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Volumn 41, Issue 4, 1997, Pages 463-468

High prevalence of cytotoxin positive Helicobacter pylori in patients unrelated to the presence of peptic ulcers in Japan

Author keywords

Gastritis; Helicobacter pylori; Stomach; Ulcer; VacA

Indexed keywords

CYTOTOXIN; IMMUNOGLOBULIN G;

EID: 9844260054     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.41.4.463     Document Type: Article
Times cited : (41)

References (37)
  • 1
    • 0026594897 scopus 로고
    • Relationship of Helicobacter pylori to serum pepsinogens in an asymptomatic Japanese population
    • Asaka M, Kimura T, Kudo M, Takeda H, Mitani S, Miyazaki T, et al. Relationship of Helicobacter pylori to serum pepsinogens in an asymptomatic Japanese population. Gastroenterology 1992; 102: 760-6.
    • (1992) Gastroenterology , vol.102 , pp. 760-766
    • Asaka, M.1    Kimura, T.2    Kudo, M.3    Takeda, H.4    Mitani, S.5    Miyazaki, T.6
  • 3
    • 0024208785 scopus 로고
    • Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori
    • Marshall BJ, Goodwin CS, Warren JR, Murray R, Bloncow ED, Blackbourn SJ, et al. Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori. Lancet 1988; ii: 1437-42.
    • (1988) Lancet , vol.2 , pp. 1437-1442
    • Marshall, B.J.1    Goodwin, C.S.2    Warren, J.R.3    Murray, R.4    Bloncow, E.D.5    Blackbourn, S.J.6
  • 4
    • 0028039801 scopus 로고
    • Duodenal ulcer healing by eradication of Helicobacter pylori without anti-acid treatment: Randomized controlled trial
    • Hosking SW, Ling TKO, Chung SC, Yung MY, Cheng AF, Sung JJ, et al. Duodenal ulcer healing by eradication of Helicobacter pylori without anti-acid treatment: randomized controlled trial. Lancet 1994; 343: 508-10.
    • (1994) Lancet , vol.343 , pp. 508-510
    • Hosking, S.W.1    Ling, T.K.O.2    Chung, S.C.3    Yung, M.Y.4    Cheng, A.F.5    Sung, J.J.6
  • 6
    • 0025308915 scopus 로고
    • Smoking and the risk of peptic ulcer disease among women in the United States
    • Anda RF, Williamson DF, Escobedo LG, Remington PL. Smoking and the risk of peptic ulcer disease among women in the United States. Arch Intern Med 1990; 150: 1437-41.
    • (1990) Arch Intern Med , vol.150 , pp. 1437-1441
    • Anda, R.F.1    Williamson, D.F.2    Escobedo, L.G.3    Remington, P.L.4
  • 9
    • 0024400603 scopus 로고
    • Chronic antral gastritis, Lewis(a+) phenotype, and male sex as factors in predicting coexisting duodenal ulcer
    • Sipponen P, Aarynen M, Kaariainen I, Kettunen P, Helske T, Seppala K. Chronic antral gastritis, Lewis(a+) phenotype, and male sex as factors in predicting coexisting duodenal ulcer. Scand J Gastroenterol 1989; 24: 581-8.
    • (1989) Scand J Gastroenterol , vol.24 , pp. 581-588
    • Sipponen, P.1    Aarynen, M.2    Kaariainen, I.3    Kettunen, P.4    Helske, T.5    Seppala, K.6
  • 10
    • 0023038765 scopus 로고
    • Duodenal ulcer. Incidence, risk factors, and predictive value of plasma pepsinogen
    • Chuong JJ, Fisher RL, Chuong RL, Spiro HM. Duodenal ulcer. Incidence, risk factors, and predictive value of plasma pepsinogen. Dig Dis Sci 1986; 31: 1178-84.
    • (1986) Dig Dis Sci , vol.31 , pp. 1178-1184
    • Chuong, J.J.1    Fisher, R.L.2    Chuong, R.L.3    Spiro, H.M.4
  • 12
    • 0026485519 scopus 로고
    • High prevalence and persistence of cytotoxin-positive Helicobacter pylori strains in a population with high prevalence of atrophic gastritis
    • Fox JG, Correa P, Taylor NS, Thompson N, Fontham E, Janney F, et al. High prevalence and persistence of cytotoxin-positive Helicobacter pylori strains in a population with high prevalence of atrophic gastritis. Am J Gastroenterol 1992; 87: 1554-60.
    • (1992) Am J Gastroenterol , vol.87 , pp. 1554-1560
    • Fox, J.G.1    Correa, P.2    Taylor, N.S.3    Thompson, N.4    Fontham, E.5    Janney, F.6
  • 13
    • 0025101087 scopus 로고
    • Characterization of and human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity
    • Cover TL, Dooley CP, Blaser MJ. Characterization of and human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity. Infect Immun 1990; 58: 603-10.
    • (1990) Infect Immun , vol.58 , pp. 603-610
    • Cover, T.L.1    Dooley, C.P.2    Blaser, M.J.3
  • 14
    • 0026739795 scopus 로고
    • Purification and characterization of the vacuolating toxin from Helicobacter pylori
    • Cover TL, Blaser MJ. Purification and characterization of the vacuolating toxin from Helicobacter pylori. J Biol Chem 1992; 267: 10570-5.
    • (1992) J Biol Chem , vol.267 , pp. 10570-10575
    • Cover, T.L.1    Blaser, M.J.2
  • 15
    • 0029080739 scopus 로고
    • Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease
    • Ghiara P, Marchetti M, Blaser MJ, Tummuru MK, Cover TL, Segal ED, et al. Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease. Infect Immun 1995; 63: 415460.
    • (1995) Infect Immun , vol.63 , pp. 415460
    • Ghiara, P.1    Marchetti, M.2    Blaser, M.J.3    Tummuru, M.K.4    Cover, T.L.5    Segal, E.D.6
  • 17
    • 0025880541 scopus 로고
    • Production of a cytotoxin by Helicobacter pylori
    • Leunk RD. Production of a cytotoxin by Helicobacter pylori. Rev Infect Dis 1991; 13: S686-9.
    • (1991) Rev Infect Dis , vol.13 , pp. 686-689
    • Leunk, R.D.1
  • 18
    • 0028908420 scopus 로고
    • Cytotoxin production by Helicobacter pylori from patients with upper gastrointestinal tract diseases
    • Tee W, Lambert JR, Dwyer B. Cytotoxin production by Helicobacter pylori from patients with upper gastrointestinal tract diseases. J Clin Microbiol 1995; 33: 1203-5.
    • (1995) J Clin Microbiol , vol.33 , pp. 1203-1205
    • Tee, W.1    Lambert, J.R.2    Dwyer, B.3
  • 19
    • 0026758223 scopus 로고
    • Serum neutralizing antibody response to the vacuolating cytotoxin of Helicobacter pylori
    • Cover TL, Cao P, Murthy UK, Sipple MS, Blaser MJ. Serum neutralizing antibody response to the vacuolating cytotoxin of Helicobacter pylori. J Clin Invest 1992; 90: 913-8.
    • (1992) J Clin Invest , vol.90 , pp. 913-918
    • Cover, T.L.1    Cao, P.2    Murthy, U.K.3    Sipple, M.S.4    Blaser, M.J.5
  • 20
    • 0028107542 scopus 로고
    • High prevalence of neutralizing activity to Helicobacter pylori cytotoxin in serum of gastric-carcinoma patients
    • Hirai M, Azuma T, Ito S, Kato T, Kohli Y, Fujiki N. High prevalence of neutralizing activity to Helicobacter pylori cytotoxin in serum of gastric-carcinoma patients. Int J Cancer 1994; 56: 56-60.
    • (1994) Int J Cancer , vol.56 , pp. 56-60
    • Hirai, M.1    Azuma, T.2    Ito, S.3    Kato, T.4    Kohli, Y.5    Fujiki, N.6
  • 21
    • 0029059733 scopus 로고
    • Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration
    • Atherton JC, Cao P, Peek RJ, Tummuru MK, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem 1995; 270: 17771-7.
    • (1995) J Biol Chem , vol.270 , pp. 17771-17777
    • Atherton, J.C.1    Cao, P.2    Peek, R.J.3    Tummuru, M.K.4    Blaser, M.J.5    Cover, T.L.6
  • 22
    • 0028308711 scopus 로고
    • Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains
    • Cover TL, Tummuru MK, Cao P, Thompson SA, Blaser MJ. Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains. J Biol Chem 1991; 269: 10566-73
    • (1991) J Biol Chem , vol.269 , pp. 10566-10573
    • Cover, T.L.1    Tummuru, M.K.2    Cao, P.3    Thompson, S.A.4    Blaser, M.J.5
  • 24
    • 0001331728 scopus 로고
    • Synthetic peptide vaccine design: Synthesis and properties of a high-density multiple antigenic peptide system
    • Tam JP. Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system. Proc Natl Acad Sci USA 1988; 85: 5409-13
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 5409-5413
    • Tam, J.P.1
  • 25
    • 0030025943 scopus 로고    scopus 로고
    • Nested-polymerase chain reaction for the detection of Helicobacter pylori infection with novel primers designed by sequence analysis of urease A gene in clinically isolated bacterial strains
    • Kawamata O, Yoshida H, Hirota K, Yoshida A, Kawaguchi R, Shiratori Y, et al. Nested-polymerase chain reaction for the detection of Helicobacter pylori infection with novel primers designed by sequence analysis of urease A gene in clinically isolated bacterial strains. Biochem Biophys Res Commun 1996; 219: 266-72.
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 266-272
    • Kawamata, O.1    Yoshida, H.2    Hirota, K.3    Yoshida, A.4    Kawaguchi, R.5    Shiratori, Y.6
  • 26
    • 0028280638 scopus 로고
    • Pathological significance and molecular characterization of the vacuolating toxin gene of Helicobacter pylori
    • Phadnis SH, Ilver D, Janzon L, Normark S, Westblom TU. Pathological significance and molecular characterization of the vacuolating toxin gene of Helicobacter pylori. Infect Immun 1994; 62: 1557-65.
    • (1994) Infect Immun , vol.62 , pp. 1557-1565
    • Phadnis, S.H.1    Ilver, D.2    Janzon, L.3    Normark, S.4    Westblom, T.U.5
  • 27
    • 0028365481 scopus 로고
    • Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: Structural similarities with the IgA protease type of exported protein
    • Schmitt W, Haas R. Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein. Mol Microbiol 1994; 12: 307-19.
    • (1994) Mol Microbiol , vol.12 , pp. 307-319
    • Schmitt, W.1    Haas, R.2
  • 28
    • 0028355422 scopus 로고
    • Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease
    • Telford JL, Ghiara P, Dell'Oreo M, Comanducci M, Burroni D, Bungnoli M, et al. Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease. J Exp Med 1994; 179: 1653-8.
    • (1994) J Exp Med , vol.179 , pp. 1653-1658
    • Telford, J.L.1    Ghiara, P.2    DelL'Oreo, M.3    Comanducci, M.4    Burroni, D.5    Bungnoli, M.6
  • 29
    • 0024498138 scopus 로고
    • Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcers and from patients with chronic gastritis only
    • Figura N, Guglielmetti P, Rossolini A, Barberi A, Cusi G, Musmanno RA, et al. Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcers and from patients with chronic gastritis only. J Clin Microbiol 1989; 27: 225-6.
    • (1989) J Clin Microbiol , vol.27 , pp. 225-226
    • Figura, N.1    Guglielmetti, P.2    Rossolini, A.3    Barberi, A.4    Cusi, G.5    Musmanno, R.A.6
  • 31
    • 0023659137 scopus 로고
    • New metal chelate adsorbent selective for proteins and peptides containing neighbouring histidine residues
    • Hochuli E, Dobeli H, Schacher A. New metal chelate adsorbent selective for proteins and peptides containing neighbouring histidine residues. J Chromatogr 1987; 411: 177-84.
    • (1987) J Chromatogr , vol.411 , pp. 177-184
    • Hochuli, E.1    Dobeli, H.2    Schacher, A.3
  • 32
    • 0028879245 scopus 로고
    • Helicobacter pylori cytotoxin: Importance of native conformation for induction of neutralizing antibodies
    • Manetti R, Massari P, Burroni D, de Bernard D, Marchini A, Olivieri R, et al. Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies. Infect Immun 1995; 63: 4476-80.
    • (1995) Infect Immun , vol.63 , pp. 4476-4480
    • Manetti, R.1    Massari, P.2    Burroni, D.3    De Bernard, D.4    Marchini, A.5    Olivieri, R.6
  • 33
    • 0028860071 scopus 로고
    • Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin
    • Xiang Z, Censini S, Bayeli PF, Telford JL, Figura N, Rappuoli R, et al. Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin. Infect Immun 1995; 63: 94-8.
    • (1995) Infect Immun , vol.63 , pp. 94-98
    • Xiang, Z.1    Censini, S.2    Bayeli, P.F.3    Telford, J.L.4    Figura, N.5    Rappuoli, R.6
  • 34
    • 3543013976 scopus 로고    scopus 로고
    • Diversity of Helicobacter pylori vacA gene in Japanese strains high cytotoxin activity type S1 is dominant in Japan
    • Maeda S, Ogura K, Ishitobi M, Kanai F, Yoshida H, Ota S, et al. Diversity of Helicobacter pylori vacA gene in Japanese strains high cytotoxin activity type S1 is dominant in Japan [abstract]. Gastroenterology 1996; 110: A182.
    • (1996) Gastroenterology , vol.110
    • Maeda, S.1    Ogura, K.2    Ishitobi, M.3    Kanai, F.4    Yoshida, H.5    Ota, S.6
  • 35
    • 0013646891 scopus 로고
    • Table on mortality
    • Health and Welfare Statistics Office. Table on mortality. Journal of Health and Welfare Statistics 1995; 42: 404.
    • (1995) Journal of Health and Welfare Statistics , vol.42 , pp. 404


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