Viral envelope protein glycosylation is a molecular determinant of the neuroinvasiveness of the New York strain of West Nile virus

Journal of General Virology

Volumn 85, Issue 12, 2004, Pages 3637-3645

  Shirato, Kazuya ^a   Miyoshi, Hirotsugu ^a   Goto, Akiko ^a   Ako, Yoshihiko ^a   Ueki, Tomotaka ^a   Kariwa, Hiroaki ^a   Takashima, Ikuo ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ENVELOPE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; STRAIN DIFFERENCE; VIRUS ENCEPHALITIS; VIRUS STRAIN; VIRUS VIRULENCE; WEST NILE FLAVIVIRUS;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; BRAIN; CRICETINAE; FEMALE; GLYCOSYLATION; MALE; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; VIRAL ENVELOPE PROTEINS; VIRULENCE; VIRUS REPLICATION; WEST NILE VIRUS;

WEST NILE VIRUS;

EID: 9944256449     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.80247-0     Document Type: Article

References (30)

1. Anderson, J. F., Vossbrinck, C. R., Andreadis, T. G., Iton, A., Beckwith, W. H., III & Mayo, D. R. (2001). A phylogenetic approach to following West Nile virus in Connecticut. Proc Natl Acad Sci U S A 98, 12885-12889.
2. Beasley, D. W. C., Li, L., Suderman, M. T. & Barrett, A. D. T. (2002). Mouse neuroinvasive phenotype of West Nile virus strains varies depending upon virus genotype. Virology 296, 17-23.
3. Chambers, T. J., Hahn, C. S., Galler, R. & Rice, C. M. (1990). Flavivirus genome organization, expression, and replication. Annu Rev Microbiol 44, 649-688.
4. Chambers, T. J., Halevy, M., Nestorowicz, A., Rice, C. M. & Lustig, S. (1998). West Nile virus envelope proteins: nucleotide sequence analysis of strains differing in mouse neuroinvasiveness. J Gen Virol 79, 2375-2380.
5. Diamond, M. S., Shrestha, B., Marri, A., Mahan, D. & Engle, M. (2003). B cells and antibody play critical roles in the immediate defense of disseminated infection by West Nile encephalitis virus. J Virol 77, 2578-2586.
6. Falgout, B., Pethel, M., Zhang, Y.-M. & Lai, C.A. (1991). Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins. J Virol 65, 2467-2475.
7. Garmendia, A. E., Van Kruiningen, H. J. & French, R. A. (2001). The West Nile virus: its recent emergence in North America. Microbes Infect 3, 223-229.
8. Halevy, M., Akov, Y., Ben-Nathan, D., Kobiler, D., Lachmi, B. & Lustig, S. (1994). Loss of active neuroinvasiveness in attenuated strains of West Nile virus: pathogenicity in immunocompetent and SCID mice. Arch Virol 137, 355-370.
9. Hamman, M. H., Delphine, H. C. & Winston, H. P. (1965). Antigenic variation of West Nile virus in relation to geography. Am J Epidemiol 82, 40-55.
10. Hubálek, Z. & Halouzka, J. (1999). West Nile fever - a reemerging mosquito-borne viral disease in Europe. Emerg Infect Dis 5, 643-650.
11. Johnston, L. J., Halliday, G. M. & King, N. J. C. (2000). Langerhans cells migrate to local lymph nodes following cutaneous infection with an arbovirus. J Invest Dermatol 114, 560-568.
12. Kolykhalov, A. A., Feinstone, S. M. & Rice, C. M. (1996). Identification of a highly conserved sequence element at the 3′ terminus of hepatitis C virus genome RNA. J Virol 70, 3363-3371.
13. Lad, V. J., Shende, V. R., Gupta, A. K., Koshy, A. A. & Roy, A. (2000). Effect of tunicamycin on expression of epitopes on Japanese encephalitis virus glycoprotein E in porcine kidney cells. Acta Virol 44, 359-364.
14. Li, H., Clum, S., You, S., Ebner, K. E. & Padmanabhan, R. (1999). The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids. J Virol 73, 3108-3116.
15. Licon Luna, R. M., Lee, E., Müllbacher, A., Blanden, R. V., Langman, R. & Lobigs, M. (2002). Lack of both Fas ligand and perforin protects from flavivirus-mediated encephalitis in mice. J Virol 76, 3202-3211.
16. Lo, M. K., Tilgner, M., Bernard, K. A. & Shi, P.-Y. (2003). Functional analysis of mosquito-borne flavivirus conserved sequence elements within 3′ untranslated region of West Nile virus by use of a reporting replicon that differentiates between viral translation and RNA replication. J Virol 77, 10004-10014.
17. Matusan, A. H., Pryor, M. J., Davidson, A. D. & Wright, P. J. (2001). Mutagenesis of the Dengue virus type 2 NS3 protein within and outside helicase motifs: effects on enzyme activity and virus replication. J Virol 75, 9633-9643.
18. Scherret, J. H., Mackenzie, J. S., Khromykh, A. A. & Hall, R. A. (2001). Biological significance of glycosylation of the envelope protein of Kunjin virus. Ann N Y Acad Sci 951, 361-363.
19. Seligman, S. J. & Bucher, D. J. (2003). The importance of being outer: consequences of the distinction between the outer and inner surfaces of flavivirus glycoprotein E. Trends Microbiol 11 108-110.
20. Shi, P.-Y., Brinton, M. A., Veal, J. M., Zhong, Y. Y. & Wilson, W. D. (1996). Evidence for the existence of a pseudoknot structure at the 3′ terminus of the flavivirus genomic RNA. Biochemistry 35, 4222-4230.
21. Shirato, K., Mizutani, T., Kariwa, H. & Takashima, I. (2003). Discrimination of West Nile virus and Japanese encephalitis virus strains using RT-PCR RFLP analysis. Microbiol Immunol 47 439-445.
22. Tilgner, M. & Shi, P.-Y. (2004). Structure and function of the 3′ terminal six nucleotides of the West Nile virus genome in viral replication. J Virol 78, 8159-8171.
23. Timofeev, A. V., Butenko, V. M. & Stephenson, J. R. (2004). Genetic vaccination of mice with plasmids encoding the NS1 non-structural protein from tick-borne encephalitis virus and dengue 2 virus. Virus Genes 28, 85-97.
24. Wang, T., Anderson, J. F., Magnarelli, L. A., Bushmich, S., Wong, S., Koski, R. A. & Fikrig, E. (2001a). West Nile virus envelope protein: role in diagnosis and immunity. Ann N Y Acad Sci 951, 325-327.
25. Wang, T., Anderson, J. F., Magnarelli, L. A., Wong, S. J., Koski, R. A. & Fikrig, E. (2001b). Immunization of mice against West Nile virus with recombinant envelope protein. J Immunol 167, 5273-5277.
26. Wang, T., Scully, E., Yin, Z. & 7 other authors (2003a). IFN-γ-producing γδ T cells help control murine West Nile virus infection. J Immunol 171, 2524-2531.
27. + T cells mediate recovery and immunopathology in West Nile virus encephalitis. J Virol 77, 13323-13334.
28. Wu, S.-J. L., Grouard-Vogel, G., Sun, W. & 14 other authors (2000). Human skin Langerhans cells are targets of dengue virus infection. Nat Med 6, 816-820.
29. Xu, G., Xu, X., Li, Z., He, Q., Wu, B., Sun, S. & Chen, H. (2004). Construction of recombinant pseudorabies virus expressing NS1 protein of Japanese encephalitis (SA14-14-2) virus and its safety and immunogenicity. Vaccine 22, 1846-1853.
30. Yun, S.-I., Kim, S.-Y., Rice, C. M. & Lee, Y.-M. (2003). Development and application of a reverse genetics system for Japanese encephalitis virus. J Virol 77, 6450-6465.