Reactive Oxygen Species and Tendon Problems: Review and Hypothesis

Sports Medicine and Arthroscopy Review

Volumn 8, Issue 1, 2000, Pages 6-16

  Bestwick, Charles S ^a   Maffulli, Nicola ^b  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Antioxidants; Exercise; Oxidative stress; Reactive oxygen; Tendinopathy; Tendinoses

Indexed keywords

EID: 0001958291     PISSN: 10628592     EISSN: None     Source Type: Journal    
DOI: 10.1097/00132585-200008010-00002     Document Type: Review

References (81)

1. Khan KM, Maffulli N. Tendinopathy: an Achilles' heel for athletes and clinicians. Clin J Sports Med 1998;8:151-154.
2. Maffulli N, Khan KM, Puddu G. Overuse tendon conditions: time to change a confusing terminology. Arthroscopy 1998;14:840-843.
3. Järvinen M, Jozsa L, Kannus P, et al. Histopathological findings in chronic tendon disorders. Scand J Med Sci Sports 1997;7:86-95.
4. Waterston SW, Maffulli N, Ewen SW. Subcutaneous rupture of the Achilles tendon: basic science and aspects of clinical practice. Br J Sports Med 1997;31:285-298.
5. Jozsa L, Kannus P. Human Tendons. Champaign, IL: Human Kinetics, 1997:576.
6. Perugia L, Postacchini F, Ippolito E. The Tendons: Biology, Pathology, Clinical Aspects. Milano: Editrice Kurtis, 1986:512.
7. Harms J, Biehl G, von Hobach G. Pathologie de Paratenonitis achillea bei Hochleistungssportlern. Arch Orthop Unfallchir 1977; 88:65-74.
8. Puddu G, Ippolito E, Postacchini F. A classification of Achilles tendon disease. Am J Sports Med 1976;4:145-150.
9. Burry HC, Pool CJ. Central degeneration of the achilles tendon. Rheumatol Rehabil 1973;12:177-181.
10. Merkel KH, Hess H, Kunz M. Insertion tendinopathy in athletes: a light microscopic, histochemical and electron microscopic examination. Pathol Res Pract 1982;173:303-309.
11. Clancy WGJ, Neidhart D, Brand RL. Achilles tendonitis in runners: a report of 5 cases. Am J Sports Med 1976;4:46-57.
12. Williams JG. Achilles tendon lesions in sport. Sports Med 1986; 3:114-135.
13. Denstad TF, Roaas A. Surgical treatment of partial Achilles tendon rupture. Am J Sports Med 1979;7:15-17.
14. Fox JM, Blazina ME, Jobe FW, et al. Degeneration and rupture of the Achilles tendon. Clin Orthop Relat Res 1975;107:221-224.
15. Astrom M, Rausing A. Chronic Achilles tendinopathy: a survey of surgical and histopathologic findings. Clin Orthop 1995;316:151-164.
16. Kvist M, Jozsa L, Jarvinen M, et al. Fine structural alterations in chronic Achilles paratenonitis in athletes. Pathol Res Pract 1985; 180:416-423.
17. McMaster PE. Tendon and muscle ruptures: clinical and experimental studies on the causes and location of suncutaneous ruptures. J Bone Joint Surg 1933;15:705-722.
18. Barfred T. Experimental rupture of the Achilles tendon: comparison of various types of experimental ruptures in rats. Acta Orthop Scand 1971;42:528-543.
19. Barfred T. Kinesiological comments on subcutaneous rupture of the Achilles tendon. Acta Orthop Scand 1971;42:397-405.
20. Josza L, Kvist M, Balint BJ, Reffy A, Jarvinen M, Lehto M, Barzo M. The role of recreational sport activity in Achilles tendon rupture. Am J Sport Med 1989;17:338-343.
21. Gigante A, Specchia N, Rapali S, Ventura A, de Palma L. Fibrillogenesis in tendon healing: an experimental study. Boll Soc Ital Biol Sper 1996;72:203-210.
22. Viidik A. Tendons and ligaments. In: Cooper WD, ed. Extracellular Matrix. Vol. 1: Tissue Function. Hardwood Academic Publishers, 1996:303-327.
23. Chan B, Chan KM, Maffulli N, Webb S, Lee KKH. Effect of basic fibroblast growth factor: an in vitro study of tendon healing. Clin Orthop Relat Res 1997;342:239-247.
24. Banes AJ, Tsuzaki M, Yamamoto J, Fischer T, Brigman B, Brown T, Miller L. Mechanoreception at the cellular level: the detection, interpretation, and diversity of responses to mechanical signals. Biochem Cell Biol 1995;73:349-365.
25. Banes AJ, Tsuzaki M, Hu P, et al. PDGF-BB, IFF-I and mechanical load stimulate DNA synthesis in avian tendon fibroblasts in vitro. J Biomechanics 1995;28:1505-1513.
26. Aizawa T, Kokubun S, Tanaka Y. Apoptosis and proliferation growth plate chondrocytes in rabbits. J Bone Joint Surg 1997;79B: 483-486.
27. Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. Oxford, New York: Oxford Science Publications, Oxford University Press, 1999:1-508.
28. Flowers F, Zimmerman JJ. Reactive oxygen species in the cellular pathophysiology of shock. New Horizons 1998;6:169-180.
29. Sahnoun Z, Jamoussi K, Mounir Zeghal K. Radicaux libres et anti-oxydants: physiologie, pathologie humaine et aspects therapeutics. Therapie 1997;52:251-270.
30. Szabo C. DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite. Free Rad Biol Med 1996;21:855-869.
31. Clanton TL, Zuo L, Klawitter P. Oxidants and skeletal muscle function: physiologic and pathophysiologic implications. Proc Soc Exp Biol Med 1999;222:253-262.
32. Gokturk E, Turgut A, Baycu C, Gunal I, Seber S, Gulbas Z. Oxygen free radicals impair fracture healing in rats. Acta Orthop Scand 1995;66:473-475.
33. Burdon RH, Gill V, Rice-Evans C. Cell proliferation and oxidative stress. Free Rad Res Commun 1989;7:149-159.
34. Chenais B, Andriollo M, Guiraud P, Belhoussine R, Jeannesson P. Oxidative stress involvement in chemically induced differentiation of K562 cells. Free Rad Biol Med 2000;28:18-27.
35. Jabs T. Reactive oxygen intermediates as mediators of programmed cell death in plants and animals. Biochem Pharmacol 1999;57:231-245.
36. Lander MH. An essential role for free radicals and derived species in signal transduction. FASEB J 1997;11:118-124.
37. Gabbita SP, Robinson KA, Stewart CA, Floyd RA, Hensley K. Redox regulatory mechanisms of cellular signal transduction. Arch Biochem Biophys 2000;376:1-13.
38. Kamata H, Hirata H. Redox regulation of cellular signaling. Cell Signal 1999;11:1-14.
39. Schultz-Osthoff K, Baver MK, Vopt M, Wesselborg S. Oxidative stem and signal transduction. Int J Vitam Nutr Res 1997;67:336-342.
40. Morel Y, Barouki R. Repression of gene expression by oxidative stress. Biochem J 1999;342:481-496.
41. Sun Y, Oberley LW. Redox regulation of transcriptional activators. Free Rad Biol Med 1996;21:335-348.
42. Halliwell B. Oxidative stress, nutrition and health: experimental strategies for optimization of nutritional antioxidant intake in humans. Free Rad Res 1996;1:57-74.
43. Wei ZH, Lau BHS. Garlic inhibits free radical generation and augments antioxidant enzyme activity in vascular endothelial cells. Nutr Res 1998;18:61-70.
44. Wei ZH, Peng QL, Lau BHS. Pycnogenol enhances endothelial cell antioxidant defenses. Redox Report 1997;3:219-224.
45. Bestwick CS, Milne L. Effects of β-carotene on antioxidant enzyme activity, intracellular reactive oxygen and membrane integrity within post confluent Caco-2 intestinal cells. Biochim Biophys Acta 2000;1474:47-55.
46. Lowe GM, Booth LA, Young AJ, Billon RF. Lycopene and β-carotene protect against oxidative damage in HT29 cells at low concentrations but rapidly lose this capacity at high doses. Free Rad Res 1999;30:141-151.
47. Muira YH, Tomita I, Watanabe T, Hirayama T, Fukui S. Active oxygen generation by flavonoids. Biol Pharm Bull 1998;21:93-96.
48. Ji LL. Antioxidants and oxidative stress in exercise. PSEBM 2000; 222:283-292.
49. Aruoma IO. Free radical and antioxidant strategies in sports. J Nutr Biochem 1994;5:370-381.
50. Tiidus PM. Radical species in inflammation and overtraining Can J Physiol Pharmacol 1998;76:533-538.
51. Yamada M, Suzuki K, Kudo S, Totsuka M, Simoyama T, Nakaji S, Sugawara K. Effects of exhaustive exercise on human neutrophils in atheletes. Luminescence 2000;15:15-20.
52. Hack V, Strobel G, Rau JP, Weicker H. The effect of maximal exercise on the activity of neutrophil granulocytes in highly trained atheletes in a moderate training period. Eur J Appl Physiol 1992; 65:520-524.
53. Goodship AE, Birch HL, Wilson AM. The pathobiology and repair of tendon and ligament injury. Vet Clin North Am Equine Pract 1994;10:323-348.
54. Meier B, Radeke HH, Selle S, Younes M, Sies H, Resch K, Habermehl GG. Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha. Biochem J 1989;263:539-545.
55. 2 generation in 3T3 L1-cells. Biochem J 1995;307:549-556.
56. Souren JEM, Van Aken H, Van Wij KR. Enhancement of superoxide production against heat shock by HSP27 in fibroblasts. Biochem Biophys Res Commun 1996;227:816-821.
57. Hiran ST, Moulton PJ, Hancock JT. Detection of superoxide and NADPH oxidase in porcine articular chondrocytes. Free Rad Biol Med 1997;23:736-743.
58. Goldman R, Moshonov S, Zor U. Generation of reactive oxygen species in a human keratinocyte cell line: role of calcium. Arch Biochem Biophys 1998;350:10-18.
59. Rosen GM, Pou S, Ramos CL, Cohen MS, Bratigan BE. Free radicals and phagocytic cells. FASEB J 1995;9:200-209.
60. Weitzman A, Gordon LI. Inflammation and cancer: role of phagocyte-generated oxidants in carcinogenesis. J Am Soc Hematol 1990;76:655-663.
61. Weitzman SA, Weitberg AB, Clark EP, Stossel TP. Phagocytes as carcinogens: malignant transformation produced by human neutrophils. Science 1985;227:1231-1233.
62. Kvist M, Josza L, Jarvinen MJ, Kvist H. Chronic achilles paratenonitis in athletes: a histological and histochemical study. Pathology 1987;19:1-11.
63. Yabe N, Matsui H. Ampelopsis brevipedunculata (Vitaceae) extract stimulates collagen synthesis through superoxide generation in the serum free cultures of rat dermal fibroblasts and Ito cells. J Ethnopharmacol 1997;56:67-76.
64. Riedle B, Kerjasckki D. Reactive oxygen species cause direct damage of Engelbreth-Holm-Swarm matrix. Am J Pathol 1997;151: 215-213.
65. Scott JE, Thomlinson AM. The structure of interfibrillar proteoglycan bridges ("shape modules") in extracellular matrix of fibrous connective tissues and their stability in various chemical environments. J Anat 1998;192:391-405.
66. Poli G, Parola M, Oxidative damage and fibrogenesis. Free Rad Biol Med 1997;22:287-305.
67. Cao M, Stefanovic M, Georgescu HI, Fu FH, Evans C. Does nitric oxide help to explain the differential healing capacity of the anterior cruciate, posterior cruciate, and the medical collateral ligaments. Am J Sports Med 2000;28:176-182.
68. Tsuzaki M, Brigman B, Xiao H, Lawrence WT, Van Wyk J, Banes AJ. IGF-I and TGF-β1 drive tendon cell DNA synthesis. Trans Orthop Res Soc 1994;19:18-30.
69. 2 for platelet-derived growth factor signal transduction. Science 1995;270:296-299.
70. Zakeri Z, Bursch W, Tenniswood M, Lockshin RA. Cell death: programmed, apoptosis, necrosis or other. Cell Death Differentiation 1995;2:87-96.
71. Leist M, Nicotera P. The shape of cell death. Biochem Biophys Res Commun 1997;236:1-9.
72. Wang T-S, Kuo C-F, Jan K-Y, Huang H. Arsensite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species. J Cell Physiol 1996;169:256-268.
73. Sandoval M, Ronzio R, Muanza DN, Clark DA, Miller MJS. Peroxynitrite-induced apoptosis in epithelial (T84) and macrophage (RAW 264.7) cell lines: effect of legume-derived polyphenols (phytolens). Nitric Oxide 1997;1:476-438.
74. Briehl MM, Baker AF. Modulation of the antioxidant defense as a factor in apoptosis. Cell Death Differentiation 1996;3:63-70.
75. Sato K, Watanabe S, Yoshizawa T, Hirose M, Murai T, Sato N. Ammonia, hydrogen peroxide, and monochloramine retard gastric epithelial restoration in rabbit cultured cell model. Digest Dis Sci 1999;44:2429-2434.
76. Nishio E, Watanabe Y. The involvement of reactive oxygen species and arachidonic acid in alpha(1)-adrenoceptor-induced smooth muscle cell proliferation and migration. Br J Pharmacol 1997;121:665-670.
77. Fielding RA, Meydant M. Exercise, free radical generation, and aging. Aging Clin Exp Res 1997;9:12-18.
78. Ji LL, Leichtweiss S. Exercise and oxidative stress: sources of free radicals and their impact on antioxidant systems. Age 1997;20:91-106.
79. Davies KJ, Quintanilha TA, Brooks GA, Packer L. Free radicals and tissue damage produced by exercise. Biochem Biophys Res Commun 1982;107:1198-1205.
80. Scotland's Health: A Challenge to Us All - report of a working party to the Chief Medical Officer for Scotland. In: The Scottish Diet. The Scottish Office Home and Health Department, 1993.
81. Murrell GAC, Szabo C, Hannafin JA, Jang D, Dolan MM, Deng X-H, Murrell DF, Warren RF. Modulation of tendon healing by nitric oxide. Inflamm Res 1997;46:19-27.