Effect of phosphomonoesters, phosphodiesters, and phosphocreatine on glutamate uptake by synaptic vesicles

Molecular and Chemical Neuropathology

Volumn 32, Issue 1-3, 1997, Pages 89-99

  Xu, Chomg Jun ^a   Kanfer, Julian N ^b   Klunk, William E ^a   Xiong, Qing ^a   Mcclure, Richard J ^a   Pettegrew, Jay W ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Alzheimer disease; D myo inositol 2 monophosphate; D myo inositol 1 monophosphate; L glutamate; Neurotransmitter; Phosphocreatine; sn glycero 3 phosphate; Synaptic vesicles

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM MAGNESIUM); CREATINE PHOSPHATE; GLUTAMIC ACID; GLYCEROPHOSPHATE; GLYCEROPHOSPHOETHANOLAMINE; GLYCEROPHOSPHORYLCHOLINE; INOSITOL PHOSPHATE; ORGANOPHOSPHATE; PHOSPHOETHANOLAMINE; PHOSPHORYLCHOLINE; PHOSPHOSERINE;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; CATTLE; CONTROLLED STUDY; IN VITRO STUDY; NEUROTRANSMITTER UPTAKE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REGULATORY MECHANISM; SYNAPSE VESICLE;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 9844240741     PISSN: 10447393     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02815169     Document Type: Article

References (41)

1. Bennet J. P. (1978) Methods in binding studies, in Neurotransmitter Receptor Binding (Yamamura H. I., Enna S. I., and Kuhar M. J., eds), Raven, New York, pp. 55-90.
2. Blusztajn J. K., Lopez Gonzalez-Coviella I., Logue M., Growdon J. H., and Wurtman R. J. (1990) Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer's disease but not of Down's syndrome patients. Brain Res. 536, 240-244.
3. 3P NMR profiles of Alzheimer's disease and multiple subcortical infarct dementia. Neurology 39, 1423-1427.
4. Coyle J. T. and Puttfarcken P. (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262, 689-695.
5. 2+-ATPase. Biochem. J. 276, 363-367.
6. Fykse E. M., Iversen E. G., and Fonnum F. (1992) Inhibition of L-glutamate uptake into synaptic vesicles. Neurosci. Left. 135, 125-128.
7. Greenamyre J. T. (1986) The role of glutamate in neurotransmission and in neurologic disease. Arch. Neurol. 43, 1058-1065.
8. Hirose K. and Chan P. H. (1993) Blockade of glutamate excitotoxicity and its clinical applications. Neurochem. Res. 18, 479-483.
9. Hirvonen M. R. (1991) Cerebral lithium, inositol and inositol monophosphate. Pharmacol. Toxicol. 69, 22-27.
10. Kish P. E. and Ueda T. (1989) Glutamate accumulation into synaptic vesicles. Methods Enzymol. 174, 9-25.
11. Klunk, W. E., McClure R. J., and Pettegrew J. W. (1991) L-Phosphoserine, a metabolite elevated in Alzheimer's disease, interacts with specific L-glutamate receptor subtypes. J. Neurochem. 56, 1997-2003.
12. B receptor: A comparision of phosphoethanolamine and 3-amino-propylphosphonic acid. Mol. Chem. Neuropathol. 26, 15-30.
13. 31P MRS extracts of postmortem Alzheimer's disease brain. Neurobiol. Aging 17, 349-357.
14. Koh J. Y., Yang L. L., and Cotman C. W. (1990) Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res. 522, 315-320.
15. Kowall, N. W. and Beal, M. F. (1991) Glutamate-, glutaminase-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease. Ann. Neurol. 29, 162-167.
16. Lobur A. T., Kish P. E., and Ueda, T. (1990) Synaptic vesicular glutamate uptake modulation by a synaptosomal cytosolic factor. J. Neurochem. 54, 1614-1618.
17. Lowry O. H., Rosebrough N. J., Farr A. L., and Randall R. J. (1951) Protein measurement with the Polin phenol reagent. J. Biol. Chem. 193, 265-275.
18. Majerus P. W. (1992) Inositol phosphate biochemistry. Annu. Rev. Biochem. 61, 225-250.
19. Mattson M. P., Cheng B., Davis D., Bryant K., Lieberburg I., and Rydel R. E. (1992) Beta-amyloid peptides destablize calcium homeostasis and render human cortical neurons vulnerable to excitotoxity. J. Neurosci. 12, 376-389.
20. McCulloch J. (1992) Excitatory amino acid antagonist and their potential for the treatment of ischemic brain damage in man. Br. J. Clin. Pharmacol. 34, 106-114.
21. Michaelis T., Merboldt K. D., Bruhn H., Hanicke, W., and Frahm J. (1993) Absolute concentrations of metabolites in the adult human brain in vivo: Quantification of localized proton NMR spectra. Radiology 187, 219-227.
22. 2+-ATPaSe acts as a proton pump. J. Biochem. 95, 995-1007.
23. Myhrer T. (1993) Animal models of Alzheimer's disease: Glutamatergic denervation as an alternative approach to cholinergic devervation. Neurosci. Biobehav. Rev. 17, 195-202.
24. Naito S. and Ueda T. (1985) Characterization of glutamate uptake into synaptic vesicles. J. Neurochem. 44, 99-109.
25. Nalepa I., Pintor A., Fortuna S., Vetulani J., and Michalek H. (1989) Increased responsiveness of the cerebral cortical phosphatidylinositol system to noradrenaline and carbachol in senescent rats. Neurosci. Lett. 107, 195-199.
26. Nicholls D. G. and Sihra T. S. (1986) Synaptosomes possess an exocytotic pool of glutamate. Nature 321, 772-773.
27. Nitsch R., Blusztajn J. K., Pittas A. G., Slack B. E., Growdon J. H., and Wurtman R. J. (1992) Evidence for a membrane defect in Alzheimer's disease brain. Proc. Natl. Acad. Sci. USA 89, 1671-1675.
28. Pettegrew J. W., Panchalingam K., Moossy J., Martinez J., Rao G., and Boiler F. (1988a) Correlation of phosphorus-31 magnetic resonance spectroscopy and morphologic findings in Alzheimer's disease. Arch. Neurol. 45, 1093-1096.
29. 31P Nuclear magnetic resonance study of the brain in Alzheimer's disease. J. Neuropathol. Exp. Neurol 47, 235-248.
30. Pettegrew J. W., Panchalingam K., Klunk W. E., McClure R. J., and Muenz L. R. (1994) Alterations of cerebral metabolism in probable Alzheimer's disease. A preliminary study. Neurobiol. Aging 15, 117-132.
31. Riveros N., Fiedler J., Lagos N., Munoz C., and Orrego F. (1986) Glutamate in rat brain cortex synaptic vesicles: Influence of the vesicle isolation procedure. Brain Res. 386, 405-408.
32. Rosenberg P. A. and Aizenman E. (1989) Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex. Neurosci. Lett. 103, 162-168.
33. Rothman S. M. and Olney J. W. (1987) Excitotoxicity and the NMDA receptor. Trends Neurosci. 10, 299-302.
34. Rothstein J. D., Martin L. J., and Kuncl R. W. (1992) Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N. Engl. J. Med. 326, 1464-1468.
35. Sherman W. R., Munsell L. Y., Gish B. G., and Honchar M. P. (1985) Effects of systematically administered lithium on phosphoinositide metabolism in rat brain, kidney, and testis. J. Neurochem. 44, 798-807.
36. 31P Magnetic resonance spectroscopy in Alzheimer's and Pick's disease. Neurobiol. Aging 14, 85-92.
37. Storm-Mathisen J., Leknes A. K., Bore A. T., Vaaland J. L., Edminson P., Haug F-M. S., and Ottersen O. P. (1983) First visualization of L-glutamate and GABA in neurones by immunocytochemistry. Nature 301, 517-520.
38. Tabb J. S. and Ueda T. (1991) Phylogenetic studies on the synaptic vesicle glutamate transport system. J. Neurosci. 11, 1822-1828.
39. Tabb J. S., Kish P. E., Dyke R. V., and Ueda T. (1992) Glutamate transport into synaptic vesicle. Roles of membrane potential, pH gradient, and intravesicular pH. J. Biol. Chem. 267, 15,412-15,418.
40. Watkins J. C., Krogsgaard-Larsen P., and Honore T. (1990) Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. Trends Pharmacol. Sci. 11, 25-33.
41. Xu J. C., Klunk W. E., Kanfer J. N., Xiong Q., Miller G., and Pettegrew J. W. (1996) Phosphocreatine-dependent glutamate uptake by synaptic vesicles. A comparison with ATP dependent glutamate uptake. J. Biol. Chem. 271, 13,435-13,440.