Prophylactic use of low-dose urodilatin for prevention of renal impairment following liver transplantation: A randomized placebo-controlled study

Clinical Transplantation

Volumn 11, Issue 6, 1997, Pages 593-598

  Langrehr, Jan M ^a   Kahl, Andreas ^a   Meyer, Markus ^b   Neumann, Ulf ^a   Knoop, Michael ^a   Jonas, Sven ^a   Steinmüller, Thomas ^a   Bechstein, Wolf Otto ^a   Frei, Ulrich ^a   Forssmann, Wolf Georg ^b   Neuhaus, Peter ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b IPF PHARMACEUTICALS GMBH   (Germany)

Author keywords

Liver transplantation; Renal function; Urodilatin

Indexed keywords

CREATININE; FUROSEMIDE; LOOP DIURETIC AGENT; NATRIURETIC FACTOR; URODILATIN;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; FEMALE; HUMAN; KIDNEY FAILURE; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ADULT; ATRIAL NATRIURETIC FACTOR; CREATININE; DIURETICS; DRUG ADMINISTRATION SCHEDULE; FEMALE; GRAFT SURVIVAL; HUMANS; IMMUNOSUPPRESSION; KIDNEY FAILURE; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; PEPTIDE FRAGMENTS; RENAL DIALYSIS; STATISTICS, NONPARAMETRIC; SURVIVAL ANALYSIS;

EID: 9844240495     PISSN: 09020063     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. MCCAULEY J, VAN THIEL DH, STARZL TE, PUSCHETT JB. Acute and chronic renal failure in liver transplantation. Nephron 1990: 55: 121.
2. PLATZ KP, MULLER AR, BLUMHARDT G, et al. Nephrotoxicity following orthotopic liver transplantation. A comparison between cyclosporine and FK506. Transplantation 1994: 58: 170.
3. KLINTMALM GBG, IWATSUKI S, STARZL TE. Nephrotoxicity of cyclosporine a in liver and kidney transplant patients. Lancet 1981: I: 470.
4. ANDRÉS A, MORALES JM, FARIAS J, et al. Acute renal failure after liver transplantation in patients treated with cyclosporine. Transpl Proc 1992: 24(1): 126.
5. DANOVICH GM, WILKINSON AH, COLONNA JO, BUSUTTIL RW. Determinants of renal failure in patients receiving orthotopic liver transplants. Kidney Int 1987: 31: 191.
6. WILLIAMS R, BLACKBURN A, NEUBERGER J, CALNE RY. Long-term use of cyclosporine in liver grafting. Q J Med 1987: 57: 897.
7. SHILLIDAY I, ALLISON MEM. Diuretics in acute renal failure. Renal Failure 1994: 16: 3.
8. SCHRAMM L, HEIDBREDER E, SCHAAR J, et al. Toxic acute renal failure in the rat: effects of diltiazem and urodilatin on renal function. Nephron 1994: 68: 454.
9. SCHULZ-KNAPPE P, FORSSMANN K, HERBST F, HOCK D, PIPKAORN R, FORSSMANN WG. Isolation and structural analysis of "urodilatin", a new peptide of the cardiodilatin-(ANP)-family, extracted from human urine. Klin Wochenschr 1988: 66: 752.
10. FLÜGGE G, INAGAMI T, FUCHS E. Atrial natriuretic peptide detected by immunocytochemistry in peripheral organs of Tupaia belangen. Histochemistry 1987: 86: 479.
11. ZEIDEL ML. Hormonal regulation of inner medullary collecting duct sodium transport. Am J Physiol 1993: 265: F159.
12. RIEGGER GAJ, ELSNER D, FORSSMANN WG, KROMER EP. Effects of ANP-(95-126) in dogs before and after induction of heart failure. Am J Physiol 1990: 259: H1643.
13. CEDIDI C, MEYER M, KUSE ER, et al. Urodilatin: a new approach for the treatment of therapy-resistant acute renal failure after liver transplantation. Eur J Clin Invest 1994: 24: 632.
14. HUMMEL M, KUHN M, BUB A, et al. Urodilatin: a new peptide with beneficial effects in the postoperative therapy of cardiac transplant recipients. Clin Invest 1992: 70: 674.
15. NEUHAUS P, BLUMHARDT G, BECHSTEIN WO, STEFFEN R, PLATZ KP, KECK H. Technique and results of biliary reconstruction using side-to-side choledochocholedochostomy in 300 orthotopic liver transplants. Ann Surg 1994:219: 426.
16. NEUHAUS P, BECHSTEEN WO, BLUMHARDT G, et al. Comparison of quadruple immunosuppression after liver transplantation with ATG or IL-2 receptor antibody. Transplantation 1993: 55: 1320.
17. IWATSUKI S, ESQUIVEL CO, KLINTMALM GBG, GORDON RD, SHAW BW, STARZL TE. Nephrotoxicity of cyclosporine m liver transplantation. Transpl Proc 1985: 17(Suppl 1): 191.
18. GUNNING TC, BROWN MR, SWEGERT TH, et al. Perioperative renal function in patients undergoing orthotopic liver transplantation. Transplantation 1991: 51: 422.
19. BENNETT WM, ELZINGA LW, PORTER GA. Tubulointerstitial disease and toxic nephropathy. In: BRENNER BM, RECTOR FC (eds.), The Kidney. Fourth ed. New York: WB Saunders Co., 1991, p. 1430-1497.
20. DECRUYENAERE J, COLARDYN F, MORTIER E, et al. Early postoperative renal dysfunction after adult liver transplantation. Transpl Proc 1995: 27: 3497.
21. RIMOLA A, GALVER JS, SCHADE RR, EL-LANKANY S, STARZL TE, VAN THIEL DH. Effects of renal impairment on liver transplantation. Gastroenterology 1987: 93: 148.
22. CRAWFORD DHG, ENDRE ZH, AXELSEN RA, et al. Universal occurrence of glomerular abnormalities in patients receiving liver transplants. Am J Kidney Dis 1992: 19: 339.
23. NOCHY D, CALLARD P, BELLON B, BARIETY J, DRUET P. Association of overt glomerulonephritis and liver disease. A study of 34 patients. Clin Nephrol 1976: 6: 422.
24. JINDAL RM, POPESCU I. Renal dysfunction associated with liver transplantation. Postgrad Med J 1995: 71: 513.
25. GONWA TA, KLINTMALM GB, LEVY M, JENNINGS LS, GOLDSTEIN RM, HUSBERG BS. Impact of pretransplant renal function on survival after liver transplantation. Transplantation 1995: 59: 361.