An investigation of a possible role for mitochondrial nuclease in apoptosis

Apoptosis

Volumn 3, Issue 6, 1998, Pages 395-405

  Meng, X W ^a   Fraser, M J ^a,b   Ireland, C M ^a   Feller, J M ^a   Ziegler, J B ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b SYDNEY CHILDREN'S HOSPITAL   (Australia)

Author keywords

Apoptosis; Etoposide; Hydroxychloroquine; Mitochondria; Nuclease; Transmembrane potential

Indexed keywords

EID: 0000458271     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1009654418089     Document Type: Article

References (32)

1. Fraser MJ, Low RL. Fungal and mitochondrial nucleases. In: Roberts RJ, Linn SM, Lloyd RS, eds. Nucleases, Second Edition. Cold Spring Harbor, NY (USA): Cold Spring Harbor Laboratory Press, 1993: 171-207.
2. Cummings OW, King TC, Holden JA, Low RL. Purification and characterization of the potent endonuclease in extracts of bovine heart mitochondria. J Biol Chem 1987; 262: 2005-2015.
3. n sequences by endonuclease G. Characterization of the calf thymus nuclease. J Biol Chem 1989; 264: 3301-3310.
4. Cote J, Ruiz-Carillo A. Primers for mitochondrial DNA replication generated by endonuclease G. Science 1993; 261: 765-769.
5. Gerschenson M, Houmiel KL, Low RL. Endonuclease G from mammalian nuclei is identical to the major endonuclease of mitochondria. Nucl Acids Res 1995; 23: 88-97.
6. Dake E, Hofmann TJ, McIntire S, Hudson A, Zassenhaus HP. Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 1988; 263: 7691-7702.
7. Ikeda S, Hasegawa H, Kaminaka S. A 55-kDa endonuclease of mammalian mitochondria: Comparison of its subcellular localization and endonucleolytic properties with those of endonuclease G. Acta Med Okayama 1997; 51: 55-62.
8. Murgia M, Pizzo P, Sandona D, Zanovello P, Rizzuto R, Di Virgilio F. Mitochondnal DNA is not fragmented during apoptosis. J Biol Chem 1992; 267: 10939-10941.
9. Tepper CG, Studzinski GP. Teniposide induces nuclear but not mitochondrial DNA degradation. Cancer Res 1992; 52: 3384-3390.
10. Susin SA, Zamzami N, Castedo M, et al. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 1996; 184: 1331-1341.
11. Susin SA, Zamzami N, Castedo M, et al. The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/APO-l/CD95- and ceramide-induced apoptosis. J Exp Med 1997; 186: 25-37.
12. Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c. Cell 1996; 86: 147-157.
13. Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479-489.
14. Bossy-Wetzel E, Newmeyer DD, Green DR. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J 1998; 17: 37-49.
15. De Vos K, Gossens V, Boone E, et al. The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region. J Biol Chem 1998; 273: 9673-9680.
16. Walker PR, Sikorska M. New aspects of the mechanism of DNA fragmentation in apoptosis. Biochem Cell Biol 1997; 75: 287-299.
17. Fraser MJ, Tynan SJ, Papaioannou A, Ireland CM, Pittman SM. Endo-exonuclease of human leukaemic cells: evidence for a role in apoptosis. J Cell Sci 1996; 109: 2343-2360.
18. Enari M, Sakahira H, Yokoyama K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998; 391: 43-50.
19. Martins LM, Mesner PW, Kottke TJ, et al. Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis. Blood 1997; 90: 4283-4296.
20. Saeki K, Akira Y, Kato M, Miyazono K, Yakazaki Y, Takaku F. Cell density-dependent apoptosis in HL-60 cells, which is mediated by an unknown soluble factor, is inhibited by transforming growth factor b1 and overexpression of Bcl-2. J Biol Chem 1997; 272: 20003-20010.
21. Xiang J, Chao DT, Korsmeyer SJ. Bax-induced cell death may not require interleukin 1b-converting enzyme-like proteases. Proc Natl Acad Sci USA 1996; 93: 14559-14563.
22. Adjei PN, Kaufmann SH, Leung W-Y, Mao F, Gores GJ. Selective induction of apoptosis in Hep 3B cells by topoisomerase inhibitors: Evidence for a protease-dependent pathway that does not activate cysteine protease P32. J Clin Invest 1996; 98: 2588-2596.
23. Lavoie JN, Nguyen M, Marcellus, RC, Branton PE, Shore GC. E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by z-VAD-fmk. J Cell Biol 1998; 140: 637-645.
24. Meng XW, Feller JM, Ziegler JB, Pittman SM, Ireland CM. Induction of apoptosis in peripheral blood lymphocytes following treatment in vitro with hydroxychloroquine. Arthritis Rheum 1997; 40: 927-935.
25. Macho A, Decaudin D, Castedo M, et al. Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis. Cytometry 1996; 25: 333-340.
26. Bogenhagen D, Clayton DA. The number of mitochondrial deoxyribonucleic acid genomes in mouse L and human HeLa cells. Quantitative isolation of mitochondrial deoxyribonucleic acid. J Biol Chem 1974; 249: 7991-7995.
27. Anderson A, Bankier AT, Barrell BG, et al. Sequence and organization of the human mitochondrial genome. Nature 1981; 290: 457-465.
28. Meinkoth J, Wahl G. Hybridization of nucleic acids immobilized on solid supports. Anal Biochem 1984; 138: 267-284.
29. Chauhan D, Pandey P, Ogata A, et al. Cytochrome c-dependent and -independent induction of apoptosis in multiple myeloma cells. J Biol Chem 1997; 272: 29995-29997.
30. Tang DG, Li L, Zhu Z, Joshi B. Apoptosis in the absence of cytochrome c accumulation in the cytosol. Biochem Biophys Res Commun 1998; 242: 380-384.
31. Barry MA, Eastman A. Identification of deoxyribonuclease II as an endonuclease involved in apoptosis. Arch Biochem Biophys 1993; 300: 440-450.
32. Collins MKL, Furlong IJ, Malde P, Ascaso R, Oliver J, Rivas AL. An apoptotic endonuclease activated either by decreasing pH or by increasing calcium. J Cell Sci 1996; 109: 2393-2399.