2-(4-Nitrophenyl)ethyl Methylenebis(phosphonate): A Versatile Reagent for the Synthesis of Nucleoside 5′-Methylenebis(phosphonate)s

Journal of Organic Chemistry

Volumn 63, Issue 6, 1998, Pages 1906-1909

  Lesiak, Krystyna ^a   Watanabe, Kyoichi A ^a   George, Jay ^a   Pankiewicz, Krzysztof W ^a  

^a Division of Medicinal Chemistry   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001606147     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo971859a     Document Type: Article

References (10)

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2. Pankiewicz, K. W.; Lesiak, K.; Zatorski, A.; Goldstein, B. M.; Carr, S. F.; Sochacki, M.; Majumdar, A.; Seidman, M.; Watanabe, K. A. J. Med. Chem. 1997, 40, 1287.
3. Yanachkov, I.; Wright, G. E. Nucleosides Nucleotides 1994, 13, 339 and references herein.
4. Davisson, V. J.; Davis, D. R.; Dixit, V. M.; Poulter, C. D. J. Org. Chem. 1987, 52, 1794.
5. Reist, E.; Hart, P. A.; Goodman, L.; Baker, B. R. J. Org. Chem. 1961, 26, 2538.
6. Kurihara, T.; Nakaijma, Y.; Mitsunobu, O. Tetrahedron Lett. 1976, 17, 2455.
7. Saady, M.; Lebau, L.; Mioskowski, C. Tetrahedron Lett. 1995, 36, 2239.
8. Saady, M.; Lebau, L.; Mioskowski, C. J. Org. Chem. 1995, 60, 2946.
9. Maier, L. Helv. Chim. Acta 1965, 48, 133.
10. 2-isobutyrylguanosine by acetylation with acetic anhydride in pyridine followed by removal of the dimethoxytrityl group by treatment with 80% acetic acid.