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Volumn 2, Issue 4, 1996, Pages 184-193

An approach to the radiosensitization of human tumors

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; RADIOSENSITIZING AGENT;

EID: 0001002341     PISSN: 10814442     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (30)

References (85)
  • 1
    • 0027690015 scopus 로고
    • New approaches to cell kinetics in human tumors
    • Ritter MA. New approaches to cell kinetics in human tumors. Curr Prob Cancer 1993, 27:325-368.
    • (1993) Curr Prob Cancer , vol.27 , pp. 325-368
    • Ritter, M.A.1
  • 2
    • 0026763110 scopus 로고
    • Local control and patient survival
    • Suit HD. Local control and patient survival. Int J Radiat Oncol Biol Phys 1992; 23:653-660.
    • (1992) Int J Radiat Oncol Biol Phys , vol.23 , pp. 653-660
    • Suit, H.D.1
  • 3
    • 0025719447 scopus 로고
    • Rapid repopulation in radiotherapy: A debate on mechanism. The phantom of tumor treatment-continually rapid proliferation unmasked
    • Fowler JF. Rapid repopulation in radiotherapy: a debate on mechanism. The phantom of tumor treatment-continually rapid proliferation unmasked. Radiother Oncol 1991; 22:156-158.
    • (1991) Radiother Oncol , vol.22 , pp. 156-158
    • Fowler, J.F.1
  • 4
    • 0022197104 scopus 로고
    • A method to measure the duration of DNA synthesis and the potential doubling time from a single sample
    • Begg AC, McNally NJ, Shrieve DC et al. A method to measure the duration of DNA synthesis and the potential doubling time from a single sample. Cytometry 1985; 6:620-626.
    • (1985) Cytometry , vol.6 , pp. 620-626
    • Begg, A.C.1    McNally, N.J.2    Shrieve, D.C.3
  • 5
    • 0026692123 scopus 로고
    • Single biopsy, tumor kinetic analyses: A comparison of methods and an extension to shorter sampling intervals
    • Ritter MA, Fowler JF, Kim Y et al. Single biopsy, tumor kinetic analyses: a comparison of methods and an extension to shorter sampling intervals. Int J Radiat Oncol Biol Phys 1992; 23:811-820.
    • (1992) Int J Radiat Oncol Biol Phys , vol.23 , pp. 811-820
    • Ritter, M.A.1    Fowler, J.F.2    Kim, Y.3
  • 6
    • 0028903082 scopus 로고
    • Advances in radiation therapy for head and neck cancer
    • Harari PM, Kinsella TJ. Advances in radiation therapy for head and neck cancer. Curr Opinion Oncol 1995; 7:248-254.
    • (1995) Curr Opinion Oncol , vol.7 , pp. 248-254
    • Harari, P.M.1    Kinsella, T.J.2
  • 7
    • 0028307190 scopus 로고
    • The molecular basis for cell cycle delays following ionizing radiation
    • Maity A, McKenna WG, Muschel RJ. The molecular basis for cell cycle delays following ionizing radiation. Radiat Oncol 1994; 31:143.
    • (1994) Radiat Oncol , vol.31 , pp. 143
    • Maity, A.1    McKenna, W.G.2    Muschel, R.J.3
  • 8
    • 1842397342 scopus 로고
    • Nuclear posttranslational processing of thymidine kinase mRNA at the onset of DNA synthesis
    • Gudas J, Knight GB, Pardee AB. Nuclear posttranslational processing of thymidine kinase mRNA at the onset of DNA synthesis. Proc Natl Acad Sci USA 1988; 85:4705-4709.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4705-4709
    • Gudas, J.1    Knight, G.B.2    Pardee, A.B.3
  • 9
    • 0030044995 scopus 로고    scopus 로고
    • Overexpression of thymidine kinase mRNA eliminates cell cycle regulation of thymidine kinase enzyme activity
    • Mikulits W, Hengstschlager M, Sauer T et al. Overexpression of thymidine kinase mRNA eliminates cell cycle regulation of thymidine kinase enzyme activity. J Biol Chem 1996; 271:853-860.
    • (1996) J Biol Chem , vol.271 , pp. 853-860
    • Mikulits, W.1    Hengstschlager, M.2    Sauer, T.3
  • 10
    • 0019983556 scopus 로고
    • Activities of various enzymes of pyrimidine nucleotides and DNA synthesis in normal and neoplastic human tissues
    • Maehara Y, Nakamura H, Nakane Y et al. Activities of various enzymes of pyrimidine nucleotides and DNA synthesis in normal and neoplastic human tissues. Gann 1982; 73:289-298.
    • (1982) Gann , vol.73 , pp. 289-298
    • Maehara, Y.1    Nakamura, H.2    Nakane, Y.3
  • 11
    • 0027306169 scopus 로고
    • Isolation of x-ray-inducible transcripts from radioresistant human melanoma cells
    • Boothman DA, Meyers M, Lee SW. Isolation of x-ray-inducible transcripts from radioresistant human melanoma cells. Proc Natl Acad Sci USA 1993; 90:7200-7204.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7200-7204
    • Boothman, D.A.1    Meyers, M.2    Lee, S.W.3
  • 12
    • 0027939874 scopus 로고
    • Enhanced expression of thymidine kinase in human cells following ionizing radiation
    • Boothman DA, Davis TW, Sahijdak WM. Enhanced expression of thymidine kinase in human cells following ionizing radiation. Int J Radiat Oncol Biol Phys 1994; 30:391-398.
    • (1994) Int J Radiat Oncol Biol Phys , vol.30 , pp. 391-398
    • Boothman, D.A.1    Davis, T.W.2    Sahijdak, W.M.3
  • 13
    • 0027988163 scopus 로고
    • Expression of thymidine kinase is essential to low dose rate radiation resistance of rat glioma cells
    • Al-Nabulsi IY, Takamiya Y, Voloshin A et al. Expression of thymidine kinase is essential to low dose rate radiation resistance of rat glioma cells. Cancer Res 1994; 54:5614-5617.
    • (1994) Cancer Res , vol.54 , pp. 5614-5617
    • Al-Nabulsi, I.Y.1    Takamiya, Y.2    Voloshin, A.3
  • 14
    • 0021960757 scopus 로고
    • Regulation of thymidylate synthase enzyme synthesis in 5-fluorodeoxyuridine-resistant mouse fibroblasts during the transition from the resting to growing state
    • Jenh C-H, Rao LG, Johnson EF. Regulation of thymidylate synthase enzyme synthesis in 5-fluorodeoxyuridine-resistant mouse fibroblasts during the transition from the resting to growing state. J Cell Physio 1985; 122:149-154.
    • (1985) J Cell Physio , vol.122 , pp. 149-154
    • Jenh, C.-H.1    Rao, L.G.2    Johnson, E.F.3
  • 15
    • 0029021602 scopus 로고
    • Increased thymidylate synthase protein levels are principally associated with proliferation but not cell cycle phase in asynchronous human cancer cells
    • Pestalozzi BC, McGinn CJ, Kinsella TJ et al. Increased thymidylate synthase protein levels are principally associated with proliferation but not cell cycle phase in asynchronous human cancer cells. Br J Cancer 1995; 71:1151-1157.
    • (1995) Br J Cancer , vol.71 , pp. 1151-1157
    • Pestalozzi, B.C.1    McGinn, C.J.2    Kinsella, T.J.3
  • 16
    • 0022473119 scopus 로고
    • Cell-cycle directed regulation of thymidylate synthase messenger RNA in human diploid fibroblasts stimulated to proliferate
    • Ayusawa D, Shimizu K, Koyama H et al. Cell-cycle directed regulation of thymidylate synthase messenger RNA in human diploid fibroblasts stimulated to proliferate. J Mol Biol 1986; 190:556-567.
    • (1986) J Mol Biol , vol.190 , pp. 556-567
    • Ayusawa, D.1    Shimizu, K.2    Koyama, H.3
  • 17
    • 0025990937 scopus 로고
    • Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase
    • Chu E, Koeller DM, Casey JL et al. Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase. Proc Natl Acad Sci USA 1991; 88:8977-8981.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8977-8981
    • Chu, E.1    Koeller, D.M.2    Casey, J.L.3
  • 18
    • 0027531524 scopus 로고
    • Identification of an RNA binding site for human thymidylate synthase
    • Chu E, Voeller D, Koeller DM et al. Identification of an RNA binding site for human thymidylate synthase. Proc Natl Acad Sci USA 1993; 90:517-521.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 517-521
    • Chu, E.1    Voeller, D.2    Koeller, D.M.3
  • 19
    • 0009736754 scopus 로고
    • Thymidylate synthase regulates the translation of p53 mRNA
    • Chu E, Copur S, Jones KL et al. Thymidylate synthase regulates the translation of p53 mRNA. Proc Amer Assoc Cancer Res 1995; 36:563.
    • (1995) Proc Amer Assoc Cancer Res , vol.36 , pp. 563
    • Chu, E.1    Copur, S.2    Jones, K.L.3
  • 20
    • 0027416220 scopus 로고
    • Regulation of thymidylate synthase in human colon cancer cells treated with 5-fluorouracil and interferon-gamma
    • Chu E, Koeller DM, Johnston PG et al. Regulation of thymidylate synthase in human colon cancer cells treated with 5-fluorouracil and interferon-gamma. Mol Pharmacol 1993; 43:527-533.
    • (1993) Mol Pharmacol , vol.43 , pp. 527-533
    • Chu, E.1    Koeller, D.M.2    Johnston, P.G.3
  • 21
    • 0028151449 scopus 로고
    • The role of thymidylate synthase expression in prognosis and outcome to adjuvant chemotherapy in patients with rectal cancer
    • Johnston PG, Fisher ER, Rockette HE et al. The role of thymidylate synthase expression in prognosis and outcome to adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 1994; 12:2640-2647.
    • (1994) J Clin Oncol , vol.12 , pp. 2640-2647
    • Johnston, P.G.1    Fisher, E.R.2    Rockette, H.E.3
  • 22
    • 0001849087 scopus 로고
    • Thymidylate synthase protein expression: Association with response to neoadjuvant chemotherapy and resection for locally advanced gastric and gastroesophageal adenocarcinoma
    • Alexander HR, Grem JL, Hamilton JR et al. Thymidylate synthase protein expression: association with response to neoadjuvant chemotherapy and resection for locally advanced gastric and gastroesophageal adenocarcinoma. Cancer J Sci Am 1995; 1:49-54.
    • (1995) Cancer J Sci Am , vol.1 , pp. 49-54
    • Alexander, H.R.1    Grem, J.L.2    Hamilton, J.R.3
  • 23
    • 0026653689 scopus 로고
    • Radiosensitization by fluorodeoxyuridine: Effects on thymidylate synthase inhibition and cell synchronization
    • Miller EM, Kinsella TJ. Radiosensitization by fluorodeoxyuridine: effects on thymidylate synthase inhibition and cell synchronization. Cancer Res 1992; 52:1687-1694.
    • (1992) Cancer Res , vol.52 , pp. 1687-1694
    • Miller, E.M.1    Kinsella, T.J.2
  • 24
    • 0027605113 scopus 로고
    • DNA damage and cell cycle regulation of ribonucleotide reductase
    • Elledge SJ, Zhou Z, Allen JB, Navas TA DNA damage and cell cycle regulation of ribonucleotide reductase. Bioessays 1993; 15:333-339.
    • (1993) Bioessays , vol.15 , pp. 333-339
    • Elledge, S.J.1    Zhou, Z.2    Allen, J.B.3    Navas, T.A.4
  • 25
    • 0027177564 scopus 로고
    • From RNA to DNA, why so many ribonucleotide reductases?
    • Reichard P. From RNA to DNA, why so many ribonucleotide reductases? Science 1993; 260:1773-1777.
    • (1993) Science , vol.260 , pp. 1773-1777
    • Reichard, P.1
  • 26
    • 0343674388 scopus 로고    scopus 로고
    • Correlation of overexpression of ribonucleotide reductase and radioresistance in a human head and neck squamous cell cancer model
    • Kunugi KA, Sharma R, Sosnay P et al. Correlation of overexpression of ribonucleotide reductase and radioresistance in a human head and neck squamous cell cancer model. Proc Amer Assoc Cancer Res 1996; 37:609.
    • (1996) Proc Amer Assoc Cancer Res , vol.37 , pp. 609
    • Kunugi, K.A.1    Sharma, R.2    Sosnay, P.3
  • 27
    • 0014253355 scopus 로고
    • The combined effect of hydroxyurea and x-rays on Chinese hamster cells in vitro
    • Sinclair WK. The combined effect of hydroxyurea and x-rays on Chinese hamster cells in vitro. Cancer Res 1968; 28:198-206.
    • (1968) Cancer Res , vol.28 , pp. 198-206
    • Sinclair, W.K.1
  • 28
    • 0022211007 scopus 로고
    • Inhibition of DNA excision repair and the repair of x-ray-induced DNA damage by cytosine arabinoside and hydroxyurea
    • Fram RJ, Kufe DW. Inhibition of DNA excision repair and the repair of x-ray-induced DNA damage by cytosine arabinoside and hydroxyurea. Pharmacol Ther 1985; 31:165-176.
    • (1985) Pharmacol Ther , vol.31 , pp. 165-176
    • Fram, R.J.1    Kufe, D.W.2
  • 29
    • 0029025552 scopus 로고
    • The interaction of hydroxyurea and iododeoxyuridine on the radiosensitivity of human bladder cancer cells
    • Kuo M-L, Kunugi KA, Lindstrom MJ, Kinsella TJ. The interaction of hydroxyurea and iododeoxyuridine on the radiosensitivity of human bladder cancer cells. Cancer Res 1995; 55:2800-2805.
    • (1995) Cancer Res , vol.55 , pp. 2800-2805
    • Kuo, M.-L.1    Kunugi, K.A.2    Lindstrom, M.J.3    Kinsella, T.J.4
  • 30
    • 2842610732 scopus 로고    scopus 로고
    • The interaction of hydroxyurea and ionizing radiation in human cervical carcinoma cells: A mechanistic study
    • in press
    • Kuo M-L, Kunugi KA, Lindstrom MJ, Kinsella TJ. The interaction of hydroxyurea and ionizing radiation in human cervical carcinoma cells: a mechanistic study. Cancer Res 1996; in press.
    • (1996) Cancer Res
    • Kuo, M.-L.1    Kunugi, K.A.2    Lindstrom, M.J.3    Kinsella, T.J.4
  • 31
    • 0019441168 scopus 로고
    • Hydroxyurea revisited: A decade of clinical effects studies
    • Sinclair WK. Hydroxyurea revisited: a decade of clinical effects studies. Int J Radiat Oncol Biol Phys 1981; 7:631-637.
    • (1981) Int J Radiat Oncol Biol Phys , vol.7 , pp. 631-637
    • Sinclair, W.K.1
  • 32
    • 0023234589 scopus 로고
    • Hydroxyurea plus pelvic radiation versus placebo plus pelvic radiation in surgically staged stage IIIB cervical cancer
    • Piver MS, Vongtama V, Emrich LJ. Hydroxyurea plus pelvic radiation versus placebo plus pelvic radiation in surgically staged stage IIIB cervical cancer. J Surg Oncol 1987; 35:129-144.
    • (1987) J Surg Oncol , vol.35 , pp. 129-144
    • Piver, M.S.1    Vongtama, V.2    Emrich, L.J.3
  • 33
    • 0024376548 scopus 로고
    • Hydroxyurea plus pelvic irradiation versus placebo plus pelvic irradiation in nonsurgically staged stage IIIB cervical cancer
    • Piver MS, Khalil M, Emrich LJ. Hydroxyurea plus pelvic irradiation versus placebo plus pelvic irradiation in nonsurgically staged stage IIIB cervical cancer. J Surg Oncol 1989; 42:120-125.
    • (1989) J Surg Oncol , vol.42 , pp. 120-125
    • Piver, M.S.1    Khalil, M.2    Emrich, L.J.3
  • 34
    • 0027165660 scopus 로고
    • Hydroxyurea versus misonidazole with radiation in cervical carcinoma: Long term follow-up of a Gynecologic Oncology Group trial
    • Stehman FB, Bundy BN, Thomas G et al. Hydroxyurea versus misonidazole with radiation in cervical carcinoma: long term follow-up of a Gynecologic Oncology Group trial. J Clin Oncol 1993; 11:1523-1528.
    • (1993) J Clin Oncol , vol.11 , pp. 1523-1528
    • Stehman, F.B.1    Bundy, B.N.2    Thomas, G.3
  • 35
    • 0027655796 scopus 로고
    • The clinical rationale for S-phase radiosensitization in human minors
    • McGinn CJ, Kinsella TJ. The clinical rationale for S-phase radiosensitization in human minors. Curr Prob Cancer 1993; 27:273-324.
    • (1993) Curr Prob Cancer , vol.27 , pp. 273-324
    • McGinn, C.J.1    Kinsella, T.J.2
  • 36
    • 0023264520 scopus 로고
    • Enhancement of X-ray induced DNA damage by pre-treatment with halogenated pyrimidine analogs
    • Kinsella TJ, Dobson PA, Mitchell JB, Fornace AJ. Enhancement of X-ray induced DNA damage by pre-treatment with halogenated pyrimidine analogs. Int J Radiat Oncol Biol Phys 1987; 13: 733-739.
    • (1987) Int J Radiat Oncol Biol Phys , vol.13 , pp. 733-739
    • Kinsella, T.J.1    Dobson, P.A.2    Mitchell, J.B.3    Fornace, A.J.4
  • 37
    • 0024371774 scopus 로고
    • Mechanism of radiosensitization by halogenated pyrimidines: Effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing
    • Iliakis G, Kurtzman S, Pantelias G, Okayasu R. Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing. Radiat Res 1989; 119:286-304.
    • (1989) Radiat Res , vol.119 , pp. 286-304
    • Iliakis, G.1    Kurtzman, S.2    Pantelias, G.3    Okayasu, R.4
  • 38
    • 0025327622 scopus 로고
    • Enhancement of radiation damage in cellular DNA following unifilar substitution with iododeoxyuridine
    • Fornace AJ, Dobson PP, Kinsella TJ. Enhancement of radiation damage in cellular DNA following unifilar substitution with iododeoxyuridine. Int J Radiat Oncol Biol Phys 1990; 18:873-878.
    • (1990) Int J Radiat Oncol Biol Phys , vol.18 , pp. 873-878
    • Fornace, A.J.1    Dobson, P.P.2    Kinsella, T.J.3
  • 39
    • 0025128324 scopus 로고
    • The effect of single versus double-strand substitution on halogenated pyrimidine-induced radiosensitization and DNA strand breakage in human tumor cells
    • Lawrence TS, Davis MN, Maybaum J, Stetson PL, Ensminger WD. The effect of single versus double-strand substitution on halogenated pyrimidine-induced radiosensitization and DNA strand breakage in human tumor cells. Radiat Res 1990; 123:192-198.
    • (1990) Radiat Res , vol.123 , pp. 192-198
    • Lawrence, T.S.1    Davis, M.N.2    Maybaum, J.3    Stetson, P.L.4    Ensminger, W.D.5
  • 40
    • 0025742796 scopus 로고
    • Mechanism of radiosensitization by halogenated pyrimidines: Bromodeoxyuridine and alpha-arabinofuranosyladenine affect similar subsets of radiation-induced potentially lethal lesions in plateau-phase Chinese hamster ovary cells
    • Iliakis G, Kurtzman S. Mechanism of radiosensitization by halogenated pyrimidines: bromodeoxyuridine and alpha-arabinofuranosyladenine affect similar subsets of radiation-induced potentially lethal lesions in plateau-phase Chinese hamster ovary cells. Radiat Res 1991; 127-45-51.
    • (1991) Radiat Res , vol.127 , pp. 45-51
    • Iliakis, G.1    Kurtzman, S.2
  • 41
    • 0026633463 scopus 로고
    • Linear-quadratic analysis of radiosensitization by halogenated pyrimidines. I. Radiosensitization of human colon cancer cells by iododeoxyuridine
    • Miller EM, Fowler JF, Kinsella TJ. Linear-quadratic analysis of radiosensitization by halogenated pyrimidines. I. Radiosensitization of human colon cancer cells by iododeoxyuridine. Radiat Res 1992; 131:81-89.
    • (1992) Radiat Res , vol.131 , pp. 81-89
    • Miller, E.M.1    Fowler, J.F.2    Kinsella, T.J.3
  • 42
    • 0001068772 scopus 로고
    • Iododeoxyuridine radiosensitization of human glioblastoma cells exposed to acute and chronic gamma irradiation: Mechanistic implications and clinical relevance
    • Schultz CJ, Gaffney DK, Lindstrom M, Kinsella TJ. Iododeoxyuridine radiosensitization of human glioblastoma cells exposed to acute and chronic gamma irradiation: mechanistic implications and clinical relevance. Cancer J Sci Am 1995; 1:151-161.
    • (1995) Cancer J Sci Am , vol.1 , pp. 151-161
    • Schultz, C.J.1    Gaffney, D.K.2    Lindstrom, M.3    Kinsella, T.J.4
  • 43
    • 0028821922 scopus 로고
    • Effect of bromodeoxyuridine on radiation-induced DNA damage and repair based on DNA fragment size using pulsed field gel electrophoresis
    • Lawrence TS, Davis MA, Normolle DP. Effect of bromodeoxyuridine on radiation-induced DNA damage and repair based on DNA fragment size using pulsed field gel electrophoresis. Radiat Res 1995; 144:282-287.
    • (1995) Radiat Res , vol.144 , pp. 282-287
    • Lawrence, T.S.1    Davis, M.A.2    Normolle, D.P.3
  • 44
    • 0029947035 scopus 로고    scopus 로고
    • The limiting radiosensitization of tumors by S-phase sensitizers
    • in press
    • Fowler JF, Kinsella TJ. The limiting radiosensitization of tumors by S-phase sensitizers. Br J Cancer 1996; 73: in press.
    • (1996) Br J Cancer , vol.73
    • Fowler, J.F.1    Kinsella, T.J.2
  • 45
    • 0028348423 scopus 로고
    • Kinetics of cell labeling and thymidine replacement after continuous infusion of halogenated pyrimidines in vivo
    • Rodriguez R, Ritter MA, Fowler JF, Kinsella TJ. Kinetics of cell labeling and thymidine replacement after continuous infusion of halogenated pyrimidines in vivo. Int J Radiat Oncol Biol Phys 1994; 29:105-113.
    • (1994) Int J Radiat Oncol Biol Phys , vol.29 , pp. 105-113
    • Rodriguez, R.1    Ritter, M.A.2    Fowler, J.F.3    Kinsella, T.J.4
  • 46
    • 0023815533 scopus 로고
    • Selective incorporation of iododeoxyuridine in DNA of hepatic metastases versus normal human liver
    • Speth PA, Kinsella TJ, Chang AE et al. Selective incorporation of iododeoxyuridine in DNA of hepatic metastases versus normal human liver. Clin Pharmacol Ther 1988; 44:369-375.
    • (1988) Clin Pharmacol Ther , vol.44 , pp. 369-375
    • Speth, P.A.1    Kinsella, T.J.2    Chang, A.E.3
  • 47
    • 0026508766 scopus 로고
    • Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusion of 5-iododeoxyuridine
    • Cook JA, Glass J, Lebovics R et al. Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusion of 5-iododeoxyuridine. Cancer Res 1992; 52:719-725.
    • (1992) Cancer Res , vol.52 , pp. 719-725
    • Cook, J.A.1    Glass, J.2    Lebovics, R.3
  • 48
    • 0029163013 scopus 로고
    • Incorporation of 5-bromo-2′-deoxyuridine into colorectal liver metastases and liver in patients receiving a 7-day hepatic arterial infusion
    • Knol JA, Walker SC, Robertson JM et al. Incorporation of 5-bromo-2′-deoxyuridine into colorectal liver metastases and liver in patients receiving a 7-day hepatic arterial infusion. Cancer Res 1995; 55:3687-3691.
    • (1995) Cancer Res , vol.55 , pp. 3687-3691
    • Knol, J.A.1    Walker, S.C.2    Robertson, J.M.3
  • 49
    • 2842555153 scopus 로고
    • Pharmacology and phase I/II study of continuous intravenous infusions of iododeoxyuridine and hyperfractionated radiotherapy in patients with glioblastoma multiforme
    • Kinsella TJ, Collins J, Rowland J et al. Pharmacology and phase I/II study of continuous intravenous infusions of iododeoxyuridine and hyperfractionated radiotherapy in patients with glioblastoma multiforme. J Clin Oncol 1988; 6871-6879.
    • (1988) J Clin Oncol , pp. 6871-6879
    • Kinsella, T.J.1    Collins, J.2    Rowland, J.3
  • 50
    • 0023767406 scopus 로고
    • Intra-arterial bromodeoxyuridine radiosensitization and radiation in treatment of malignant astrocytomas
    • Greenberg HS, Chandler WF, Diaz RF et al. Intra-arterial bromodeoxyuridine radiosensitization and radiation in treatment of malignant astrocytomas. J Neurosurg 1988; 69:500-505.
    • (1988) J Neurosurg , vol.69 , pp. 500-505
    • Greenberg, H.S.1    Chandler, W.F.2    Diaz, R.F.3
  • 51
    • 0025942266 scopus 로고
    • Evaluation of bromodeoxyuridine in glioblastoma multiforme: A Northern California Cancer Center phase II study
    • Phillips TL, Levin VA, Ahn DK et al. Evaluation of bromodeoxyuridine in glioblastoma multiforme: a Northern California Cancer Center phase II study. Int J Radiat Oncol Biol Phys 1991; 21: 709-714.
    • (1991) Int J Radiat Oncol Biol Phys , vol.21 , pp. 709-714
    • Phillips, T.L.1    Levin, V.A.2    Ahn, D.K.3
  • 52
    • 0028021915 scopus 로고
    • National Cancer Institute (Phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: Encouraging results in anaplastic astrocytoma
    • Sullivan FJ, Herscher LL, Cook JA et al. National Cancer Institute (Phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: encouraging results in anaplastic astrocytoma. Int J Radiat Oncol Biol Phys 1994; 30:583-590.
    • (1994) Int J Radiat Oncol Biol Phys , vol.30 , pp. 583-590
    • Sullivan, F.J.1    Herscher, L.L.2    Cook, J.A.3
  • 53
    • 0028911680 scopus 로고
    • Radiation therapy and bromodeoxyuridine chemotherapy followed by procarbazine, lomustine and vincristine for the treatment of anaplastic gliomas
    • Levin VA, Prados MD, Wara WM et al. Radiation therapy and bromodeoxyuridine chemotherapy followed by procarbazine, lomustine and vincristine for the treatment of anaplastic gliomas. Int J Radiat Oncol Biol Phys 1995; 32:75-83.
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , pp. 75-83
    • Levin, V.A.1    Prados, M.D.2    Wara, W.M.3
  • 54
    • 17744417493 scopus 로고    scopus 로고
    • Survival improvement in anaplastic astrocytoma combining external radiation with halogenated pyrimidines. Final report of RTOG 86-12, phase I-II study
    • in press
    • Urtasun RC, Kinsella TJ, DelRowe J et al. Survival improvement in anaplastic astrocytoma combining external radiation with halogenated pyrimidines. Final report of RTOG 86-12, phase I-II study. Int J Radiat Oncol Biol Phys 1996; 35: in press.
    • (1996) Int J Radiat Oncol Biol Phys , vol.35
    • Urtasun, R.C.1    Kinsella, T.J.2    DelRowe, J.3
  • 55
    • 0028284681 scopus 로고
    • Kinetics of bromodeoxyuridine elimination from human colon cancer cells in vitro and in vivo
    • Lawrence TS, Davis MA, Stetson PL et al. Kinetics of bromodeoxyuridine elimination from human colon cancer cells in vitro and in vivo. Cancer Res 1994; 54:2964-2968.
    • (1994) Cancer Res , vol.54 , pp. 2964-2968
    • Lawrence, T.S.1    Davis, M.A.2    Stetson, P.L.3
  • 56
    • 0010638865 scopus 로고
    • A phase I/II study of bromodeoxyuridine (BrdU) and radiation therapy (RT) for locally advanced cervix cancer
    • Robertson JR, Johnston C, Eisbruch A et al. A phase I/II study of bromodeoxyuridine (BrdU) and radiation therapy (RT) for locally advanced cervix cancer. Proc Am Soc Clin Oncol 1995; 14:201.
    • (1995) Proc Am Soc Clin Oncol , vol.14 , pp. 201
    • Robertson, J.R.1    Johnston, C.2    Eisbruch, A.3
  • 57
    • 0028948438 scopus 로고
    • Effects of 5′-aminothymidine and leucovorin on the radiosensitization by iododeoxyuridine in human colon cancer cells
    • Miller EM, Kunugi KA, Kinsella TJ. Effects of 5′-aminothymidine and leucovorin on the radiosensitization by iododeoxyuridine in human colon cancer cells. Clin Cancer Res 1995; 1:407-416.
    • (1995) Clin Cancer Res , vol.1 , pp. 407-416
    • Miller, E.M.1    Kunugi, K.A.2    Kinsella, T.J.3
  • 58
    • 0029950209 scopus 로고    scopus 로고
    • In vivo modulation of 5-iododeoxyuridine metabolism and incorporation into cellular DNA by 5′-amino-5′-deoxythymidine in normal mouse tissues and two human colon cancer xenografts
    • in press
    • Kinsella TJ, Glennon MC, Kunugi KA, Lindstrom MJ. In vivo modulation of 5-iododeoxyuridine metabolism and incorporation into cellular DNA by 5′-amino-5′-deoxythymidine in normal mouse tissues and two human colon cancer xenografts. Clin Cancer Res 1996; 2 in press.
    • (1996) Clin Cancer Res , vol.2
    • Kinsella, T.J.1    Glennon, M.C.2    Kunugi, K.A.3    Lindstrom, M.J.4
  • 59
    • 0028337391 scopus 로고
    • In vivo comparison of oral 5-iodo-2′-deoxyuridine and 5-iodo-2-pyrimidinone-2′-deoxyribose toxicity, pharmacokinetics, and DNA incorporation in athymic mouse tissues and a human colon cancer xenograft (HCT-116)
    • Kinsella TJ, Kunugi KA, Vielhuber K et al. In vivo comparison of oral 5-iodo-2′-deoxyuridine and 5-iodo-2-pyrimidinone-2′-deoxyribose toxicity, pharmacokinetics, and DNA incorporation in athymic mouse tissues and a human colon cancer xenograft (HCT-116). Cancer Res 1994; 54:2695-2700.
    • (1994) Cancer Res , vol.54 , pp. 2695-2700
    • Kinsella, T.J.1    Kunugi, K.A.2    Vielhuber, K.3
  • 60
    • 2842516171 scopus 로고    scopus 로고
    • Preclinical evaluation of 5-iodo-2-pyrimidinone-2′-deoxyribose (IPdR) as a prodrug for iododeoxyuridine (IUdR)-radiosensitization in mouse and human tissues
    • Kinsella TJ, Kunugi KA, Vielhuber K et al. Preclinical evaluation of 5-iodo-2-pyrimidinone-2′-deoxyribose (IPdR) as a prodrug for iododeoxyuridine (IUdR)-radiosensitization in mouse and human tissues. Proc Am Assoc Cancer Res 1996; 37:612.
    • (1996) Proc Am Assoc Cancer Res , vol.37 , pp. 612
    • Kinsella, T.J.1    Kunugi, K.A.2    Vielhuber, K.3
  • 61
    • 0025651424 scopus 로고
    • Fluorodeoxyuridine-induced radiosensitization and inhibition of DNA double strand break repair in human colon cancer cells
    • Bruso CE, Shewach DS, Lawrence TS. Fluorodeoxyuridine-induced radiosensitization and inhibition of DNA double strand break repair in human colon cancer cells. Int J Radiat Oncol Biol Phys 1990; 19:1411-1417.
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 1411-1417
    • Bruso, C.E.1    Shewach, D.S.2    Lawrence, T.S.3
  • 62
    • 0025986853 scopus 로고
    • The effect of fluorodeoxyuridine on sublethal damage repair in human colon cancer cells
    • Heimburger DK, Shewach DS, Lawrence TS. The effect of fluorodeoxyuridine on sublethal damage repair in human colon cancer cells. Int J Radiat Oncol Biol Phys 1991; 21:983-987.
    • (1991) Int J Radiat Oncol Biol Phys , vol.21 , pp. 983-987
    • Heimburger, D.K.1    Shewach, D.S.2    Lawrence, T.S.3
  • 63
    • 0027497460 scopus 로고
    • Fluoropyrimidines as radiation sensitizers
    • Lawrence TS, Maybaum J. Fluoropyrimidines as radiation sensitizers. Sem Radiat Oncol 1993; 3:20-28.
    • (1993) Sem Radiat Oncol , vol.3 , pp. 20-28
    • Lawrence, T.S.1    Maybaum, J.2
  • 64
    • 0011234930 scopus 로고    scopus 로고
    • Studies on fluorinated pyrimidines II. Effects on transplanted tumors
    • 958
    • Heidelberger C, Griesbach L, Montag BJ et al. Studies on fluorinated pyrimidines II. Effects on transplanted tumors. Cancer Res 958; 18:305-309.
    • Cancer Res , vol.18 , pp. 305-309
    • Heidelberger, C.1    Griesbach, L.2    Montag, B.J.3
  • 65
    • 0024227159 scopus 로고
    • Adjuvant postoperative radiotherapy and chemotherapy in rectal carcinoma: A review of the Gastrointestinal Tumor Study Group experience
    • Thomas PR, Lindblad AS. Adjuvant postoperative radiotherapy and chemotherapy in rectal carcinoma: a review of the Gastrointestinal Tumor Study Group experience. Radiother Oncol 1988; 13:245-252.
    • (1988) Radiother Oncol , vol.13 , pp. 245-252
    • Thomas, P.R.1    Lindblad, A.S.2
  • 66
    • 0023262033 scopus 로고
    • Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer
    • Gastrointestinal Tumor Study Group: Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer 1987; 59:2006-2010.
    • (1987) Cancer , vol.59 , pp. 2006-2010
  • 67
    • 0026603462 scopus 로고
    • Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum
    • Gastrointestinal Tumor Study Group. Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum. J Clin Oncol 1992; 10:549-557.
    • (1992) J Clin Oncol , vol.10 , pp. 549-557
  • 68
    • 0026071185 scopus 로고
    • Effective surgical adjuvant therapy for high-risk rectal carcinoma
    • Krook JE, Moertel CG, Gunderson LL et al. Effective surgical adjuvant therapy for high-risk rectal carcinoma. N Engl J Med 1991; 324:709-715.
    • (1991) N Engl J Med , vol.324 , pp. 709-715
    • Krook, J.E.1    Moertel, C.G.2    Gunderson, L.L.3
  • 69
    • 0028136295 scopus 로고
    • Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery
    • O'Connell MJ, Martenson JA, Wieand HS et al. Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med 1994; 33:502-507.
    • (1994) N Engl J Med , vol.33 , pp. 502-507
    • O'Connell, M.J.1    Martenson, J.A.2    Wieand, H.S.3
  • 70
    • 0026769381 scopus 로고
    • Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus
    • Herskovic A, Martz K, al-Sarraf M et al. Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus. N Engl J Med 1992; 24:1593-1598.
    • (1992) N Engl J Med , vol.24 , pp. 1593-1598
    • Herskovic, A.1    Martz, K.2    Al-Sarraf, M.3
  • 71
    • 0025710611 scopus 로고
    • NIH consensus conference. Adjuvant therapy for patients with colon and rectal cancer
    • Anonymous. NIH consensus conference. Adjuvant therapy for patients with colon and rectal cancer. JAMA 1990; 264:1444-1450.
    • (1990) JAMA , vol.264 , pp. 1444-1450
  • 72
    • 0020393438 scopus 로고
    • Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and x rays
    • Byfield JE, Calabro-Jones P, Klisak LL, Kulhanian F. Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and x rays. Int J Radiat Oncol Biol Phys 1982; 8:1923-1933.
    • (1982) Int J Radiat Oncol Biol Phys , vol.8 , pp. 1923-1933
    • Byfield, J.E.1    Calabro-Jones, P.2    Klisak, L.L.3    Kulhanian, F.4
  • 73
    • 85053094428 scopus 로고
    • Useful interactions between 5-fluorouracil and radiation in man: 5-fluorouracil as a radiosensitizer
    • Hill BT, Bellamy AS, eds. Boca Raton, Fla: CRC Press Inc.
    • Byfield JE. Useful interactions between 5-fluorouracil and radiation in man: 5-fluorouracil as a radiosensitizer. In: Hill BT, Bellamy AS, eds. Antitumor Drug-Radiation Interactions. Boca Raton, Fla: CRC Press Inc., 1990:87-105.
    • (1990) Antitumor Drug-Radiation Interactions , pp. 87-105
    • Byfield, J.E.1
  • 74
    • 0022492252 scopus 로고
    • Growth delay in a murine squamous cell tumor after local radiation and concurrent infusional 5-fluorouracil treatment
    • Weinberg MJ, Lapointe TA, Rauth AM. Growth delay in a murine squamous cell tumor after local radiation and concurrent infusional 5-fluorouracil treatment. Int J Radiat Oncol Biol Phys 1986; 12:1449-1452.
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 1449-1452
    • Weinberg, M.J.1    Lapointe, T.A.2    Rauth, A.M.3
  • 75
    • 0023161992 scopus 로고
    • 5-Fluorouracil infusion and fractionated dose of radiation: Studies with a murine squamous cell carcinoma
    • Weinberg MJ, Rauth AM. 5-Fluorouracil infusion and fractionated dose of radiation: studies with a murine squamous cell carcinoma. Im J Radiat Oncol Biol Phys 1987; 13:1691-1699.
    • (1987) Im J Radiat Oncol Biol Phys , vol.13 , pp. 1691-1699
    • Weinberg, M.J.1    Rauth, A.M.2
  • 76
    • 0028245382 scopus 로고
    • Dependence of 5-fluorouracil-mediated radiosensitization on DNA-directed effects
    • Lawrence TS, Davis MA, Maybaum J. Dependence of 5-fluorouracil-mediated radiosensitization on DNA-directed effects. Int J Radiat Oncol Biol Phys 1994; 29:59-523.
    • (1994) Int J Radiat Oncol Biol Phys , vol.29 , pp. 59-523
    • Lawrence, T.S.1    Davis, M.A.2    Maybaum, J.3
  • 77
    • 0029058456 scopus 로고
    • Dependence of fluorodeoxyuridine-mediated radiosensitization on S phase progression
    • Davis MA, Tang HY, Maybaum J, Lawrence TS. Dependence of fluorodeoxyuridine-mediated radiosensitization on S phase progression. Int J Radiat Biol 1995; 67:509-512.
    • (1995) Int J Radiat Biol , vol.67 , pp. 509-512
    • Davis, M.A.1    Tang, H.Y.2    Maybaum, J.3    Lawrence, T.S.4
  • 78
    • 0028019863 scopus 로고
    • The role of cell cycle redistribution in radiosensitization: Implications regarding the mechanism of fluorodeoxyuridine radiosensitization
    • McGinn CJ, Miller EM, Lindstrom MJ et al. The role of cell cycle redistribution in radiosensitization: implications regarding the mechanism of fluorodeoxyuridine radiosensitization. Int J Radiat Oncol Biol Phys 1994; 30:851-859.
    • (1994) Int J Radiat Oncol Biol Phys , vol.30 , pp. 851-859
    • McGinn, C.J.1    Miller, E.M.2    Lindstrom, M.J.3
  • 79
    • 0027181763 scopus 로고
    • The thymidylate synthase inhibitor, ICI D1694, overcomes translational detainment of the enzyme
    • Keyomarsi K, Samet J, Molinar G, Pardee AB. The thymidylate synthase inhibitor, ICI D1694, overcomes translational detainment of the enzyme. J Biol Chem 1993; 268:15142-15149.
    • (1993) J Biol Chem , vol.268 , pp. 15142-15149
    • Keyomarsi, K.1    Samet, J.2    Molinar, G.3    Pardee, A.B.4
  • 80
    • 0012523788 scopus 로고
    • Tomudex (ZD 1694), a new thymidylate synthase inhibitor with antitumor activity in breast cancer
    • Smith IE, Speilmann M, Bonneterre J et al. Tomudex (ZD 1694), a new thymidylate synthase inhibitor with antitumor activity in breast cancer. Ann Oncol 1994; 5:242-249.
    • (1994) Ann Oncol , vol.5 , pp. 242-249
    • Smith, I.E.1    Speilmann, M.2    Bonneterre, J.3
  • 81
    • 0001252836 scopus 로고
    • Tomudex (ZD 1694): Results of a randomized trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leucopenia
    • Cunningham D, Zalcberg JR, Rath U et al. Tomudex (ZD 1694): Results of a randomized trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leucopenia. Eur J Cancer 1995; 31:1945-1954.
    • (1995) Eur J Cancer , vol.31 , pp. 1945-1954
    • Cunningham, D.1    Zalcberg, J.R.2    Rath, U.3
  • 82
  • 83
    • 0026778383 scopus 로고
    • Mechanism of action of hydroxyurea
    • Yarbro JW. Mechanism of action of hydroxyurea. Semin Oncol 1992;19(S9):1-10.
    • (1992) Semin Oncol , vol.19 , Issue.S9 , pp. 1-10
    • Yarbro, J.W.1
  • 84
    • 0026755811 scopus 로고
    • An overview of the clinical experience with hydroxyurea
    • Donehower RC. An overview of the clinical experience with hydroxyurea. Semin Oncol 1992; 19 (S9):11-19.
    • (1992) Semin Oncol , vol.19 , Issue.S9 , pp. 11-19
    • Donehower, R.C.1
  • 85
    • 0027054126 scopus 로고
    • The interaction of 5-fluorouracil, hydroxyurea, and radiation in two human head and neck cancer cell lines
    • Vokes EE, Beckett M, Karrison T, Weichselbaum RR. The interaction of 5-fluorouracil, hydroxyurea, and radiation in two human head and neck cancer cell lines. Oncology 1992; 49:454-460.
    • (1992) Oncology , vol.49 , pp. 454-460
    • Vokes, E.E.1    Beckett, M.2    Karrison, T.3    Weichselbaum, R.R.4


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