The penetration of meropenen in gram negative bacilli. Differences in the activity with imipenem;Penetracion de meropenem en bacilos gramnegativos. Diferencias de actividad con imipenem

Enfermedades Infecciosas y Microbiologia Clinica

Volumn 15, Issue SUPPL. 1, 1997, Pages 14-19

  García De Lomas, Juan ^a   Navarro, David ^a   Gimeno, Concepción ^a  

^a HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

IMIPENEM; MEROPENEM; PENICILLIN BINDING PROTEIN; PORIN; OUTER MEMBRANE PROTEIN; THIENAMYCIN DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL OUTER MEMBRANE; DRUG PENETRATION; DRUG PROTEIN BINDING; ENTEROBACTER CLOACAE; GRAM NEGATIVE BACTERIUM; NONHUMAN; CELL WALL; ESCHERICHIA COLI; METABOLISM; PSEUDOMONAS AERUGINOSA;

BACTERIAL OUTER MEMBRANE PROTEINS; CELL WALL; ESCHERICHIA COLI; GRAM-NEGATIVE BACTERIA; IMIPENEM; PSEUDOMONAS AERUGINOSA; THIENAMYCINS;

EID: 9844247548     PISSN: 0213005X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Nikaido H. Nonspecific transport through the outer membrane. En: Inouye M, ed. Bacterial outer membrane. Nueva York: John Wiley, 1979; 361-407.
2. Nakae T. Outer membrane of Salmonella: isolation of protein complexes that produces transmembrane channels. J Biol Chem 1976; 251: 2.176-2.178.
3. Nikaido H. Outer membrane permeability and β-lactam resistance. En: Schlessinger D, ed. Microbiology 1984. Washington: American Society for Microbiology, 1984; 381-384.
4. Nikaido H, Vaara M. Molecular basis of the outer membrane permeability. Microbiol Rev 1985; 49: 1-32.
5. Neu HC, Labthavikul P. Comparative in vitro activity of N-formimidoyl thienamycin against gram-positive and gram-negative aerobic and anaerobic species and its β-lactamase activity. Antimicrob Agents Chemother 1982; 21: 180-187.
6. Jones RN, Aldridge KE, Allen SD, Barry AL, Fuchs PC, Gerlach EH et al. Multicenter evaluation of SM-7338, a new carbapenem. Antimicrob Agents Chemother 1989; 33: 562-565.
7. Sanders CC, Sanders WE, Thompson KS, Iaconis JP. Meropenem: activity against gram-negative bacteria and interaction with β-lactamases. J Antimicrob Chemother 1989; 24 (Supl A): 133-142.
8. Trias J, Nikaido H. Outer membrane protein D2 catalyzes facilitated diffusion of carbapenems and penems through the outer membrane of Pseudomonas aeruginosa. Antimicrob Agents Chemother 1990; 34: 52-57.
9. Satake S, Yoshihara E, Nahae T. Diffusion of β-lactam antibiotics through liposome membranes reconstituted from purified porins of the outer membrane of Pseudomonas aeruginosa. Antimicrob Agents Chemother 1990; 34: 685-690.
10. Edwards JR. Meropenem: a microbiological overview. J Antimicrob Chemother 1995; 36 (Supl A): 1-17.
11. Livermore DM, Yang YJ. Comparative activity of meropenem against Pseudomonas aeruginosa strains with well characterized resistance mechanisms. J Antimicrob Chemother 1989; 24 (Supl A): 191-198.
12. Masuda N, Ohya S. Cross resistance to meropenem, cephems and quinolones in Pseudomonas aeruginosa. Antimicrob Agents Chemother 1992; 36: 1.847-1.851.
13. Sumita Y, Fukasawa M. Transient carbapenem resistance induced by salycilate in Pseudomonas aeruginosa associated with suppression of outer membrane protein D2 synthesis. Antimicrob Agents Chemother 1993; 37: 2.743-2.746.
14. Pérez FJ, Gimeno C, Navarro D, García de Lomas J. Meropenem permeation through the outer membrane of Pseudomonas aeruginosa can involve pathways other than OprD porin channel. Chemotherapy 1996; 42: 210-214.
15. Angus BL, Carey AM, Caron DA, Koprinski AMB, Hancock REW. Outer membrane permeability in Pseudomonas aeruginosa: a comparison of a wild type with an antibiotic-supersusceptible mutant. Antimicrob Agents Chemother 1982; 21: 299-309.
16. Yoshimura F, Nikaido H. Permeability of Pseudomonas aeruginosa outer membrane to hydrophilic solutes. J Bacteriol 1982; 152: 636-642.
17. Nikaido H, Nikaido K, Harayama S. Identification and characterization of porins in Pseudomonas aeruginosa. J Biol Chem 1991; 266: 770-779.
18. Li XZ, Ma D, Livermore DM, Nikaido H. Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to β-lactam resistance. Antimicrob Agents Chemother 1994; 38: 1.742-1.752.
19. Yoshihara E, Nakae T. Identification of porins in the outer membrane of Pseudomonas aeruginosa that form small diffusion pores. J Biol Chem 1989; 264: 6.297-6.301.
20. Hancock REW, Nikaido H. Outer membrane of gram-negative bacteria. XIX. Isolation from Pseudomonas aeruginosa PAO1 and use in reconstitution and definition of the permeability barrier. J Bacteriol 1978; 136: 381-390.
21. Trias J, Nikaido H. Protein D2 channel of the Pseudomonas aeruginosa outer membrane has a binding site for basic amino acids and peptides. J Biol Chem 1990; 265: 15.680-15.684.
22. Fukuoka T, Masuda N, Takenouchi T, Sekine N, Iijima M, Masuda JI et al. Increase in susceptibility of Pseudomonas aeruginosa to carbapenem antibiotics in low-amino-acid media. Antimicrob Agents Chemother 1991; 35: 529-532.
23. Büscher KH, Cullman WD, Dick W, Opferkuch W. Imipenem resistance in Pseudomonas aeruginosa resulting from diminished expression of an outer membrane protein. Antimicrob Agents Chemother 1987; 31: 703-708.
24. Lynch MJ, Drusano GL, Mobley HLT. Emergence of resistance to carbapenem in Pseudomonas aeruginosa. Antimicrob Agents Chemother 1987; 31: 1.892-1.896.
25. Margaret BS, Drusano GL, Standiford HC. Emergence of resistance to carbapenem antibiotics in Pseudomonas aeruginosa. J Antimicrob Chemother 1989; 24 (Supl A): 161-167.
26. Quinn JP, Dudek EJ, DiVicenzo CA, Lucks DA, Lerner SA. Emergence of resistance to imipenem during therapy for Pseudomonas aeruginosa infection. J Infect Dis 1986; 154: 289-294.
27. Studemeister AE, Quinn JP. Selective imipenem resistance in Pseudomonas aeruginosa associated with diminished outer membrane permeability. Antimicrob Agents Chemother 1988; 32: 1.267-1.268.
28. Trias J, Dufresne J, Levesque RC, Nikaido H. Decreased outer membrane permeability in imipenem-resistant mutants of Pseudomonas aeruginosa. Antimicrob Agents Chemother 1989; 33: 1.201-1.206.
29. Satake SH, Yoneyama H, Nakae T. Role of OmpD2 and chromosomal β-lactamase in carbapenem resistance in clinical isolates of Pseudomonas aeruginosa. J Antimicrob Chemother 1991; 28: 199-207.
30. Zhou XY, Kitzis MD, Guttmann L. Role of cephalosporinase in carbapenem resistance of clinical isolates of Pseudomonas aeruginosa. Antimicrob Agents Chemother 1993; 37: 1.387-1.389.
31. Livermore DM. Interplay of impermeability and chromosomal β-lactamase activity in imipenem-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother 1992; 36: 2.046-2.048.
32. Gimeno C, Navarro D, Savall F, Millás E, Farga MA, Garau J et al. Relationship between outer membrane protein profiles and resistance to ceftazidime, imipenem and ciprofloxacin in Pseudomonas aeruginosa isolates from bacteriemic patients. Eur J Clin Microbiol Infect Dis 1996; 15: 82-85.
33. Yoneyama H, Nakae T. Cloning of the protein D2 gene of Pseudomonas aeruginosa and its functional expression in the imipenem-resistant host. FEBS Lett 1991; 283: 177-179.
34. Huang H, Hancock RE. Genetic definition of the substrate selectivity of outer membrane porin protein OprD of Pseudomonas aeruginosa. J Bacteriol 1993; 175: 7.793-7.800.
35. Gehring KB, Nikaido H. Existence and purification of porin heterotrimers of Escherichia coli K12 OmpC, OmpF, and PhoE proteins. J Biol Chem 1989; 284: 2.810-2.815.
36. Nikaido H, Rosenberg EY. Porin channels in Escherichia coli: studies with liposomes reconstituted from purified porins. J Bacteriol 1983; 153: 241-252.
37. Nikaido H, Rosenberg EY, Foulds J. Porin channels in Escherichia coli: studies with β-lactams in intact cells. J Bacteriol 1983; 153: 232-240.
38. Harder KJ, Nikaido H, Matsuhashi M. Mutants of Escherichia coli that are resistant to certain β-lactam compounds lack the OmpF porin. Antimicrob Agents Chemother 1981; 20: 549-555.
39. Yoshimura F, Nikaido H. Diffusion of β-lactam antibiotics through the porin channels of Escherichia coli K-12. Antimicrob Agents Chemother 1985; 27: 84-92.
40. Cornaglia G, Guan L, Fontana R, Satta G. Diffusion of meropenem and imipenem through the outer membrane of Escherichia coli K-12 and correlation with the antibacterial activities. Antimicrob Agents Chemother 1992; 36: 1.902-1.908.
41. Massida O, Rossolini GM, Satta G. The Aeromonas hydrophila cphA gene: molecular heterogenicity among class B metallo-β-lactamases. J Bacteriol 1991; 173: 4.311-4.317.
42. Cornaglia G, Russell K, Satta G, Fontana R. Relative importances of outer membrane permeability and group 1 β-lactamase as determinants of meropenem and imipenem activities against Enterobacter cloacae. Antimicrob Agents Chemother 1995; 39: 350-355.
43. Lee EH, Collatz E, Trias J, Gutmann L. Diffusion of β-lactam antibiotics into proteoliposomes reconstituted with outer membranes of isogenic imipenem-susceptible and imipenem-resistant strains of Enterobacter cloacae. J Gen Microbiol 1992; 138: 2.347-2.351.
44. Raimondi A, Traverso A, Nikaido H. Imipenem and meropenem resistant mutants of Enterobacter cloacae and Proteus retgeri lack porin. Antimicrob Agents Chemother 1991; 35: 1.174-1.180.
45. Lee EH, Nicolas MH, Kitzkis MD, Pialou G, Collatz E, Gutmann L. Association of two resistance mechanisms in a clinical isolate of Enterobacter cloacae with a high-level resistance to imipenem. Antimicrob Agents Chemother 1991; 35: 1.093-1.098.
46. Chow JW, Shlaes DM. Imipenem resistance associated with the loss of a 40 kDa outer membrane protein in Enterobacter aerogenes. J Antimicrob Chemother 1991; 28: 499-504.
47. Hopkins JM, Towner KJ. Enhanced resistance to cefotaxime and imipenem associated with outer membrane protein alterations in Enterobacter aerogenes. J Antimicrob Chemother 1990; 25: 49-55.