Participation of kinins in the inhibitory action of captopril on acute hypertension induced by L-NAME in anesthetized rats

Brazilian Journal of Medical and Biological Research

Volumn 30, Issue 10, 1997, Pages 1219-1223

  Soares De Moura, R ^a   Cardoso Leao M ^a  

^a STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Captopril; HOE 140; L NAME; Rat arterial blood pressure

Indexed keywords

ARGININE METHYL ESTER; BRADYKININ; CAPTOPRIL; ICATIBANT;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; HYPERTENSION; INHIBITION KINETICS; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRESSURE TRANSDUCER; RAT; VASODILATATION;

ANIMALIA; RATTUS NORVEGICUS;

EID: 9844229897     PISSN: 0100879X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0100-879X1997001000013     Document Type: Article

References (20)

1. Rees DD, Palmer RMJ & Moncada S (1989). Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proceedings of the National Academy of Sciences, USA, 86: 3375-3378.
2. Ribeiro MO, Antunes E, de Nucci G, Lovisolo SM & Zatz R (1992). Chronic inhibition of nitric oxide synthesis. A new model of arterial hypertension. Hypertension, 20: 298-303.
3. Scares de Moura R, Leâo MC, Lourenço CD, Monnerat Lemos AJ & Salvaro P (1992). Captopril prevents hypertension developed by inhibition of nitric oxide synthesis induced by chronic treatment of rats with L-NAME. British Journal of Pharmacology, 107: 199P (Abstract).
4. Pollock DM, Polakowski JS, Divish BJ & Opgenorth TJ (1993). Angiotensin blockade reverses hypertension during long-term nitric oxide synthase inhibition. Hypertension. 21: 660-666.
5. Mombouli JV & Vanhoutte PM (1995). Endothelium-derived hyperpolarizing factor(s) and the potentiation of kinins by converting enzyme inhibitors. American Journal of Hypertension, 8: 19S-27S.
6. 140, a new potent and long acting bradykinin-antagonist: in vivo studies. British Journal of Pharmacology, 102: 774-777.
7. Gardiner SM, Comptom AM, Bennet T, Palmer RMJ & Moncada S (1990). Control of regional blood flow by endothelium-derived nitric oxide. Hypertension, 15: 486-492.
8. Navarre J, Sanchez A, Séiz J, Ruilope LM, Garcia-Estan J, Romero JC, Morcada S & Lahera V (1994). Hormonal, renal, and metabolic alterations during hypertension induced by chronic inhibition of NO in rats. American Journal of Physiology, 267: R1516-R1521.
9. Cunha RS, Cabrai AM & Vasquez EC (1993). Evidence that autonomic nervous system plays a major role in the L-NAME-induced hypertension in conscious rats. American Journal of Hypertension, 6: 806-809.
10. Richard V, Hogie M, Clozel M, Löffler B-M & Thuillez C (1995). In vivo evidence of an endothelin-induced vasopressor tone after inhibition of nitric oxide synthesis in rats. Circulation, 91: 771-775.
11. G-monomethyl-L-arginine and nitroarginine potentiate pressor responsiveness of vasoconstrictors in conscious rats. American Journal of Physiology, 262: R1137-R1144.
12. G-nitro-L-arginine as affected by blockade of pressor mechanisms mediated by the sympathetic nervous system, angiotensin, prostanoids and vasopressin. Journal of Pharmacology and Experimental Therapeutics, 261: 240-245.
13. ωnitro-L-arginine methyl ester administration. Journal of Cardiovascular Pharmacology, 23: 765-771.
14. Zanziger J, Zheng X & Bassenge E (1994). Endothelium dependent vasomotor responses to endogenous agonists are potentiated following ACE inhibition by a bradykinin dependent mechanism. Cardiovascular Research, 28: 209-214.
15. Bossaler C, Auch-Schwelk W, Weber F, Götze S, Gräfe M, Graf K & Fleck E (1992). Endothelium-dependent relaxations are augmented in rats chronically treated with the angiotensin-converting enzyme inhibitor enalapril. Journal of Cardiovascular Pharmacology, 20: S91-S95.
16. Manning Jr DR, Hu L & Williamson TD (1994). Mechanisms involved in the cardiovascular-renal actions of nitric oxide inhibition. Hypertension, 23: 951-956.
17. Goldschmidt JE & Tallarida RJ (1991). Pharmacological evidence that captopril possesses an endothelium-mediated component of vasodilation: effect of sulfhydryl groups on endothelium-derived relaxing factor. Journal of Pharmacology and Experimental Therapeutics, 257: 1136-1145.
18. Pontieri V, Lopes OU & Ferreira SH (1990). Hypotensive effect of captopril. Role of bradykinin and prostaglandin like substances. Hypertension, 15 (Suppl I): I.55-I.58.
19. Salgado MCO & Name CF (1994). Role of kinins in the acute antihypertensive effect of enalapril in hypertensive rats. Brazilian Journal of Medical and Biological Research. 27: 1391-1401.
20. Bouaziz H, Joulin Y, Safar M & Benetos A (1994) Effects of bradykinin B2 receptor antagonism on the hypotensive effects of ACE inhibition. British Journal of Pharmacology, 113: 717-722.