Structural modifications and biological evaluation of 3-isoxazolylvinylcephalosporins

Tetrahedron

Volumn 56, Issue 31, 2000, Pages 5657-5665

  Pae, Ae Nim ^a   Lee, Jie Eun ^a   Kim, Bo Hyung ^a   Cha, Joo Hwan ^a   Kim, Hea Yeon ^a   Cho, Yong Seo ^a   Choi, Kyung Il ^a   Koh, Hun Yeong ^a   Lee, Eun ^b   Kim, Je Hak ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Antibacterials; Cephalosporins; Isoxazoles; Thiazoles

Indexed keywords

CEPHALOSPORIN DERIVATIVE; ISOTHIAZOLE DERIVATIVE; ISOXAZOLE DERIVATIVE; THIADIAZOLE DERIVATIVE; VINYL DERIVATIVE;

CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CONFERENCE PAPER; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

EID: 0001033677     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(00)00415-4     Document Type: Conference Paper

References (15)

1. (a) Choi, K. I.; Cha, J. H.; Pae, A. N.; Cho, Y. S.; Kang, H. Y.; Koh, H. Y.; Chang, M. H. J. Antibiot. 1995, 48, 1371.
2. (b) Choi, K. I.; Cha, J. H.; Pae, A. N.; Cho, Y. S.; Kang, H. Y.; Koh, H. Y.; Chang, M. H. J Antibiot. 1995, 48, 1375.
3. (c) Choi, K. I.; Cha, J. H.; Pae, A. N.; Cho, Y. S.; Kang, H. Y.; Koh, H. Y.; Chang, M. H. J. Antibiot. 1997, 50, 279.
4. (d) Choi, K. I.; Cha, J. H.; Pae, A. N.; Cho, Y. S.; Kang, H. Y.; Chang, M. H.; Park, S. H.; Park, S. Y.; Kim, D. Y.; Jeong, D. Y.; Kim, Y. H.; Kong, J. Y.; Koh, H. Y. J. Antibiot. 1998, 51, 1122.
5. (e) Choi, K. I.; Cha, J. H.; Pae, A. N.; Cho, Y. S.; Kim, Y. S.; Chang, M. H.; Koh, H. Y. J. Antibiot. 1998, 51, 1117.
6. (f) Choi, K. I. Drugs Future 1999, 24 (3), 287.
7. Glinka, T.; Cho, I.; Zhang, Z.; Price, M.; Case, L.; Crase, J.; Frith, R.; Liu, N.; Ludwikow, M.; Rea, D.; Chamberland, S.; Lee, V.; Hecker, S. Abstract No. F176, 37th Intresci. Antimicrob. Agents Chemother. Toronto, Ontario, Sept. 28, 1997.
8. (a) Taylor, E. C.; Ray P. S. J. Org. Chem. 1991, 56, 1812.
9. (b) Chiarino, D.; Napoletano, M.; Sala, A. Synth. Commun. 1988, 18, 1171.
10. (a) Woodward, R. B.; Reed, W. A. J. Am. Chem. Soc. 1943, 65, 1569.
11. (b) Lykkeberg, J.; Krogsgaard-Larsen P. Acta Chem. Scand. B 1976, 30 (8), 781.
12. (c) Matzen, L.; Engesgaard A.; Ebert B.; Didriken, M.; Frolund, B.; Krogsgaard-Larsen, P.; Jaroszewski, J. W. J. Med. Chem. 1997, 40 (4), 520.
13. (d) Howe R. K.; Gruner, T. A.; Carter, L. G.; Franz, J. E. J. Heterocycl. Chem. 1978, 15, 1001.
14. (e) Kobori T.; Fujita, M.; Hiyama, T.; Kondo, Kiyosi. Synlett 1992, 95.
15. Leitner F., Misiek M., Pursiano T.A., Buck R.E., Chisholm D.R., Deregis R.G., Tsai Y.H., Price K.E. Antimicrob. Agents Chemother. 10:1976;426.