Multidrug ABC transporters from bacteria to man: an emerging hypothesis for the universality of molecular mechanism and function

Drug Resistance Updates

Volumn 1, Issue 2, 1998, Pages 81-83

  Hrycyna, Christine A ^a   Gottesman, Michael M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001774132     PISSN: 13687646     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1368-7646(98)80019-8     Document Type: Note

References (32)

1. Gottesman M.M., and Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 62 (1993) 385-447
2. Hyde S.C., Emsley P., Hartshorn M.J., et al. Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance, and bacterial transport. Nature 346 (1990) 362-365
3. Cole S.P., Bhardwaj G., Gerlach J.H., et al. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 258 (1992) 1650-1654
4. Riordan J.R., Rommens J.M., Kerem B.-S., et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245 (1989) 1066-1073
5. McGrath J.P., and Varshavsky A. The yeast STE6 gene encodes a homologue of the mammalian multidrug-resistance P-glycoprotein. Nature 340 (1989) 400-404
6. Kuchler K., Sterne R.E., and Thorner J. Saccharamyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells. EMBO J 8 (1989) 3973-3984
7. Allikmets R., Shroyer N.F., Singh N., et al. Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration. Science 277 (1997) 1805-1807
8. Allikmets R., Singh N., Sun H., et al. A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy. Nat Genet 15 (1997) 236-246
9. Kamijo K., Taketani S., Yokota S., et al. The 70-kDa peroxisomal membrane protein is a member of the MDR (P-glycoprotein)-related ATP-binding protein superfamily. J Biol Chem 265 (1990) 4534-4540
10. Gärtner J., Moser H., and Valle D. Mutations in the 70 K peroxisomal membrane protein gene in Zellweger syndrome. Nature Genet 1 (1992) 16-23
11. Gartner J., and Valle D. The 70 kDa peroxisomal membrane protein: an ATP-binding cassette transporter protein involved in peroxisome biogenesis. Semin Cell Biol 4 (1993) 45-52
12. Mosser J., Lutz Y., Stoeckel M.E., et al. The gene responsible for adrenoleukodystrophy encodes a peroxisomal membrane protein. Hum, Mol, Genet 3 (1994) 265-271
13. Lombard-Platet G., Savary S., Sarde C.O., et al. A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern. Proc Natl Acad Sci USA 93 (1996) 1265-1269
14. Monaco J.J., Cho S., and Attaya M. Transport protein genes in the murine MHC: possible implications for antigen processing. Science 250 (1990) 1723-1726
15. Monaco J.J. Major histocompatibility complex-linked transport proteins and antigen processing. Immunol Res 11 (1992) 125-132
16. Shepherd J.C., Schumacher T.N.M., Ashtonrickardt P.G., et al. TAPI-dependent peptide translocation in vitro is ATP dependent and peptide selective. Cell 74 (1993) 577-584
17. Kunst F., Ogasawara N., Moszer I., et al. The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature 390 (1997) 249-256
18. van Veen H.W., Callaghan R., Soceneantu L., et al. A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene. Nature 391 (1998) 291-295
19. van Veen H.W., Venema K., Bolhuis H., et al. Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDRI. Proc Natl Acad Sci USA 93 (1996) 10668-10672
20. Evans G.L., Ni B., Hrycyna C.A., et al. Heterologous expression systems for P-glycoprotein: E coli, yeast, and baculovirus. J Bioenerg Biomembr 27 (1995) 43-52
21. Raviv Y., Pollard H.B., et al. Photosensitized labeling of a functional multidrug transporter in living drug-resistant tumor cells. J Biol Chem 265 (1990) 3975-3980
22. Bolhuis H., van Veen H.W., Molenaar D., et al. Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane. EMBO J 15 (1996) 4239-4245
23. Johnson P.J., Schuck B.L., and Delgadillo M.G. Analysis of a single-domain P-glycoprotein-like gene in the early-diverging protist Trichomonas vaginalis. Mol Biochem Parasitol 66 (1994) 127-137
24. Shani N., and Valle D.A. Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters. Proc Natl Acad Sci USA 93 (1996) 11901-11906
25. Tearle R.G., Belote J.M., McKeown M., et al. Cloning and characterization of the scarlet gene of Drosophila melanogaster. Genetics 122 (1989) 595-606
26. Pepling M., and Mount S.M. Sequence of a cDNA from the Drosophila melanogaster white gene. Nucleic Acids Res 18 (1990) 1633
27. O'Hare K., Murphy C., Levis R., and Rubin G.M. DNA sequence of the white locus of Drosophila melanogaster. J Mol Biol 180 (1984) 437-455
28. Dreesen T.D., Johnson D.H., and Henikoff S. The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes. Mol Cell Biol 8 (1988) 5206-5215
29. Higgins C.F. ABC transporters: from microorganisms to man. Annu Rev Cell Biol 8 (1992) 67-113
30. Rosenberg M.F., Callaghan R., Ford R.C., and Higgins C.F. Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis. J Biol Chem 272 (1997) 10685-10694
31. Loo T.W., and Clarke D.M. The minimum functional unit of human P-glycoprotein appears to be a monomer. J Biol Chem 271 (1996) 27488-27492
32. Gottesman M.M., Hrycyna C.A., Schoenlein P.V., et al. Genetic analysis of the multidrug transporter. Annu Rev Genet 29 (1995) 607-649