Antibody responses to Rhoptry-Associated Protein-1 (RAP-1) of Plasmodium falciparum parasites in humans from areas of different malaria endemicity

Parasite Immunology

Volumn 19, Issue 9, 1997, Pages 387-393

  Jakobsen, P H ^a,b   Kurtzhals, J A L ^a,b   Riley, E M ^c,g   Hviid, L ^a,b   Theander, T G ^a,b   Morris Jones, S ^c   Jensen, J B ^d   Bayoumi, R A L ^e   Ridley, R G ^f   Greenwood, B M ^c,h  

^a Mental Health Services CPH   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

^d BRIGHAM YOUNG UNIVERSITY   (United States)

^e UNIVERSITY OF KHARTOUM   (Sudan)

^f F HOFFMANN LA ROCHE LTD   (Switzerland)

^g UNIVERSITY OF EDINBURGH   (United Kingdom)

^h LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Antibodies; Malaria; Rhoptry associated protein 1

Indexed keywords

PARASITE ANTIGEN;

ADOLESCENT; ADULT; ANTIBODY RESPONSE; ARTICLE; CHILD; CONTROLLED STUDY; ENDEMIC DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GAMBIA; HUMAN; INDONESIA; KENYA; MAJOR CLINICAL STUDY; MALARIA; MALE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; SEASONAL VARIATION; SPLEEN SIZE; SPLENOMEGALY; SUDAN;

PLASMODIUM FALCIPARUM;

EID: 9844255569     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.1997.d01-234.x     Document Type: Article

References (19)

1. Bayoumi R.A., Bashir A.H. & Abdulhadi N.H. (1986) Resistance to falciparum malaria among adults in central Sudan. American Journal of Tropical Medicine and Hygiene 35, 45-55
2. Erunkulu O.A., Hill A.V.S., Kwiatkowski D. et al. (1992) Severe malaria in Gambian children is not due to lack of previous exposure to malaria. Clinical and Experimental Immunology 89, 296-300
3. Gupta S. & Day K. (1994) A theoretical framework for the immunoepidemiology of Plasmodium falciparum malaria. Parasite Immunology 16, 361-370
4. Harnyuttakorn P., McBride J.S., Donachie S., Heidrich H-G. & Ridley R.G. (1992) Inhibitory monoclonal antibodies recognise epitopes adjacent to a proteolytic cleavage site on the RAP-1 protein of Plasmodium falciparum. Molecular and Biochemical Parasitology 55, 177-186
5. Howard R.F. (1992) The sequence of the p82 rhoptry protein is highly conserved between two Plamodium falciparum isolates. Molecular and Biochemical Parasitology 51, 327-330
6. Howard R.F., Jensen J.B. & Franklin H.L. (1993) Reactivity profile of human anti-82-kilodalton rhoptry protein antibodies generated during natural infection with Plasmodium falciparum. Infection and Immunity 61, 2960-2965
7. Howard R.F. & Peterson C. (1996) Limited RAP-1 sequence diversity in field isolates of Plasmodium falciparum. Molecular and Biochemical Parasitology 77, 95-98
8. Jakobsen P.H., Hviid L., Theander T.G. et al. (1993) Specific T-cell recognition of the merozoite proteins Rhoptry-Associated Protein 1 and Erythrocyte-Binding Antigen 1 of Plasmodium falciparum. Infection and Immunity 61, 268-273
9. Jakobsen P.H., Morris-Jones S., Theander T.G. et al. (1994) Increased plasma levels of soluble IL-2R are associated with severe Plasmodium falciparum malaria. Clinical and Experimental Immunology 96, 98-103
10. Jakobsen P.H., Lemnge M.M., Abu-Zeid Y.A. et al. (1996) IgG reactivities to Rhoptry-Associated Protein 1 are associated with decreased levels of Plasmodium falciparum parasitaemia in Tanzanian children. American Journal of Tropical Medicine and Hygiene 55, 642-646
11. Jakobsen P.H., Riley E.M., Allen S.J. et al. (1991) Differential antibody responses of Gambian donors to soluble Plasmodium falciparum antigens. Transaction of the Royal Society of Tropical Medicine and Hygiene 85, 26-32
12. Jensen J.B., Boland M.T., Allan J.S. et al. (1983) Association between human serum-induced crisis forms in cultures of Plasmodium falciparum and clinical immunity to malaria in Sudan. Infection and Immunity 41, 1302-1311
13. Jensen J.B., Hoffman S.L., Boland M.T. et al. (1984) Comparison of immunity to malaria in Sudan and Indonesia: crisis-form versus merozoite-invasion inhibition. Proceedings of the National Academy of Sciences, USA 81, 922-925
14. Ridley R.G., Takacs K., Lahm H. W. et al. (1990a) Characterization and sequence of a protective rhoptry antigen from Plasmodium falciparum. Molecular and Biochemical Parasitology 41, 125-134
15. Ridley R.G., Takacs B., Etlinger H. & Scaife J.G. (1990b) A rhoptry antigen of Plasmodium falciparum is protective in Saimiri monkeys. Parasitology 101, 187-192
16. Riley E.M., Jakobsen P.H., Allen S.J. et al. (1991) Immune responses to soluble exoantigens of Plasmodium falciparum may contribute to both pathogenesis and protection in clinical malaria: evidence from a longitudinal, prospective study of semi-immune African children. European Journal of Immunology 21, 1019-1025
17. Stuber D., Matile H. & Garotti G. (1990) System for high-level production in Escherichia coli and rapid purification of recombinant proteins: application to epitope mapping, preparation of antibodies and structure function analysis. In: Immunological Methods (eds. I. Lefkovits & B. Pernis), pp. 122-152, vol IV, Academic Press, Orlando, USA
18. Theander T.G., Hviid L., Abu-Zeid Y.A. et al. (1990) Reduced cellular immune reactivity in healthy individuals during the malaria transmission. Immunology Letters 25, 237-242
19. Warrell D.A., Molyneux M.E. & Beales P. (1990) Severe and complicated malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene 84 (suppl 1), 1-65