A convenient synthesis of difluoromethyl-substituted pyridines

Synlett

Volumn , Issue 5, 1997, Pages 591-592

  Katsuyama, Isamu ^a   Funabiki, Kazumasa ^a   Matsui, Masaki ^a   Muramatsu, Hiroshige ^a   Shibata, Katsuyoshi ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0002057265     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1997-3232     Document Type: Article

References (13)

1. Coutts, R. T.; Casy, A. F. In Pyridine and its Derivatives, Supplement IV; Abramovitch, R. A. Ed.; Wiley: New York, 1975; p 445.
2. Krogsgaadd-Lassen, P.; Falch, E.; Christensen, V. Drugs Future. 1984, 9, 597.
3. Keys, L. D.; Hamilton, G, A. J. Am. Chem. Soc. 1987, 109, 2156.
4. Filler, R.; Kobayashi, Y. Biomedicinal Aspects of Fluorine Chemistry; Kodansha: Tokyo, 1982.
5. Welch, J. T.; Eswarakrishnan, S. Fluorine in Bioorganic Chemistry, Wiley: New York, 1991.
6. Lee, L. F. Eur. Pat. Appl. EP 133612, 1985; Chem. Abstr. 1986, 104, 19514.
7. Howarth, J. A.; Owton, W. M.; Percy, J. M. J. Chem. Soc., Chem. Commun. 1995, 757.
8. Bègué, J. P.; Bonnet-Delpon, D.; Rock, M. H. Synlett 1995, 659.
9. Shi, G. -Q.; Cao, Z. -Y.; Cai, W. -L. Tetrahedron 1995, 51, 5011.
10. Lee, L. F.; Stikes, G. L.; Molyneaux, J. M.; Sing, Y. L.; Chupp, J. P.; Woodard, S. S. J. Org. Chem., 1990, 55, 2872.
11. Ketones 1 were prepared by using the method described in our previous paper. See Katsuyama, I.; Funabiki, K.; Matsui, M.; Muramatsu, H; Shibata, K. Chem. Lett. 1996, 179.
12. Phosphorus oxychloride/pyridine adsorbed on silica gel was prepared by using the method described in our previous paper. See Katsuyama, I.; Funabiki, K.; Matsui, M.; Muramatsu, H; Shibata, K. Tetrahedron Lett., 1996, 37, 4177.
13. +), 318 (74), 272 (93).