Population pharmacokinetics of fast release oral diclofenac in healthy volunteers: Relation to pharmacodynamics in an experimental pain model

Pharmaceutical Research

Volumn 17, Issue 1, 2000, Pages 77-84

  Lötsch, Jörn ^a,c   Kettenmann, Birgit ^b   Renner, Bertold ^b   Drover, David ^a   Brune, Kay ^b   Geisslinger, Gerd ^c   Kobal, Gerd ^b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c GOETHE UNIVERSITY   (Germany)

Author keywords

Diclofenac tablets; Diclofenac Na effervescent; Double blind four way crossover study; Drug absorption; Pharmacodynamics; Population pharmacokinetics

Indexed keywords

DICLOFENAC;

ADULT; ANALGESIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; COMPARTMENT MODEL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG HALF LIFE; EFFERVESCENT TABLET; ENTERIC COATED TABLET; EVOKED RESPONSE; EXPERIMENTAL MODEL; FEMALE; HUMAN; MALE; NORMAL HUMAN; PAIN; POPULATION RESEARCH; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CROSS-OVER STUDIES; DICLOFENAC; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; PAIN;

EID: 0002309350     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007574710140     Document Type: Article

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