Tumor necrosis factor gene and microsatellite polymorphism in chronic inflammatory bowel diseases;Etude du polymorphisme des microsatellites et des genes du tumor necrosis factor (TNF) au cours des maladies inflammatoires chroniques de l'intestin

Gastroenterologie Clinique et Biologique

Volumn 21, Issue 8-9, 1997, Pages 555-561

  Heresbach, Denis ^a  

^a Service d'Hépato Gastro Entérologie   (France)

Author keywords

Crohn's disease; Inflammatory bowel disease; Microsatellites; Tumor necrosis factor

Indexed keywords

LYMPHOTOXIN; MICROSATELLITE DNA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ALLELE; ARTICLE; CHRONIC DISEASE; CROHN DISEASE; DNA POLYMORPHISM; ENTERITIS; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; ULCERATIVE COLITIS;

ADULT; ALLELES; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 6; CHRONIC DISEASE; COLITIS, ULCERATIVE; CROHN DISEASE; DISEASE SUSCEPTIBILITY; FEMALE; HAPLOTYPES; HUMANS; INFLAMMATORY BOWEL DISEASES; MALE; MICROSATELLITE REPEATS; POLYMORPHISM, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 9844253885     PISSN: 03998320     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (62)

1. Yang H, Rotter JI. Genetics of inflammatory bowel disease. In : Targan SR, Shanahan F, eds. Inflammatory bowel disease : from bench to bedside. Baltimore : Williams and Wilkins, 1994:32-64.
2. Tysk C, Lindberg E, Jämerot G, Floderus-Myrhed B. Ulcerative colitis and Crohn's disease in an unselccted population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking. Gut 1988;29:990-6.
3. Colombel JF, Hugot JP. Génétique de la maladie de Crohn: un modèle complexe. Gastrocnterol Clin Biol 1996;20:B15-B20.
4. Duerr RH. Genetics of inflammatory bowel disease. Inflamm Bowel Dis 1996;2:48-60.
5. Toyoda H, Wang SJ, Yang HY, Redford A, Magalong D, Tyan D et al. Distinct associations of HLA class II genes with inflammatory bowel disease. Gastroenterology 1993;104:741-8.
6. Reinshagen M, Loeliger C, Kuehnl P, Weiss U, Manfras BJ, Adler G et al. HLA class II gene frequencies in Crohn's Disease: a population based analysis in Germany. Gut 1996;38:538-42.
7. Danzé PM, Colombel JF, Jacquot S, Loste MN, Heresbach D, Ategbo S et al. Association of HLA class II genes with susceptibility to Crohn's disease. Gut 1996;39:69-72.
8. Heresbach D, Alizadeh M, Bretagne JF, Gautier A, Quillivic F, Lemarchand B et al. Investigation of the association of major histocompatibility complex genes, including HLA class I, class II and TAP genes, with clinical forms of Crohn's disease. Eur J Immunogen 1996;23:141-51.
9. Hugot JP, Laurent-Puig P, Gower-Rousseau C, Caillat-Zucman S, Bcaugerie L, Dupas JL et al. Linkage analyses of chromosome 6 loci, including HLA, in familial aggregations of Crohn disease. Am J Med Genet 1994;52:207-13.
10. Naom I, Lee J, Ford D, Bowman SJ, Lanchbury JS, Haris I et al. Analysis of the contribution of HLA genes to genetic predisposition in inflammatory bowel disease. Am J Hum Genet 1996,59:226-33.
11. Hugot JP, Laurent-Puig P, Gower-Rousseau C, Olson JM, Lee JC, Beaugcric L et al. Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 1996;379:821-3.
12. Satsangi J, Parkes M, Louis E, Lathrop M, Bell J, Jewell DP. Systematic genome wide search for susceptibility genes in inflammatory bowel disease: evidence for the involvement of non-HLA genes (abstract). Gastroenterology 1996; 110:A1009.
13. Plevy SE,Yang H, Taylor K, Huang Z, Kupelian A, Toyoda H et al. Multiplex family analysis demonstrates linkage of Crohn's disease to the tumor necrosis factor (TNF) locus (abstract). Gastroenterology 1996;110:A993.
14. Sartor RB. Cytokines in intestinal inflammation: pathophysiological and clinical considerations. Gastroenterology 1994; 106:533-9.
15. Olson AD, Ayass M, Chensue S. Tumor necrosis factor and IL-1 β expression in pediatric patients with inflammatory bowel disease. J Pediatr Gastrocnterol Nutr 1993:16:241-6.
16. Murch SH, Braegger CP, Walker-Smith A, MacDonald TT. Location of tumour necrosis factor a by immunohistochemistry in chronic inflammatory bowel disease. Gut 1993;34:1705-9.
17. Isaacs KL, Sartor RB, Haskill S. Cytokinc messenger RNA profiles in inflammatory bowel disease mucosa detected by polymerase chain reaction amplification. Gastroenterology 1992;103:1587-95.
18. Stevens C, Walz G, Singaram C, Lipman ML, Zanker B, Muggia A et al. Tumor necrosis factor α, interleukin-1β and interleukin6 expression in inflammatory bowel disease. Dig Dis Sci 1992:37:818-26.
19. Bouma G, Oudkerk Pool M, Scharenberg JGM, Kolkman JJ, Von Blomberg BME, Schepcr RJ et al. Differences in the intrinsic capacity of peripheral blood mononuclear cells to produce tumor necrosis factor alpha and beta in patients with inflammatory bowel disease and healthy controls. Scand J Gastroenterol 1995;30:1095-100.
20. Maeda M, Watanabe N, Neda H, Yamauchi N, Okamoto T, Sasaki H et al. Serum tumor necrosis factor activity in inflammatory bowel disease. Immunopharmacol Immunotoxicol 1992;14:451-61.
21. Murch SH, Lamkin VA, Savage MO, Walker SJ, McDonald TT. Serum concentrations of tumour necrosis factor α. in childhood chronic inflammatory bowel disease. Gut 1991;32:913-7.
22. Mazlam MZ, Hodgson HJF. Peripheral blood monocyte cytokine production and acute phase response in inflammatory bowel disease. Gut 1992;33:773-8.
23. McDonald TT, Mulchings P, Choy MY, Murch S, Cooke A. Tumor necrosis factor alpha and intcrfcron-gamma production measured at the single cell level in normal and inflamed human intestine. Clin Exp Immunol 1990;81:301-5.
24. Brecse EJ, Michie CA, Nicholls SW, Murch SH, Williams CB, Domizlo P et al. Tumor necrosis factor alpha producing cells in the intestinal mucosa of children with inflammatory bowel disease Gastroenterology 1994; 106:1455-66.
25. Derkx B, Taminiau J, Radema S, Stronkhorst A, Wortel A, Tytgat G et al. Tumor-necrosis factor antibody trcatemcnt in Crohn's Disease (letter). Lancet 1993:342:173-4.
26. Van Dullemen HM, Van Devcnter SJH, Hommes DW, Bijl HA, Jansen J, Tytgat GNJ et al. Treatment of Crohn's disease with anti-tumor necrosis factor chimcric monoclonal antibody (cA2). Gastroenterology 1995;109:129-35.
27. Targan SR, Rutgccrts P, Hanauer SB, Van Deventcr SJH, Mayer L, Present DH et al. A multicenter trial of anti-tumor necrosis factor (TNF) antibody (cA2) for treatment of patients with active Crohn's Disease (abstract). Gastroenterology 1996;110:A1026.
28. Stack W, Mann S, Roy A, Heath P, Sopwith M, Freeman J et al. The effects of CDP571, an engineered human IgG4 anti-TNFα antibody in Crohn's disease (abstract). Gastroenterology 1996;110:A1018.
29. Sands BE, Podolsky DK, Tremaine WJ, Sandbom WJ, Rutgcerts PJ, Hanauer SB et al. Chimcric monoclonal anti-tumor necrosis factor antibody (cA2) in the treatment of severe steroid-refractory ulccrativc colitis (UC) (abstract). Gastroenterology 1996;110:A1008.
30. Plevy SE, Carramanzana NM, Deem RL, Woody JN, Targan SR. Clinical improvement in Crohn's disease (CD) patients treated with anti-TNF-α correlates with down-regulated mucosal T helper responses (abstract). Gastroenterology 1996;110:A993.
31. Pociot F, Briant L, Jougcnecl CV, Molvig J, Worsaac H, Abbal M et al. Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-ct and TNF-β by human mononuclear cells: a possible link to insulindependent diabetes mellitus. Eur J Immunol 1993;23:224-31.
32. Messer G, Spengler U, Jung MC, Honold G, Blömer K, Pape GR et al. Polymorphic structure of the tumor necrosis factor (TNF) locus: an Ncol polymorphism in the first intron of the human TNF-β gene correlates with a variant amino acid in position 26 and a reduced level of TNF-β production. J Exp Med 1991;173:209-19.
33. Bouma G, Crusius JBA, Kostense PJ, Oudkerk-Pool M, Verduijn W, Giphart MJ et al. Secretion of TNFα and LTα in relation to polymorphisms in the TNF genes and HLA-DR alleles, relevance for inflammatory bowel disease (abstract). Gastroenterology 1996;110:A870.
34. Pociot F, Wilson AG, Nerup J, Duff GW. No independent association between a tumor necrosis factor-α promotor region polymorphism and insulin-dependent diabetes mellitus. Eur J Immunol 1993;23:3043-9.
35. Plevy SE, Yang H, Carramanzana NM, Fernandcz D, Gaiennie J, Rotter JI etal. The tumor necrosis factor (TNF) microsatellite haplotype A2B1C2D4E1 correlates with increased TNF production in Crohn's disease (CD) (abstract). Gastroenterology 1996;110:A895.
36. Wilson AG, di Giovine FS, Blakemorc AIF, Duff GW. Single base polymorphism in the human tumour necrosis factor alpha (TNFα) gene detectable by Ncol restriction of PCR product. Hum Mol Gen 1992;1:353.
37. Wilson AG, de Vries N, Pociot F, di Giovine FS, van der Putte LBA, Duff GW. An allelic polymorphism within the human tumor necrosis factor a promoter region is strongly associated with HLA-A1, B8 and DR3 alleles. J Exp Med 1993;177:557-60.
38. D'Alfonso S, Momigliano-Richiardi P. A polymorphic variation in a putative regulation box of the TNFA promoter region. Immunogenetics 1994;39:150-4.
39. Ferencik S, Lindemann M, Horsthemke B, Gross-Wilde H. A new restriction fragment lenght polymorphism of the human TNF-β gene detected by Asp HI digest. Eur J Immunol 1992:19:425-30.
40. Udalova IA, Nedospasov SA, Webb GC, Chaplin DD, Turetskava RL. Highly informative typing of the human TNF locus using six adjacent polymorphic markers. Gcnomics 1993;16:180-6.
41. Nedospasov SA, Udalova IA, Kuprash DV, Turetskaya RL. DNA sequence polymorphism at the human tumor necrosis factor (TNF) locus. Numerous TNF/lymphotoxin alleles tagged by two closely linked microsatellitcs in the upstream region of the lymphotoxin (TNF-β) gene. J Immunol 1991:147:1053-9.
42. Jongcncel CV, Briant L, Udalova IA, Scvin A, Ncdospasov SA, Cambon-Thompsen A. Extensive genetic polymorphism in the human tumor necrosis factor region and relation to extended HLA haplotypcs. Proc Natl Acad Sci USA 1991;88:9717-21.
43. Plevy SE, Targan SR, Yang H, Fcmandcz D, Rotter JI, Toyoda H. Tumor necrosis factor microsatellites define a Crohn's diseaseassociated haplotype on Chromosome 6. Gastroenterology 1996; 110:1053-60.
44. Lcnnard-Jones JE. Classification of inflammatory bowel disease. Scand J Gastroenterol 1989;24 Suppl 170:2-650.
45. Truclovc SC, Willoughby CP, Lee EG, Kettlewell MOW. Further experience in the treatment of severe attacks of ulcerative colitis. Lancet 1978:2:1087-8.
46. Modigliani R, Mary JY, Simon JF, Cortot A, Soule JC, Gendre JP et al. Clinical, biological and endoscopic picture of attacks of Crohn's: evolution on prednisolone. Gastroenterology 1990;98:811-8.
47. Bouma G, Xia B, Crusius JBA, Bloque G, Koutroubakis I, Von Blomberg BME, Meuwisscn SGM et al. Distribution of four polymorphisms in the tumour necrosis factor (TNF) genes in patients with inflammatory bowel disease (IBD). Clin Exp Immunol 1966;103:391-6.
48. Jacob CO, Fronek Z, Lewis GD, Koo M, Hansen JA, McDevitt HO. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor a: relevance to genetic predisposition to systemic lupus erythcmatosus. Proc Natl Acad Sci USA 1990;87:1233-7.
49. Odes HS, Fraser D, Krawiec J. Ulcerative colitis in the Jewish population of Southern Israel 1961-1985: epidemiological and clinical study. Gut 1987;28:1630-6.
50. Roth MP, Peterscn GM, McElrec C, Feldman E, Rotter H. Geographic origins of Jewish patients with inflammatory bowel disease. Gastroenterology 1989;97:900-4.
51. Zlotogora J, Zimmerman J, Rachmilcwitz D. Crohn's disease in Ashkenazi Jews. Gastroenterology 1990;99:286-7.
52. Zlotogora J, Zimmcrman J, Rachmilewitz D. Prevalence of inflammatory bowel disease in family members of Jewish Crohn's Disease patients in Israel. Dig Dis Sci 1991;36:471-5.
53. Roth MP, Petcrsen GM, McElree C, Vadheim CM, Panish JF, Rotter JI. Familial empiric risk estimates of inflammatory bowel disease in Ashkenazi Jews. Gastroenterology 1989;96:1016-20.
54. Crouau-Roy B, Briant L, Bouissou C, Stavropoulos C, Pociot F, Cambon-Thomsen A et al. Tumor necrosis factor microsatellites in four European populations. Human Immunol 1993:38:213-6.
55. Betuel H, Gebuhrer L, Lambert J. Marqueurs HLA de classe II dans les provinces françaises. In: Ohayon E, Cambom-Thomsen A, eds. Génétique des populations humaines. Paris: INSERM, 1986:265-78.
56. Mattiuz PL, Ihde D, Piazza A, Cepcllini R, Bodmcr WF. New approaches to the population genetics and aggregation analysis of the HLA system. In: Terasaki PI, ed. Histocompatibility testings. Copenhagen: Munksgaard, 1970:193-206.
57. Mansfield JC, Holden H, Tarlow JK, di Giovinc FS, McDowcll TL, Wilson AG etal. Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukinc-1 receptor antagonist. Gastroenterology 1994;106:637-42.
58. Heresbach D, Alizadeh M, Dabadie A, Colombel JF, Bretagne JF, Genetet B et al. Study of the polymorphism of genes coding for the synthesis of interleukin Iβ (IL1) and its receptor antagonist (IL1-ra) during inflammatory bowel disease (IBD) (abstract). Am J Gastroenterol 1997 (in press).
59. Sachs JA, Whichelow CE, Hitman GA, Niven M, Thode H, Meager A. The effect of HLA and insulin-dependent diabetes mellilus on the secretion levels of tumor necrosis factors α and β and gamma Interferon. Scand J Immunol 1990:32:703-8.
60. Bouma G, Oudkerk PM, Crusius JBA, Kolkman JJ, Blomberg BME, Meuwissen SGM et al. Haplotype restricted differences in in vitro production of tumor necrosis factor a and lymphotoxin alpha in patients with inflammatory bowel disease and healthy controls (abstract) Neth J Med 1995;46:29A.
61. Andus T, VogI D, Aschcnbrenner E, Köllinger M, Schölmerich J, Gross V. IL-Ira genotype 2 is associated with reduced IL-Ira in colonie mucosa (abstract). Gastroenterology 1996;110:A855.
62. Grell M, Douni E, Wajant H, Lödhen M, Clauss M, Maxeiner B. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. Cell 1995:83:793-802.