Deluca LA, Schulkin J, Yao SZ, Epstein AN. Deficits in NaCl ingestion after damage to the central nucleus of the amygdala in the rat. Brain Res Bull 1992;28:89-98.
115. Unger T, Horst PJ, Bauer M, Demmert G, Rettig R. Natriuretic action of central angiotensin II in conscious rats. Brain Res 1999;486:33-8.
116. Eriksson L, Fyhrquist F. Plasma renin activity following central infusions of and altered CSF sodium concentration in the conscious goat. Acta Physiol Scand 1976;48:209-16.
117. Mathai ML, Evered MD, McKinley MJ. Central losartan blocks natriuretic, vasopressin and pressor responses to central hypertonic NaCl in sheep. Am J Physiol 1998;275:R548-R554.
118. McKinley MJ, Evered M, Mathai M, Coghlan JP. Effects of central losartan on plasma renin and centrally mediated natriuresis. Kidney Int 1994;46:1479-82.
119. Malayan SA, Keil LC, Ramsay DJ, Reid IA. Mechanism of suppression of plasma renin activity by centrally administred angiotensin II. Endocrinology 1979;104:672-5.
120. Weekly LB. Renal renin secretion and norepinephrine secretion rate in response to centrally administered angiotensin II: Role of medial basal forebrain. Clin Exp Hypertension 1992;14:923-45.
121. Sharpe LG, Swanson LW. Drinking induced by injections of angiotensin into forebrain and midbrain sites of the monkey. J Physiol (Lond.) 1974;239:595-622.
122. Lin MT. Effects of angiotensin II on metabolic, respiratory and vasomotor activities as well as body temperature in the rabbit. J Neural Transmission 1980;49:197-204.
123. Shido O, Nagasaka T. Effects of intraventricular angiotensin II on heat balance at various ambient termperatures in rats. Jap J Physiol 1985;35:163-7.
124. Fregly MJ, Rowland NE. Effect of losartan potassium and deoxycorticosterone acetate on tail skin temperature response to acute amdinistration of angiotensin II. Pharmacol Biochem Behav 1992;43:229-33.
125. Melo JC, Graeff FG. Effect of intracerebroventricular bradykinia and related peptides on rabbit operant behaviour. J Pharmacol Exper Ther 1975;193:1-10.
126. Morgan TM, Routtenberg A. Angiotensin injected into the neostriatum after learning disrupts retention performance. Science 1977;196:87-9.
127. Koller M, Krause HP, Hoffmeister F, Ganten D. Endogenous brain angiotensin II disrupts passive avoidance behaviour in rats. Neurosci Lett 1979;14:71-5.
128. DeNoble VJ, DeNoble KF, Spencer KR, Chiu AT, Wong PC, Timmermans BM. Non-peptide angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitor: Effect on a renin-induced deficit of a passive avoidance response in rats. Brain Res 1991;561:230-5.
129. Barnes JM, Barnes NM, Costall B et al. Angiotensin II inhibits cortical cholinergic function: Implications for cognition. J Cardiovasc Pharmacol 1990;16:234-8.
130. Barnes JM, Barnes NM, Costall B et al. Angiotensin II inhibits acetylcholine release from human temporal cortex: Implications for cognition. Brain Res 1990;507:341-3.
131. Costall B, Coughlan J, Horovitz ZP, Kelly ME, Naylor RJ, Tomkins DM. The effects of ACE inhibitors captopril and SQ29852 in rodent tests of cognition. Pharmacol Biochem Behav 1989;33:573-80.