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Volumn 7, Issue 11, 2004, Pages 1011-1016

Conus toxins: Targets and properties

Author keywords

Conopeptide; Conus toxins; Drug development; Target

Indexed keywords

ACV 1; AM 336; CALCIUM CHANNEL BLOCKING AGENT; CGX 1160; CONANTOKIN G; CONOPRESSIN DERIVATIVE; CONORFAMIDE; CONOTOXIN; CONTRYPHAN DERIVATIVE; CONTULAKIN; CONTULAKIN G; G PROTEIN COUPLED RECEPTOR; ION CHANNEL; NEUROPROTECTIVE AGENT; NEUROTENSIN RECEPTOR AGONIST; NICOTINIC RECEPTOR BLOCKING AGENT; NORADRENALIN TRANSPORTER; OMEGA CONOTOXIN; OMEGA CONOTOXIN CVID; OMEGA CONOTOXIN MVIIA; OPIATE AGONIST; PROTEIN INHIBITOR; RHO CONOTOXIN; SNAIL VENOM; UNCLASSIFIED DRUG; XEN 2174;

EID: 9944260795     PISSN: 13697056     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (5)

References (33)
  • 1
    • 0030729069 scopus 로고    scopus 로고
    • E.E. Just lecture 1996. Conus venom peptides, receptor and ion channel targets and drug design: 50 million years of neuropharmacology
    • Olivera BM: E.E. Just lecture, 1996. Conus venom peptides, receptor and ion channel targets and drug design: 50 million years of neuropharmacology. Mol Biol Cell (1997) 8 (11 ):2101-2109.
    • (1997) Mol. Biol. Cell , vol.8 , Issue.11 , pp. 2101-2109
    • Olivera, B.M.1
  • 2
    • 0347989461 scopus 로고    scopus 로고
    • Conus venoms: A rich source of novel ion channel-targeted peptides
    • Terlau H, Olivera BM: Conus venoms: A rich source of novel ion channel-targeted peptides. Physiol Rev (2004) 84 (1):41-68.
    • (2004) Physiol. Rev. , vol.84 , Issue.1 , pp. 41-68
    • Terlau, H.1    Olivera, B.M.2
  • 3
    • 1642450641 scopus 로고    scopus 로고
    • Snake and snail toxins acting on nicotinic acetylcholine receptors: Fundamental aspects and medical applications
    • Tsetlin VI, Hucho F: Snake and snail toxins acting on nicotinic acetylcholine receptors: Fundamental aspects and medical applications. FEBS Lett (2004) 557(1-3):9-13.
    • (2004) FEBS Lett. , vol.557 , Issue.1-3 , pp. 9-13
    • Tsetlin, V.I.1    Hucho, F.2
  • 4
    • 0032881372 scopus 로고    scopus 로고
    • Conus peptides targeted to specific nicotinic acetylcholine receptor subtypes
    • Mcintosh JM, Santos AD, Olivera BM: Conus peptides targeted to specific nicotinic acetylcholine receptor subtypes. Annu Rev Biochem (1999) 68:59-88.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 59-88
    • Mcintosh, J.M.1    Santos, A.D.2    Olivera, B.M.3
  • 5
    • 3042631514 scopus 로고    scopus 로고
    • Drugs from the sea: Conopeptides as potential therapeutics
    • Livett BG, Gayler KR, Khalil Z: Drugs from the sea: Conopeptides as potential therapeutics. Curr Med Chem (2004) 11:1715-1723.
    • (2004) Curr. Med. Chem. , vol.11 , pp. 1715-1723
    • Livett, B.G.1    Gayler, K.R.2    Khalil, Z.3
  • 6
    • 0036628335 scopus 로고    scopus 로고
    • Conus peptides and neuroprotection
    • Heading CE: Conus peptides and neuroprotection. Curr Opin Invest Drugs (2002) 3 (6):915-920.
    • (2002) Curr. Opin. Invest. Drugs , vol.3 , Issue.6 , pp. 915-920
    • Heading, C.E.1
  • 7
    • 9944221255 scopus 로고    scopus 로고
    • Elan's Prialt meets endpoint in phase III pain trial
    • Elan Corp plc. Press Release January 07
    • Elan Corp plc: Elan's Prialt meets endpoint in phase III pain trial. Press Release (2004) January 07.
    • (2004)
  • 8
    • 9944253997 scopus 로고    scopus 로고
    • Cognetix Inc, Salt Lake City, UT, USA
    • Cognetix Inc, Salt Lake City, UT, USA. http://www.cognetix.com
  • 10
    • 0035854566 scopus 로고    scopus 로고
    • Autoradiographic localization of N-type VGCCs in gerbil hippocampus and failure of omega conotoxin MVIIA to attenuate neuronal injury after transient cerebral ischemia
    • Azimi-Zonooz A, Kawa CB, Dowell CD, Olivera BM: Autoradiographic localization of N-type VGCCs in gerbil hippocampus and failure of omega conotoxin MVIIA to attenuate neuronal injury after transient cerebral ischemia. Brain Res (2001) 907 1-2):61-70.
    • (2001) Brain Res. , vol.907 , Issue.1-2 , pp. 61-70
    • Azimi-Zonooz, A.1    Kawa, C.B.2    Dowell, C.D.3    Olivera, B.M.4
  • 11
    • 0033952153 scopus 로고    scopus 로고
    • Adverse effects associated with the intrathecal administration of ziconotide
    • Penn RD, Paice JA: Adverse effects associated with the intrathecal administration of ziconotide. Pain (2000) 85 (1-2):291-296.
    • (2000) Pain , vol.85 , Issue.1-2 , pp. 291-296
    • Penn, R.D.1    Paice, J.A.2
  • 13
    • 0003443746 scopus 로고    scopus 로고
    • (Ed): 3rd Edition. Sinauer Associates Inc, Sunderland, MA, USA
    • Hille B (Ed): Ion Channels of Excitable Membranes, 3rd Edition. Sinauer Associates Inc, Sunderland, MA, USA (2001).
    • (2001) Ion Channels of Excitable Membranes
    • Hille, B.1
  • 14
    • 0001847927 scopus 로고    scopus 로고
    • Cloned potassium channels from eukaryotes and prokaryotes
    • Jan LY, Jan YN: Cloned potassium channels from eukaryotes and prokaryotes. Annu Rev Neurosci (1997) 20:91-123.
    • (1997) Annu. Rev. Neurosci. , vol.20 , pp. 91-123
    • Jan, L.Y.1    Jan, Y.N.2
  • 15
    • 0036480194 scopus 로고    scopus 로고
    • Emerging structure of the nicotinic acetylcholine receptors
    • Karlin A: Emerging structure of the nicotinic acetylcholine receptors. Nat Rev Neurosci (2002) 3 2):102-114.
    • (2002) Nat. Rev. Neurosci. , vol.3 , Issue.2 , pp. 102-114
    • Karlin, A.1
  • 16
    • 0000110445 scopus 로고    scopus 로고
    • The structure of neuronal nicotinic receptors
    • Clementi F, Fomassi D, Gotti C (Eds), Springer-Verlag, Berlin, Germany
    • Lindstrom JM: The structure of neuronal nicotinic receptors. In: Handbook of Expenmental Pharmacology, Volume 144. Clementi F, Fomassi D, Gotti C (Eds), Springer-Verlag, Berlin, Germany (2000):101-162.
    • (2000) Handbook of Expenmental Pharmacology , vol.144 , pp. 101-162
    • Lindstrom, J.M.1
  • 17
    • 0036891522 scopus 로고    scopus 로고
    • The diversity of subunit composition in nAChRs: Evolutionary origins, physiologic and pharmacologic consequences
    • Le Novere N, Corringer PJ, Changeux JP: The diversity of subunit composition in nAChRs: Evolutionary origins, physiologic and pharmacologic consequences. J Neurobiol (2002) 53 (4):447-456.
    • (2002) J. Neurobiol. , vol.53 , Issue.4 , pp. 447-456
    • Le Novere, N.1    Corringer, P.J.2    Changeux, J.P.3
  • 19
    • 9944264314 scopus 로고    scopus 로고
    • Structure and functions of cells of the nervous system
    • (Ed): 7th Edition. Allyn and Bacon, Boston, MA, USA
    • Carlson NR (Ed): Structure and functions of cells of the nervous system. In: Physiology of Behaviour, 7th Edition. Allyn and Bacon, Boston, MA, USA (2001):26-62.
    • (2001) Physiology of Behaviour , pp. 26-62
    • Carlson, N.R.1
  • 20
    • 0000351526 scopus 로고    scopus 로고
    • Ziconotide (Elan Pharmaceuticals)
    • Heading CE: Ziconotide (Elan Pharmaceuticals). IDrugs (2001) 4(3):339-350.
    • (2001) IDrugs , vol.4 , Issue.3 , pp. 339-350
    • Heading, C.E.1
  • 21
    • 9944219816 scopus 로고    scopus 로고
    • AMRAD fast tracks development of chronic pain drug
    • AMRAD Corp Ltd: Press Release February 26
    • AMRAD Corp Ltd: AMRAD fast tracks development of chronic pain drug. Press Release (2002) February 26.
    • (2002)
  • 23
    • 0642377359 scopus 로고    scopus 로고
    • Drugs from the sea: Conotoxins as drug leads for neuropathic pain and other neurological conditions
    • Alonso D, Khalib Z, Satkunanthanb N, Livett BG: Drugs from the sea: Conotoxins as drug leads for neuropathic pain and other neurological conditions. Mini Rev Med Chem (2003) 3 7):785-787.
    • (2003) Mini Rev. Med. Chem. , vol.3 , Issue.7 , pp. 785-787
    • Alonso, D.1    Khalib, Z.2    Satkunanthanb, N.3    Livett, B.G.4
  • 24
    • 9944239050 scopus 로고    scopus 로고
    • Metabolic acquires commercial rights to high potential analgesic compound
    • Metabolic Pharmaceuticals Ltd: Press Release September 30
    • Metabolic Pharmaceuticals Ltd: Metabolic acquires commercial rights to high potential analgesic compound. Press Release (2003) September 30.
    • (2003)
  • 26
    • 9944241063 scopus 로고    scopus 로고
    • Investor Update
    • Metabolic Pharmaceuticals Ltd: Press Release September 22
    • Metabolic Pharmaceuticals Ltd: Investor Update. Press Release (2004) September 22.
    • (2004)
  • 27
    • 9944263842 scopus 로고    scopus 로고
    • Studies on neuronal apoptosis in primary forebrain cultures: Neuroprotective/anti-apoptotic action of NR2B NMDA antagonists
    • Abs 747.1
    • Dave JR, Williams AJ, Moffett JR, Koenig ML, Tortella FC: Studies on neuronal apoptosis in primary forebrain cultures: Neuroprotective/anti-apoptotic action of NR2B NMDA antagonists. Abstr Soc Neurosci (2003) 33:Abs 747.1.
    • (2003) Abstr. Soc. Neurosci. , vol.33
    • Dave, J.R.1    Williams, A.J.2    Moffett, J.R.3    Koenig, M.L.4    Tortella, F.C.5
  • 28
    • 9944230231 scopus 로고    scopus 로고
    • Intrathecal administration of CGX-1007, conantokin-G, reduces infarction and cortical spreading depression in a rat model of focal brain ischemia and reperfusion
    • Abs 742.5
    • Tortella FC, Lu XM, Williams AJ, Cunningham B, Stefanik C, Wagstaff J, Hartings JA: Intrathecal administration of CGX-1007, conantokin-G, reduces infarction and cortical spreading depression in a rat model of focal brain ischemia and reperfusion. Abstr Soc Neurosci (2003) 33:Abs 742.5.
    • (2003) Abstr. Soc. Neurosci. , vol.33
    • Tortella, F.C.1    Lu, X.M.2    Williams, A.J.3    Cunningham, B.4    Stefanik, C.5    Wagstaff, J.6    Hartings, J.A.7
  • 30
    • 9944265519 scopus 로고    scopus 로고
    • Drug development: Contulakin-G
    • Cognetix Inc: Company Communication August 14
    • Cognetix Inc: Drug development: contulakin-G. Company Communication (2002) August 14.
    • (2002)
  • 31
    • 9944220287 scopus 로고    scopus 로고
    • Xenome Patent granted in Europe
    • Xenome Ltd: Press Release May 02
    • Xenome Ltd: Xenome Patent granted in Europe. Press Release (2003) May 02.
    • (2003)
  • 32
    • 9944257274 scopus 로고    scopus 로고
    • Xenome begins phase I pain trials with Xen-2174
    • Xenome Ltd: Press Release July 20
    • Xenome Ltd: Xenome begins phase I pain trials with Xen-2174. Press Release (2004) July 20.
    • (2004)
  • 33
    • 9944244307 scopus 로고    scopus 로고
    • Xenome receives $3.2M START grant to develop Chronic Pain Drug with U.S. Expert
    • Xenome Ltd: Press Release November 05
    • Xenome Ltd: Xenome receives $3.2M START grant to develop Chronic Pain Drug with U.S. Expert. Press Release (2003) November 05.
    • (2003)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.