Prepregnancy genetic testing for age-related aneuploidies by polar body analysis

Genetic Testing

Volumn 1, Issue 4, 1998, Pages 231-235

  Verlinsky, Y ^a   Cieslak, J ^a   Ivakhnenko, V ^a   Evsikov, S ^a   Wolf, G ^a   White, M ^a   Lifchez, A ^a   Kaplan, B ^a   Moise, J ^a   Valle, J ^a   Ginsberg, N ^a   Strom, C ^a   Kuliev, A ^a  

^a REPRODUCTIVE GENETICS INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; BLASTOCYST; CYTOLOGY; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC SCREENING; HUMAN; MATERNAL AGE; MATERNAL CARE; MEIOSIS; NEWBORN; OOCYTE; PREGNANCY; PREGNANCY OUTCOME; REVIEW;

ANEUPLOIDY; BLASTOCYST; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; GENETIC SCREENING; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT, NEWBORN; MATERNAL AGE; MEIOSIS; OOCYTES; PRECONCEPTION CARE; PREGNANCY; PREGNANCY OUTCOME;

EID: 0001567555     PISSN: 10906576     EISSN: None     Source Type: Journal    
DOI: 10.1089/gte.1997.1.231     Document Type: Article

References (13)

1. BATTAGLIA, D.E., GOODWIN, P., KLEIN, N.A., and SOULES, M.R. (1996). Influence of maternal age on meiotic spindle assembly in oocytes from naturally cycling women. Hum. Reprod. 11, 2217-2222.
2. DYBAN, A., DE SUTTER, P., and VERLINSKY, Y. (1993). Okadaic acid induces premature chromosome condensation reflecting the cell cycle progression in one-cell stage mouse embryos. Mol. Reprod. Devel. 34, 402-415.
3. DYBAN, A., FREDINE, M., SEVEROVA, E., IVAKHNENKO, V., and VERLINSKY, Y. (1996). Detection of aneuploidy in human oocytes and corresponding first polar bodies by FISH. J. Assist. Reprod. Genet. 13, 73-78.
4. MUNNE, S., DAILEY, T., SULTAN, K.M., GRIFO, J., and COHEN, J. (1995). The use of first polar bodies for preimplantation diagnosis of aneuploidy. Hum. Reprod. 10, 1014.
5. VERLINSKY, Y., and KULIEV, A. (eds.). (1994). Preimplantation diagnosis of genetic diseases: A new technique for assisted reproduction. (Wiley Liss, New York).
6. VERLINSKY, Y., GINSBERG, N., LIFCHEZ, A., VALLE, J., MOISE, J., and STROM, C.M. (1990). Analysis of the first polar body: Preconception genetic diagnosis. Hum. Reprod. 5, 826-829.
7. VERLINSKY, Y., RECHITSKY, S., EVSIKOV, S., WHITE, M., CIESLAK, J., LIFCHEZ, A., VALLE, J., MOISE, J., and STROM, C. (1992). Preconception and preimplantation diagnosis for cystic fibrosis. Prenat. Diagn. 12, 103-110.
8. VERLINSKY, Y., DOZORTSEV, D., and EVSIKOV, S. (1994). Visualization and cytogenetic analysis of second polar body chromosomes following its fusion with one-cell mouse embryo. J. Assist. Reprod. Genet. 11, 123-131.
9. VERLINSKY, Y., CIESLAK, J., FREIDINE, M., IVAKHENKO, V., WOLF, G., KOVALINSKAYA, L., WHITE, M., LIFCHEZ, A., KAPLAN, B., MOISE, J., VALLE, J., GINSBERG, N., STROM, C., and KULIEV, A. (1995). Pregnancies following pre-conception diagnosis of common aneuploidies by fluorescent in-situ hybridization. Hum. Reprod. 10, 1923-1927.
10. VERLINSKY, Y., CIESLAK, J., IVAKHNENKO, V., LIFCHEZ, A., STROM, C., and KULIEV, A. (1996a). Birth of healthy children after preimplantation diagnosis of common aneuploidies by polar body fluorescent in-situ hybridization. Fertil. Steril. 66, 126-129.
11. VERLINSKY, Y., CIESLAK, J., FREIDINE, M., IVAKHENKO, V., WOLF, G., KOVALINSKAYA, L., WHITE, M., LIFCHEZ, A., KAPLAN, B., MOISE, J., VALLE, J., GINSBERG, N., STROM, C., and KULIEV, A. (1996b). Polar body diagnosis of common aneuploidies by fluorescent in-situ hybridization. J. Assist. Reprod. Genet. 13, 157-162.
12. VERLINSKY, Y., RECHITSKY, S., CIESLAK, J., IVAKHENKO, V., WOLF, G., LIFCHEZ, A., KAPLAN, B., MOI, J., VALLE, J., WHITE, M., GINSBERG, N., STROM, C., and KULIEV, A. (1997). Preimplantation diagnosis of single gene disorders by Two-Step oocyte genetic analysis using first and second polar body. Biochem. Mol. Med. 62, 182-187.
13. VERLINSKY, Y., CIESLAK, J., IVAKHNENKO, V., EVSIKOV, S., WOLF, G., WHITE, M., LIFCHEZ, A., KAPLAN, B., MOISE, J., VALLE, J., GINSBERG, N., STROM, C., and KULIEV, A. (1998). Preimplantation diagnosis of common aneuploidies by the first and second polar body FISH analysis. J. Assist. Reprod. Genet. 15, 284-288.