Protein kinase inhibitors for the treatment of cancer

Drug Discovery Today

Volumn 1, Issue 8, 1996, Pages 325-330

  Patrick, Denis R ^a   Heimbrook, David C ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001128759     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/1359-6446(96)10030-1     Document Type: Review

References (64)

1. Hanks, S.K. and Hunter, T. (1995) FASEB J. 9, 576-596
2. Borg, A. et al. (1990) Cancer Res. 50, 4332-4337
3. Schonborn, I. et al. (1994) Breast Cancer Res. Treat. 29, 287-295
4. Toi, M. et al. (1991) Eur. J. Cancer 27, 977-980
5. Sainsbury, J.R.C et al. (1987) Lancet i, 1398-1402
6. Maguire, H.C.J. et al. (1992) Pathobiology 60, 117-121
7. Scheccer, A.L. et al. (1984) Nature 312, 513-516
8. Minke, J.M.H.M. et al. (1991) Cancer Res. 51, 4028-4037
9. Santon, J.B. et al. (1986) Cancer Res. 46, 4701-4705
10. Filmus, J. et al. (1987) Mol. Cell. Biol. 7, 251-257
11. Ozawa, S. et al. (1987) Int. J. Cancer 40, 706-710
12. Kumar, R., Shepard, H.M. and Mendelsohn, J. (1991) Mol. Cell. Biol. 11, 979-986
13. Colomer, R. et al. (1994) Br. J. Cancer 70, 819-825
14. Levitzki, A. and Gazit, A. (1995) Science 267, 1782-1788
15. Burke, T.R. (1992) Drugs Future 17, 119-131
16. Akiyama, T. et al. (1987) J. Biol. Chem. 262, 5592-5595
17. Graziani, Y. et al. (1981) Biochim. Biophys. Acta 714, 415-421
18. Umezawa, H. et al. (1986) J. Antibiot. (Tokyo) 39, 170-173
19. Posner, I. et al. (1994) Mol. PharmacoL 45, 673-683
20. Yaish, P. et al. (1988) Science 242, 933-935
21. Yoneda, T. et al. (1991) Cancer Res. 51, 4430-4435
22. Trinks, U. et al. (1994) J. Med. Chem. 37, 1015-1027
23. Buchdunger, E. et al. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 2334-2338
24. Fry, D.W. et al. (1994) Science 265, 1093-1095
25. Bridges, A.J. et al. (1995) Proc. Am. Assoc. Cancer Res. 435
26. Blobe, G.C., Obeid, L.M. and Hannum, Y.A. (1994) Cancer Metastasis Rev. 13, 411-131
27. Dekker, L.V. and Parker, P.J. (1994) Trends Biochem. Sci. 19, 73-77
28. Wilkinson, S.E. and Hallam. T.J. (1994) Trends Pharmacol. Sci. 15, 73-77
29. O'Brian, C.A. et al. (1989) Cancer Res. 49, 3215-3217
30. O'Brian, C.A. et al. (1985) Cancer Res. 45, 2462-2465
31. Guillem, J.G. et al. (1987) Cancer Res. 47, 2036-2039
32. Phan, S-C. et al. (1991) Cancer Res. 51, 1571-1573
33. Choi, P.M., Tchou-Wong, K-M. and Weinstein, I.B. (1990) Mol. Cell. Biol. 10, 4650-4657
34. Ahmad, S. and Glazer, R.I. (1993) Mol. Pharmacol. 43, 858-862
35. Dow, R.L. (1994) Curr. Med. Chem. 1, 192-203
36. Harris, W. et al. (1993) Drug Future 18, 727-735
37. House, C. and Kemp, B.E. (1987) Science 238, 1726-1728
38. Hidaka, H. et al. (1984) Biochemistry 23, 5036-5041
39. Tamaoki, T. et al. (1986) Biochim. Biophys. Res. Commun. 135, 397-402
40. Bit, R.A. et al. (1993) J. Med. Chem. 36, 21-29
41. Martiny-Baron, G. et al. (1993) J. Biol. Chem. 268, 9194-9197
42. Rapp, U.R. et al (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 4218-4222
43. Storm, S.M. et al. (1990) Crit. Rev. Oncogenesis 2, 1-8
44. Miwa, W. et al. (1994) Biol. Chem. Hoppe-Seyler (1994) 375, 705-709
45. Warne, P.H., Viciana, P.R. and Downward, J. (1993) Nature 364, 352-355
46. Zhang, X. et al. (1993) Nature 364, 308-355
47. Kolch, W. et al. (1991) Nature 349, 426-428
48. Cowley, S. et al. (1994) Cell 77, 841-852
49. Kizaka-Kondoh, S. et al. (1992) Mol. Cell. BioL 12, 5078-5086
50. Heidecker, G. et al. (1990) Mol. Cell. Biol. 10, 2503-2512
51. Force, T. et al. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 1270-1274
52. Seger, R. et al. (1992) J. Biol. Chem. 267, 14373-14381
53. Alessi, D.R. et al. (1995) J. Biol. Chem. 270, 27489-27494
54. Dudley, D.T. et al. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7686-7689
55. Pang, L. et al. (1995) J. Biol Chem. 270, 13585-13588
56. Ihle, J.N. (1996) Cell 84, 331-334
57. Taniguchi, T. (1995) Science 268, 251-255
58. Meydan, N. et al. (1996) Nature 379, 645-648
59. Heisterkamp, N. et al. (1983) Nature 306, 239-242
60. Morgan, D.O. (1995) Nature 374, 131-134
61. Jiang, W. (1992) Cancer Res. 52, 2980-2983
62. Keyomarsi, K. and Pardee, A.B. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 1112-1116
63. Seto, M. et al. (1992) Oncogene 7, 1401-1406
64. Kamb, A. et al. (1994) Science 264, 436-440