Synthesis, cytotoxicity, antitumor activity and sequence selective binding of two pyrazole analogs structurally related to the antitumor agents U-71, 184 and adozelesin

Anti-Cancer Drug Design

Volumn 12, Issue 7, 1997, Pages 555-576

  Baraldi, Pier Giovanni ^a   Cacciari, Barbara ^a   Romagnoli, Romeo ^a   Spalluto, Giampiero ^a   Gambari, Roberto ^b   Bianchi, Nicoletta ^b   Passadore, Marco ^b   Ambrosino, Piera ^b   Mongelli, Nicola ^c   Cozzi, Paolo ^c   Geroni, Cristina ^c  

^a Dipto di Scienze Farmaceutiche   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c PFIZER INC   (United States)

Author keywords

Adozelesin; Antitumor agents; CC 1065; Cytotoxicity; Polymerase chain reaction; Synthesis

Indexed keywords

ADOZELESIN; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIBIOTIC; DNA; PYRAZOLE DERIVATIVE; RACHELMYCIN; U 71184;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; DRUG CYTOTOXICITY; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; LEUKEMIA L 1210; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; BINDING SITES; CYCLOHEXANECARBOXYLIC ACIDS; CYCLOHEXENES; INDOLES; LEUKEMIA L1210; MAGNETIC RESONANCE SPECTROSCOPY; MICE; NEOPLASM TRANSPLANTATION; POLYMERASE CHAIN REACTION; PYRAZOLES; SPECTROPHOTOMETRY, INFRARED;

ANIMALIA;

EID: 9844257035     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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