Studies toward the Asymmetric Synthesis of α-Amino Phosphonic Acids via the Addition of Phosphites to Enantiopure Sulfinimines

Journal of Organic Chemistry

Volumn 62, Issue 22, 1997, Pages 7532-7533

  Lefebvre, Isabelle M ^a   Evans Jr , Slayton A ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001475118     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo971394o     Document Type: Article

References (29)

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29. 18a indicates that the planar inversion pathway has preference over the rotational option. We speculate that the N-sulfmimines from ketones have higher ground-state energies than N-sulfmimines derived from aldehydes. Therefore, it seems reasonable that the E- to Z-activation energies would be higher for the latter, assuming similar transition state energies.