Synthesis and biological activity of potent, low molecular weight renin inhibitors

Journal of Peptide Research

Volumn 50, Issue 4, 1997, Pages 248-261

  Sueiras Diaz, Javier ^a,c   Michael Jones, D ^a   Szelke, Michael ^a   Deinum, Johanna ^b   Svensson, Lennart ^b   Westerlund, Christer ^b   Sohtell, Morgan ^b  

^a Chilworth Research Centre   (United Kingdom)

^b ASTRAZENECA R AND D   (Sweden)

^c Ferring Pharmaceuticals AS   (Denmark)

Author keywords

Hydroxyethylene isostere; Oral absorption; Proteolytic stability; Renin inhibitors

Indexed keywords

HEXANOIC ACID; RENIN INHIBITOR;

AMINO ACID SEQUENCE; ANGIOTENSIN BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; STRUCTURE ACTIVITY RELATION;

EID: 9844241054     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.1997.tb01466.x     Document Type: Article

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