Bis(2,2,2-trifluoroethyl)bromophosphono-acetate, a novel HWE reagent for the preparation of (E)-α-bromoacrylates: A general and stereoselective method for the synthesis of trisubstituted alkenes

Organic Letters

Volumn 2, Issue 13, 2000, Pages 1975-1978

  Tago, Keiko ^a   Kogen, Hiroshi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000471368     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol006074x     Document Type: Article

References (34)

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31. 2O, which was purchased from Aldrich Chemical Co., gave the best result for reduction.
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34. Geometry of α-bromoacrylates were determined by NOE analysis of the allylic alcohol which was derived from DIBAL-H reduction of corresponding ester.