Basic fibroblast growth factor: A treatment for stroke?

Neuroscientist

Volumn 3, Issue 4, 1997, Pages 247-250

  Lin, David A ^a   Finklestein, Seth P ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Basic fibroblast growth factor; Cerebral ischemia; Stroke

Indexed keywords

EID: 0000421762     PISSN: 10738584     EISSN: None     Source Type: Journal    
DOI: 10.1177/107385849700300412     Document Type: Review

References (31)

1. Barnett HJM, Mohr JP, Stein BM, Yatsu FM, editors. Stroke: pathophysiology, diagnosis, and management. 2nd ed. New York: Churchill Livingstone 1992.
2. Finklestein SP, Young AB. Excitotoxic neuronal disease: future therapies for epilepsy, stroke, and degenerative diseases. In: Rosenberg RN, editor. Continuum: lifelong learning in neurology. Minneapolis: American Academy of Neurology 1997:92-112.
3. Loughlin SE, Fallon JH, editors. Neurotrophic factors. San Diego: Academic Press 1993.
4. Chen K, Finklestein SP. Neurotrophic factors. In: Hsu CY, editor. Ischemic stroke, from basic mechanisms to new drug development. Basel: Karger [in press].
5. Ay I, Finklestein SP. Preclinical trials of basic fibroblast growth factor (bFGF) in animal models of stroke. In: Mattson MP, editor. Neuroprotective signal transduction. Totowa (NJ): Humana Press [in press].
6. Kawamata T, Alexis NE, Dietrich WD, Finklestein SP. Intracistemal basic fibroblast growth factor (bFGF) enhances behavioral recovery following focal cerebral infarction in the rat. J Cereb Blood Flow Metab 1996;16:542-547.
7. Kawamata T, Schallert TJ, Dietrich WD, et al. Intracisternal basic fibroblast growth factor (bFGF) enhances functional recovery and upregulates the expression of a molecular marker of neuronal sprouting following focal cerebral infarction [abstract]. Stroke 1997;28:250.
8. Kawamata T, Charette M, Chan T, Finklestein SP. Intracisternal osteogenic protein-1 (OP-1) enhances functional recovery following focal cerebral infarction in the rat [abstract]. Soc Neurosci Abstr 1996;22:1668.
9. Baird A. Fibroblast growth factors: activities and significance of non-neurotrophin neurotrophic growth factors. Curr Opin Neurobiol 1994;4:78-86.
10. Caday CG, Klagsbrun M, Fanning PJ, Mirzabegian A, Finklestein SP. Fibroblast growth factor (FGF) levels in the developing rat brain. Dev Brain Res 1990;52:241-246.
11. Speliotes EK, Caday CG, Do T, Weise J, Kowall NW, Finklestein SP. Increased expression of basic fibroblast growth factor (bFGF) following focal cerebral infarction in the rat. Mol Brain Res 1996;39:31-42.
12. Mattson MP, Barger SW. Programmed cell life: neuroprotective signal transduction and ischemic brain injury. In: Moskowitz MA, Caplan LR, editors. Cerebrovascular diseases: the 19th Princeton stroke conference. Newton (MA): Butterworth Heinemann 1995; 271-290.
13. 2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons. J Neurochem 1995;65:1740-1751.
14. Walicke PA. Basic and acidic fibroblast growth factors have trophic effects on neurons from multiple CNS regions. J Neurosci 1988;8:2618-2627.
15. Pettman B, Weibel M, Sensenbrenner M, Labourdette G. Purification of two astroglial growth factors from bovine brain. FEBS Lett 1985;189:102-108.
16. Puumala M, Anderson RE, Meyer FB. Intraventricular infusion of HBGF-2 promotes cerebral angiogenesis in the Wistar rat. Brain Res 1990;534:283-286.
17. Rosenblatt S, Irikura K, Caday CG, Finklestein SP, Moskowitz MA. Basic fibroblast growth factor (bFGF) dilates rat pial arterioles. J Cereb Blood Flow Metab 1994;14:70-74.
18. Kostyk SK, Kourembanas S, Wheeler EL, et al. Basic fibroblast growth factor increases nitric oxide synthase production in bovine endothelial cells. Am J Physiol 1995;269:H1583-H1589.
19. Koketsu N, Berlove DJ, Moskowitz MA, Kowall NW, Caday CG, Finklestein SP. Pretreatment with intraventricular basic fibroblast growth factor (bFGF) decreases infarct size following focal cerebral ischemia in rats. Ann. Neurol 1994;35:451-457.
20. Fisher M, Meadows M-E, Do T, et al. Delayed treatment with intravenous basic fibroblast growth factor reduces infarct size following permanent focal cerebral ischemia in rats. J Cereb Blood Flow Metab 1995;15:953-959.
21. Jiang N, Finklestein SP, Do T, Caday CG, Charette M, Chopp M. Delayed intravenous administration of basic fibroblast growth factor (bFGF) reduces infarct volume in a model of focal cerebral ischemia/reperfusion in the rat. J Neurol Sci 1996;139:173-179.
22. Tanaka R, Miyasaka Y, Yada K, Ohwada T, Kameya T. Basic fibroblast growth factor increases regional cerebral blood flow and reduces infarct size after experimental ischemia in a rat model. Stroke 1995;26:2154-2159.
23. Bethel A, Kirsch JR, Koehler RC, Finklestein SP, Traystman RJ. Intravenous basic fibroblast growth factor decreases brain injury resulting from focal ischemia in cats. Stroke 1997;28:609-615.
24. Huang Z, Chen K, Huang PL, Finklestein SP, Moskowitz MA. bFGF ameliorates focal ischemic injury by blood flow-independent mechanisms in eNOS mutant mice. Am J Physiol 1997; in press.
25. Nakata N, Kato H, Kogure K. Protective effects of basic fibroblast growth factor against hippocampal neuronal damage following cerebral ischemia in the gerbil. Brain Res 1993;605:354-356.
26. Dietrich WD, Alonso O, Busto R, Finklestein SP. Post-treatment with intravenous basic fibroblast growth factor reduces histopathological damage following fluid-percussion brain injury in rats. J Neurotrauma 1996;6:309-315.
27. Jones TA, Schauert T. Use-dependent growth of pyramidal neurons after neocortical damage. J Neurosci 1994;14:2140-2152.
28. Stroemer RP, Kent TA, Hulsebosch CE. Neocortical neural sprouting, synaptogenesis, and behavioral recovery after neocortical infarction in rats. Stroke 1995;26:2135-2144.
29. Aoyagi A, Nishikawa K, Saito H, Abe K. Characterization of basic fibroblast growth factor-mediated acceleration of axonal branching in cultured rat hippocampal neurons. Brain Res 1994;661:117-126.
30. Benowitz LI, Perrone-Bizzozero NI. The expression of GAP-43 in relation to neuronal growth and plasticity: when, where, how, and why? In: Gispen WH, Routtenberg A, editors. Progress in brain research. Vol. 89. Amsterdam: Elsevier 1991:69-87.
31. Lein P, Johnson M, Guo X, Rueger D, Higgins D. Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons. Neuron 1995;15:597-605.