Potent in vivo inhibitors of rat renin: Analogues of human and rat angiotensinogen sequences containing different classes of pseudodipeptides at the scissile site

Journal of Peptide Research

Volumn 50, Issue 4, 1997, Pages 239-247

  Sueiras Diaz, Javier ^a,c   Michael Jones, D ^a   Szelke, Michael ^a   Leckie, Brenda J ^b   Beattie, Sheila R ^b   Beattie, C ^b   Morton, James J ^b  

^a Chilworth Research Centre   (United Kingdom)

^b WESTERN INFIRMARY   (United Kingdom)

^c Ferring Pharmaceuticals AS   (Denmark)

Author keywords

Aminoethylene isostere; Antihypertensives; Hydroxyethylene isostere; Rat renin inhibitors; Renal hypertension; Solid phase peptide synthesis

Indexed keywords

ANGIOTENSINOGEN; PSEUDOPEPTIDE; RENIN; RENIN INHIBITOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE SYNTHESIS; NONHUMAN; PEPTIDE SYNTHESIS; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RAT; RENOVASCULAR HYPERTENSION;

EID: 9844268504     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.1997.tb01465.x     Document Type: Article

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