Synthesis and biology of 3'-N-acyl-N-debenzoylpaclitaxel analogues

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 9, 1999, Pages 2115-2119

  Roh, Eun Joo ^a,b   Song, Choong Eui ^a   Kim, Deukjoon ^b   Pae, Hyun Ock ^c   Chung, Hun Taeg ^c   Lee, Kwan Sun ^d   Chai, Ki Byung ^d   Lee, Chong Ock ^e   Un Choi, Sang ^e  

^a Korea Institute of Science and Technology   (South Korea)

^b Seoul National University   (South Korea)

^c Wonkwang University   (South Korea)

^d Hanmi Pharmaceutical Co Ltd   (South Korea)

^e Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

3' N Acyl N debenzoylpaclitaxel analogues; Apoptosis; Cytotoxicity; Structure activity relationship

Indexed keywords

3' (1 CYCLOHEXENOYL) 3' DEBENZOYLPACLITAXEL; 3' (1 CYCLOPENTENOYL) 3' DEBENZOYLPACLITAXEL; 3' CYCLOHEXANOYL 3' DEBENZOYLPACLITAXEL; 3' CYCLOPENTANOYL 3' DEBENZOYLPACLITAXEL; DNA FRAGMENT; PACLITAXEL; PACLITAXEL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INTRAPERITONEAL DRUG ADMINISTRATION; MELANOMA B16; NONHUMAN;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL DIVISION; HL-60 CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MELANOMA, EXPERIMENTAL; PACLITAXEL; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT;

EID: 0000086317     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00173-X     Document Type: Article

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