Improved diagnosis of pulmonary tuberculosis by detection of free and immune complex-bound anti-30kDa antibodies

Diagnostic Microbiology and Infectious Disease

Volumn 50, Issue 4, 2004, Pages 253-259

  Raja, Alamelu ^a   Uma Devi, K R ^a   Ramalingam, B ^a   Brennan, Patrick J ^b  

^a NATIONAL INSTITUTE FOR RESEARCH IN TUBERCULOSIS   (India)

^b Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

30kDa antigen; Antibody isotypes; Chromatography; Circulating immune complexes; Enzyme linked immunosorbent assay; Pulmonary tuberculosis

Indexed keywords

IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; MACROGOL;

ANTIBODY DETECTION; ANTIBODY TITER; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL;

ANTIBODIES, BACTERIAL; ANTIGEN-ANTIBODY COMPLEX; ANTIGENS, BACTERIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MYCOBACTERIUM TUBERCULOSIS; SENSITIVITY AND SPECIFICITY; TUBERCULOSIS, PULMONARY;

EID: 9944242161     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2004.08.010     Document Type: Article

References (33)

1. Abou-Zeid C., Smith I., Grange J., Ratliff T., Steele J., Rook G. The secreted antigens of Mycobacterium tuberculosis and their relationship with those recognized by the available antibodies. J Gen Microbiol. 134:1988;531-538
2. Allen B., Baker F.J. Treatment of specimens. Baker F.J. Mycobacteria - Isolation, Identification, and Sensitivity Testing. 1968;9-16 Butterworths and Co (Publishers) Ltd, London
3. Benjamin R.G., Debanne S.M., Ma Y., Daniel T.M. Evaluation of mycobacterial antigens in an enzyme-linked immunosorbent assay (ELISA) for the serodiagnosis of tuberculosis. J Med Microbiol. 18:1984;309-318
4. Bentley-Hibbert S.I., Quan X., Neewman T., Huygen K., Godfrey H.P. Pathopysiology of Ag 85 in patients with active tuberculosis Ag 85 circulates as complexes with fibronectin and immunoglobulin G. Infect Immun. 67:1999;581-588
5. Bhattacharya A., Ranadive S., Kalem M., Bhattacharya S. Antibody-based enzyme linked immunosorbent assay for determination of immune complexes in clinical tuberculosis. Am Rev Respir Dis. 134:1986;205-209
6. Bothamley G.H., Rudd R.M. Clinical evaluation of a serological assay using a monoclonal antibody (TB72) to the 38kDa antigen of Mycobacterium tuberculosis. Eur Respir J. 7:1994;240-246
7. Carr R.I., Chakraborty A.K., Brundo M.J., Davidson P.T., Damle P.B., Hardloe M.A., Gilbride K.J., Minden P. Immune complexes and antibodies to BCG in sera from patients with mycobacterial infections. Clin Exp Immunol. 39:1980;562-569
8. Datta M., Gopi P.G., Appegowda B.N., Bhima Rao K.R., Gopalan B.N. Tuberculosis in North Arcot district of Tamil Nadu - a sample survey. Indian J Tuberculosis. 47:2000;147-154
9. Drowart A., Launois P., De Cock J., Yernault J., Van Vooren J.P. An isoelectric focusing method for the study of the humoral response against the Ag 85 complex of Mycobacterium bovis BCG in the different forms of leprosy. J Immunol Methods. 145:1991;223-228
10. Dubaniewicz A. The parameters of the humoral response in the pulmonary tuberculosis. Eur Respir J Suppl. 9:1996;243s
11. Enarson D., Murray J. Global epidemiology of tuberculosis. Rom W.N., Garay S. Tuberculosis. 1996;57-75 Little, Brown and Co, Boston
12. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685
13. Lim J.H., Park J.K., Jo E.K., Song C.H., Dullei M., Song Y.J., Kim H.J. Purification and immunoreactivity of three components from the 30/32-kilodalton Ag 85 complex in Mycobacterium tuberculosis. Infect Immun. 67:1999;6187-6190
14. Mehta P., Khuller G. Comparative evaluation of the diagnostic significance of circulating immune complexes and antibodies to phosphatidylinosito-mannosides in pulmonary tuberculosis by enzyme-linked immunosorbent assay. Med Microbiol. 178:1989;229-233
15. Nagai S., Wiker H.G., Harboe M., Kinomoto M. Isolation and partial characterization of major protein antigens in the culture fluid of Mycobacterium tuberculosis. Infect Immun. 59:1991;372-382
16. O'Farrell P. High-resolution two-dimensional electrophoresis of proteins. J Biol Chem. 250:1975;4007-4021
17. Radhakrishnan V.V., Mathai A., Sundaram P. Diagnostic significance of circulating immune complexes in patients with pulmonary tuberculosis. J Med Microbiol. 36:1992;128-131
18. Raja A., Narayanan P.R., Jawahar M.S., Prabhakar R. Evaluation of Mycobacterium tuberculosis antigen 6 by enzyme linked immunosorbent Assay (ELISA). Indian J Tuberculosis. 41:1994;245-251
19. Raja A., Narayanan P., Mathew R., Prabhakar R. Characterization of mycobacterial antigens and antibodies in circulating immune complexes from pulmonary tuberculosis. J Lab Clin Medicine. 125:1995;581-587
20. Raja A., Uma Devi K.R., Ramalingam B., Brennan P.J. Immunoglobulin G, A and M response in serum and circulating immune complexes against 16kDa antigen of M. tuberculosis. Clin Diagn Lab Immunol. 9:2002;308-312
21. Sada D., Ferguson L.E., Daniel T.M. An ELISA for the serodiagnosis of tuberculosis using a 30,000-Da native antigen of Mycobacterium tuberculosis. J Infect Dis. 162:1990;928-931
22. Salata R.A., Sanson A.J., Malhotra I.J., Wiker H.G., Harboe M., Phillips N.B., Daniel T.M. Purification and characterization of the 30,000 dalton native antigen of Mycobacterium tuberculosis and characterization of six monoclonal antibodies reactive with a major epitope of this antigen. J Lab Clin Med. 118:1991;589-598
23. Samuel A., Ashtekar M., Ganatra R. Significance of circulating immune complexes in pulmonary tuberculosis. Clin Exp Immunol. 58:1984;317-324
24. Senthil Kumar K.S., Uma Devi K.R., Raja A. Isolation and evaluation of diagnostic value of two major secreted proteins of Mycobacterium tuberculosis. Indian J Chest Dis Allied Sci. 44:2002;5-12
25. Simmonney N., Molina J.M., Molimard M., Oksenhendler E., Lagrange P.H. Circulating immune complexes in human tuberculosis sera: demonstration of specific antibodies against Mycobacterium tuberculosis glycolipid (DAT, PGLTB1, LOS) antigens in isolated circulating immune complexes. Eur J Clin Invest. 27:1997;128-134
26. Stroebel A.B., Daniel T.M., Lau J.H.K., Leong J.C.Y., Richarson H. Serologic diagnosis of bone and joint tuberculosis by an enzyme-linked immunosorbent assay. J Infect Dis. 146:1982;280-283
27. Thole J.E.R., Schoningh R., Janson A.A.M., Garbe T., Cornelisse Y.E., Clark-Curtiss J.E., Kolk A.H.J., Ottenhoff T.H.M., De Vries R.R.P., Abou-Zeid C. Molecular and immunological analysis of a fibronectin-binding protein antigen secreted by Mycobacterium leprae. Mol Microbiol. 6:1992;153-163
28. Turneer M., Van Vooren J.P., Nyabenda J., Legros F., Lecomte A., Thiriaux J., Serruys E., Yernault J.C. The humoral immune response after BCG vaccination in humans: consequences for the serodiagnosis of tuberculosis. Eur Respir J. 1:1988;589-593
29. Uma Devi K.R., Ramalingam B., Brennan P.J., Narayanan P.R., Raja A. Specific and early detection of IgG, A and M antibodies to M. tuberculosis 38kDa antigen in pulmonary tuberculosis. Tuberculosis. 81:2001;249-253
30. Uma Devi K.R., Ramalingam B., Raja A. Antibody response to Mycobacterium tuberculosis 30 and 16kDa in pulmonary tuberculosis with human immunodeficiency virus coinfection. Diagn Microbiol Infect Dis. 46:2003;205-209
31. Van Vooren J.P., Drowart A., de Cock M., van Onckelen M.H., D'Hoop M.H., Yernault J.C., Valcke C., Huygen K. Humoral immune response of tuberculous patients against the three components of the Mycobacterium bovis BCG 85 complex separated by isoelectric focusing. J Clin Microbiol. 29:1991;2348-2350
32. Wiker H.G., Harboe M. The Ag 85 Complex: a major secretion product of Mycobacterium tuberculosis. Microbiol Reviews. 56:1992;648-661
33. World Health Organization, Geneva. Antituberculosis drug resistance worldwide. Wkly Epidemiol Rec. 73:1998;249-256