Characterizing mammalian cells and cell phantoms by polarized backscattering fiber–optic measurements

Applied Optics

Volumn 40, Issue 28, 2001, Pages 5114-5123

  Mourant, Judith R ^a,b   Johnson, Tamara M ^a,b   Freyer, James P ^a,b  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ELECTROMAGNETIC WAVE BACKSCATTERING; LIGHT POLARIZATION; LIGHT SCATTERING; POLYSTYRENES;

MAMMALIAN CELLS;

FIBER OPTICS;

EID: 0000945964     PISSN: 1559128X     EISSN: 21553165     Source Type: Journal    
DOI: 10.1364/AO.40.005114     Document Type: Article

References (25)

1. S. L. Jacques, J. R. Roman, and K. Lee, “Imaging superficial tissues with polarized light,” Lasers Surg. Med. 26, 119-129 (2000).
2. V. Backman, R. Guijar, K. Badizadegan, I. Itzkan, R. R. Dasari, L. T. Perelman, and M. S. Feld, “Polarized light scattering spectroscopy for quantitative measurement of epithelial cellular structures in situ,” IEEE J. Sel. Top. Quantum Electron. 5, 1019-1026 (1999).
3. K. Sokolov, R. Drezek, K. Gossage, and R. Richards-Kortum, “Reflectance spectroscopy with polarized light: is it sensitive to cellular and nuclear morphology,” Opt. Express 5, 302-317 (1999), http://www.opticsexpress.org.
4. R. S. Cotran, V. Kumar, and S. L. Robbins, Pathological Basis of Disease (Saunders, Philadelphia, Pa., 1994), Chap. 7.
5. R. Drezek, A. Dunn, and R. Richards-Kortum, “A pulsed finite-difference time-domain (FDTD) method for calculating light scattering from biological cells over broad wavelength ranges,” Opt. Express 6, 147-157 (2000), http://www.opticsexpress.org.
6. J. Mourant, J. Freyer, A. Hielscher, A. Eick, D. Shen, and T. Johnson, “Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics,” Appl. Opt. 37, 3586-3593 (1998).
7. T. M. Johnson and J. R. Mourant, “Polarized wavelength-dependent measurements of turbid media,” Opt. Express 4, 200 -216 (1999), http://www.opticsexpress.org.
8. J. R. Mourant, M. Canpolat, C. Brocker, O. Esponda-Ramos, T. Johnson, A. Matanock, K. Stetter, and J. P. Freyer, “Light scattering from cells: the contribution of the nucleus and the effects of proliferative status,” J. Biomed. Opt. 5, 131-137 (2000).
9. G. Marquez, L. V. Wang, S.-P. Lin, J. A. Schwartz, and S. L. Thomsen, “Anisotropy in the absorption and scattering spectra of chicken breast tissue,” Appl. Opt. 37, 798-804 (1998).
10. C. F. Bohren and D. R. Hoffman, Absorption and Scattering of Light by Small Particles (Wiley, New York, 1983).
11. J. R. Mourant, J. P. Freyer, A. H. Hielscher, A. A. Eick, D. Shen, and T. M. Johnson, “Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics,” Appl. Opt. 37, 3586-3593 (1998).
12. S. Bartel and A. H. Hielscher, “Monte Carlo simulation of the diffuse backscattering Mueller matrix for highly scattering media,” Appl. Opt. 39, 1580-1588 (2000).
13. J. R. Mourant, J. Boyer, A. H. Hielscher, and I. J. Bigio, “Influence of the scattering phase function on light transport measurements in turbid media performed with small source-detector separations,” Opt. Lett. 21, 546-548 (1996).
14. S. L. Jacques and L. Wang, “Monte Carlo modeling of light transport in tissues,” in Optical-Thermal Response of Laser Irradiated Tissue, A. J. Welch and M. J. C. van Gemert, eds. (Plenum, New York, 1995), pp. 73-100.
15. M. J. Rackovich, G. W. Kattawar, M. Mehrubeoglu, B. D. Cameron, L. V. Wang, S. Rasategar, and G. L. Cote, “Light backscattering polarization patterns from turbid media: theory and experiments,” Appl. Opt. 38, 3399-3408 (1999).
16. B. D. Cameron, M. J. Rakovic, M. Mehrubeoglu, G. W. Kattawar, S. Rastegar, L. V. Wang, and G. L. Cote, “Measurement and calculation of the two-dimensional backscattering Mueller matrix of a turbid medium,” Opt. Lett. 23, 485-487 (1998).
17. B. D. Cameron, M. J. Rakovic, M. Mehrubeoglu, G. W. Kattawar, S. Rastegar, L. V. Wang, and G. L. Cote, “Measurement and calculation of the two-dimensional backscattering Mueller matrix of a turbid medium: errata,” Opt. Lett. 23, 1630 (1998).
18. S. Asano and M. Sato, “Light scattering by randomly oriented spheroidal particles,” Appl. Opt. 19, 962-974 (1980).
19. A. Dogariu, M. Dogariu, K. Richardson, S. D. Jacobs, and G. D. Boreman, “Polarization asymmetry in waves backscattering from highly absorbant random media,” Appl. Opt. 36, 8159 -8167 (1997).
20. M. Dogariu and T. Asakura, “Polarization-dependent backscattering patterns from weakly scattering media,” J. Opt. (Paris) 24, 271-278 (1993).
21. J. M. Schmitt and G. Kumar, “Optical scattering properties of soft tissue: a discrete particle model,” Appl. Opt. 37, 2788-2797 (1998).
22. M. J. Holbroke, B. J. Tromberg, X. Li, N. Shah, D. Kidney, J. Butler, B. Chance, and A. G. Yodh, “Three-dimensional diffuse optical mammography with ultrasound localization in a human subject,” J. Biomed. Opt. 5, 237-247 (2000).
23. A. Brunsting and P. Mullaney, “Differential light scattering from spherical mammalian cells,” Biopys. J. 14, 439-453 (1974).
24. H. Liu, B. Beauvoit, M. Kimura, and B. Chance, “Dependence of tissue optical properties of solute-induced changes in refractive index and osmolarity,” J. Biomed. Opt. 1, 200-211 (1996).
25. M. Canpolat and J. R. Mourant, “High-angle scattering events strongly affect light collection in clinically relevant measurement geometries for light transport through tissue,” Phys. Med. Biol. 45, 1127-1140 (2000).