Carrier-mediated GABA release: Is there a functional role?

Neuroscientist

Volumn 3, Issue 3, 1997, Pages 151-157

  Richerson, George B ^a   Gaspary, Heidi L ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Anticonvulsants; Antiepilepsy drugs; Epilepsy; Seizures; Synapse

Indexed keywords

EID: 0000934452     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/107385849700300307     Document Type: Review

References (41)

1. Kocsis JD, Mattson RH. GABA levels in the brain: a target for new antiepileptic drugs. NEUROSCIENTIST 1996;2:326-334.
2. Israel M, Dunant Y, Manaranche R. The present status of the vesicular hypothesis. Prog Neurobiol 1979;13:237-275.
3. Taue L. Nonvesicular release of neurotransmitter. Physiol Rev 1982;62:857-893.
4. Israel M, Morel N, Lesbats B, Birman S, Manaranche R. Purification of a presynaptic membrane protein that mediates a calcium-dependent translocation of acetylcholine. Proc Natl Acad Sci U S A 1986; 83:9226-9230.
5. Israel M, Dunant Y. A unifying hypothesis for acetylcholine release. Neurochem Int 1996;28:1-9.
6. Erxleben C, Kriebel ME. Subunit composition of the spontaneous miniature end-plate currents at the mouse neuromuscular junction. J Physiol (Lond) 1988; 400:659-676.
7. Van der Kloot W. Acetylcholine quanta are released from vesicles by exocytosis (and why some think not). Neuroscience 1988;24:1-7.
8. Van der Kloot W. Statistical and graphical methods for testing the hypothesis that quanta are made up of subunits. J Neurosci Methods 1989;27:81-89.
9. Matteoli M, DeCamilli P. Molecular mechanisms in neurotransmitter release. Curr Opin Neurobiol 1991;1:91-97.
10. Sudhof TC. The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature 1995;375:645-653.
11. Sudhof TC, Jahn R. Proteins of synaptic vesicles involved in exocytosis and membrane recycling. Neuron 1991;6:665-677.
12. Del Castillo J, Katz B. La base "quantale" de la transmission neuromusculaire. In: Microphysiologie comparee des elements excitables. Paris: Centre Natl. Rech. Sci. Colloq. Int. 1957;245-58.
13. Katz B, Miledi R. The quantal release of transmitter substances. In: Curtis DR, McIntyre AK, editors. Studies in physiology. Berlin: Springer, 1965;118-25.
14. Katz B, Miledi R. Transmitter leakage from motor nerve endings. Proc R Soc Lond B Biol Sci 1977;196:59-72.
15. Yazulla S, Kleinschmidt J. Carrier-mediated release of GABA from retinal horizontal cells. Brain Res 1983;263:63-75.
16. Schwartz EA. Depolarization without calcium can release gamma-aminobutyric acid from a retinal neuron. Science 1987; 238:350-355.
17. Taylor J, Gordon-Weeks PR. Calcium-independent gamma-aminobutyric acid release from growth cones: role of gamma-aminobutyric acid transport. J Neurochem 1991;56:273-280.
18. Gallo V, Patrizio M, Levi G. GABA release triggered by the activation of neuron-like non-NMDA receptors in cultured type 2 astrocytes is carrier-mediated. Glia 1991;4:245-255.
19. Levi G, Raiteri M. Carrier-mediated release of neurotransmitters. Trends Neurosci 1993;16:415-419.
20. Pin JP, Bockaert J. Two distinct mechanisms, differentially affected by excitatory amino acids, trigger GABA release from fetal mouse striatal neurons in primary culture. J Neurosci 1989;9:648-656.
21. Collingridge GL, Davies J. The in vitro inhibition of GABA release by tetanus toxin. Neuropharmacology 1982;21:851-855.
22. Van Vliet BJ, Sebben M, Dumuis A, Gabrion J, Bockaert J, Pin JP. Endogenous amino acid release from cultured cerebellar neuronal cells: effect of tetanus toxin on glutamate release. J Neurochem 1989;52:1229-1239.
23. 3H] GABA release from developing cell cultures of the rat cerebellum. J Neurochem 1983;40:887-890.
24. Schiavo G, Benfenati F, Poulain B, et al. Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin. Nature 1992;359:832-835.
25. Humphreys CJ, Beidler D, Rudnick G. Substrate and inhibitor binding and translocation by the platelet plasma membrane serotonin transporter. Biochem Soc Trans 1991;19:95-98.
26. Lester HA, Mager S, Quick MW, Corey JL. Permeation properties of neurotransmitter transporters. Annu Rev Pharmacol 1994;34:219-249.
27. Liu QR, Lopez-Corcuera B, Mandiyan S, Nelson H, Nelson N. Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain [corrected] [published erratum appears in J Biol Chem 1993 268(12):9156]. J Biol Chem 1993;268: 2106-2112.
28. Clark JA, Deutch AY, Gallipoli PZ, Amara SG. Functional expression and CNS distribution of a beta-alanine-sensitive neuronal GABA transporter. Neuron 1992;9:337-348.
29. Swan M, Najlerahim A, Watson RE, Bennett JP. Distribution of mRNA for the GABA transporter GAT-1 in the rat brain: evidence that GABA uptake is not limited to presynaptic neurons. J Anat 1994;185: 315-323.
30. 3H]-gamma-aminobutyric acid release resolved by a rapid superfusion system. Biochemistry 1989; 28:586-593.
31. 3H]GABA release from striatal slices: evidence for a calcium-independent process via the GABA uptake system. Neuroscience 1988;27:563-570.
32. Kanner BI, Schuldiner S. Mechanism of transport and storage of neurotransmitters. CRC Crit Rev Biochem 1987;22:1-38.
33. Mager S, Naeve J, Quick M, Labarca C, Davidson N, Lester HA. Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes. Neuron 1993;10:177-188.
34. Cammack JN, Rakhilin SV, Schwartz EA. A GABA transporter operates asymmetrically and with variable stoichiometry. Neuron 1994;13:949-960.
35. Rose CR, Ransom BR. Intracellular sodium homeostasis in rat hippocampal astrocytes. J Physiol (Lond) 1996;491:291-305.
36. + changes induced by glutamate, kainate, and D-aspartate in rat hippocampal astrocytes. J Neurosci 1996;16:5393-5404.
37. Solis JM, Nicoll RA. Postsynaptic action of endogenous GABA released by nipecotic acid in the hippocampus. Neurosci Lett 1992;147:16-20.
38. Honmou O, Kocsis JD, Richerson GB. Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro. Epilepsy Res 1995;20:193-202.
39. o increases whole cell conductance in hippocampal neurons. Soc Neurosci Abstr 1997; in press.
40. Levi AJ. The effect of strophanthidin on action potential, calcium current and contraction in isolated guinea-pig ventricular myocytes. J Physiol (Lond) 1991;443:1-23.
41. + concentration in isolated nerve terminals following metabolic inhibition: possible relevance to hypoglycaemia and anoxia. Neuroscience 1988;27:175-182.