Indium- or zinc-mediated one-pot synthesis of homoallylamines, β-amino esters, and β-amino nitriles

Organic Letters

Volumn 2, Issue 13, 2000, Pages 1851-1853

  Choucair, Bassima ^a   Léon, Hervé ^a   Miré, Marcelle Astrid ^a   Lebreton, Chrystèle ^a   Mosset, Paul ^a  

^a UNIV RENNES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000973672     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol005912k     Document Type: Article

References (22)

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17. 4 were used to ensure complete conversion of the aldehyde.
18. This was visualized by immediate foaming. Omitting this operation resulted thereafter in far lower yields of 2.
19. 4 Use of 1 equiv of indium led to no significant increase of yields.
20. A 1.25 equiv portion of zinc was used.
21. 4 therefore acting as a dehydrating agent.
22. Krasik, P. Tetrahedron Lett. 1998, 39, 4223-4226 and ref. cited.